Search
Results: 417
Molecular Approaches to the Genetics of Obesity: Mapping and Characterization of the Murine Diabetes (db) Gene
Nathan Bahary
Jan 01, 0001
Studies of twins, adopted children, and some human populations indicate that there is a substantial genetic influence on body composition in both children and adults. However, in no single instance in either man or animals is...
Published by: Rockefeller University
Early Pregnancy-Associated Plasma Protein A Concentrations are Associated with Third Trimester Insulin Sensitivity
Hypertension Pregnancy-Induced Pregnancy Insulin Resistance blood pressure blood arterial Glucose Gestational diabetes Bodily Secretions Fasting Infant Pregnancy Trimester Second Pregnancy Trimester Third Pregnancy-Associated Plasma Protein-A Insulin pressure-physical agent oral glucose tolerance test early stage of pregnancy insulin sensitivity patient disposition
Measurement delay associated with the Guardian RT continuous glucose monitoring system.
AIMS: Using compartment modelling, we assessed the time delay between blood glucose and sensor glucose measured by the Guardian RT continuous glucose monitoring system in young subjects with Type 1 diabetes (T1D). METHODS...
Multi-parametric flow cytometric and genetic investigation of the peripheral B cell compartment in human type 1 diabetes.
WS Thompson, ML Pekalski, HZ Simons, DJ Smyth, X Castro-Dopico, H Guo, C Guy, DB Dunger, S Arif, M Peakman, C Wallace, LS Wicker, JA Todd, RC Ferreira
Feb 21, 2020
The appearance of circulating islet-specific autoantibodies before disease diagnosis is a hallmark of human type 1 diabetes (T1D), and suggests a role for B cells in the pathogenesis of the disease. Alterations in the peripheral...
B lymphocytes il-2 IL-21 PTPN22 human immunology Immunophenotyping type 1 diabetes Adolescent Adult Age Factors Autoantibodies B-Lymphocyte Subsets Case-Control Studies Child Cytokines Diabetes mellitus Type 1 Female Flow Cytometry Gene Expression Regulation Genetic Association Studies Humans Immunophenotyping Male Phenotype Protein Tyrosine Phosphatase Non-Receptor Type 22 Signal Transduction Young Adult
Cells with Treg-specific FOXP3 demethylation but low CD25 are prevalent in autoimmunity
RC Ferreira, HZ Simons, WS Thompson, DB Rainbow, X Yang, AJ Cutler, J Oliveira, X Castro Dopico, DJ Smyth, N Savinykh, M Mashar, TJ Vyse, DB Dunger, H Baxendale, A Chandra, C Wallace, JA Todd, LS Wicker, ML Pekalski
Sep 26, 2017
Association analysis of the IGF1 gene with childhood growth, IGF-1 concentrations and type 1 diabetes.
A Vella, N Bouatia-Naji, B Heude, JD Cooper, CE Lowe, C Petry, SM Ring, DB Dunger, JA Todd, KK Ong
Aug 08, 2017
AIMS/HYPOTHESIS: Insulin-like growth factor-1 is a major childhood growth factor and promotes pancreatic islet cell survival and growth in vitro. We hypothesised that genetic variation in IGF1 might be associated with childhood...
The role of inflammatory pathway genetic variation on maternal metabolic phenotypes during pregnancy
M Urbanek, MG Hayes, H Lee, RM Freathy, LP Lowe, C Ackerman, N Jafari, AR Dyer, NJ Cox, DB Dunger, AT Hattersley, BE Metzger, WL Lowe
Apr 04, 2017
Asian Continental Ancestry Group Blood Glucose C-Peptide Cohort Studies European Continental Ancestry Group Fasting Female Genetic Predisposition to Disease Glucose Tolerance Test Hemoglobin A Glycosylated Humans Hyperglycemia Inflammation Interleukin-6 Interleukin-8 Polymorphism Single Nucleotide Pregnancy Pregnancy Complications Pregnancy Outcome Receptors Adiponectin Receptors Leptin Resistin Signal Transduction Thailand Tumor Necrosis Factor-alpha
Developmental programming
EF Sutton, LA Gilmore, DB Dunger, BT Heijmans, M-F Hivert, C Ling, JA Martinez, SE Ozanne, RA Simmons, M Szyf, RA Waterland, LM Redman, E Ravussin
May 15, 2019
Safety, efficacy and glucose turnover of reduced prandial boluses during closed-loop therapy in adolescents with type 1 diabetes
D Elleri, M Biagioni, JM Allen, K Kumareswaran, L Leelarathna, K Caldwell, M Nodale, ME Wilinska, A Haidar, P Calhoun, C Kollman, NC Jackson, AM Umpleby, CL Acerini, DB Dunger, R Hovorka
Aug 11, 2015
closed-loop insulin delivery postprandial hypoglycaemia type 1 diabetes Adolescent Algorithms Blood Glucose Cross-Over Studies Diabetes mellitus Type 1 Drug Administration Schedule England Female Glycemic Load Humans Hyperinsulinism Hypoglycemia Hypoglycemic Agents Injections Subcutaneous Insulin Insulin Infusion Systems Insulin Resistance Male Meals Monitoring Physiologic risk
Factors Associated With Glycemic Control During Free-Living Overnight Closed-Loop Insulin Delivery in Children and Adults With Type 1 Diabetes.
M Tauschmann, H Thabit, L Leelarathna, D Elleri, JM Allen, A Lubina-Solomon, M Stadler, E Walkinshaw, A Iqbal, P Choudhary, ME Wilinska, SR Heller, SA Amiel, ML Evans, DB Dunger, R Hovorka
Oct 21, 2015
closed-loop insulin delivery glycemic control home study predictive factors type 1 diabetes Adolescent Adult Age Factors Biomarkers Blood Glucose Diabetes mellitus Type 1 Hemoglobin A Glycosylated Humans Hypoglycemia Hypoglycemic Agents Insulin Insulin Infusion Systems Linear Models Randomized Controlled Trials as Topic Risk Factors Time Factors Treatment Outcome
|
|< |
< |
1 |