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Reply to Sharp et al.
Sharp et al. (1) suggest that our original findings refute rather than support the effectiveness of psychological targeting (2, 3). We respectfully disagree for the following reasons.
Transient computations using the natural stress formulation for solving sharp corner flows
In this short communication, we analyse the potential of the natural stress formulation (NSF) (i.e. aligning the stress basis along streamlines) for computing planar flows of an Oldroyd-B fluid around sharp corners. This is...
O-Antigen-Dependent Colicin Insensitivity of Uropathogenic Escherichia coli.
Connor Sharp, Christine Boinett, Amy Cain, Nicholas G Housden, Sandip Kumar, Keith Turner, Julian Parkhill, Colin Kleanthous
Aug 20, 2019
The outer membrane of Gram-negative bacteria presents a significant barrier for molecules entering the cell. Nevertheless, colicins, which are antimicrobial proteins secreted by Escherichia coli, can target other E. coli cells...
bacteriocins cell envelope enteric bacteria outer membrane Anti-Bacterial Agents Colicins DNA Transposable Elements Drug Resistance Bacterial Gene Silencing metabolism Microarray Analysis Microbial Sensitivity Tests Mutagenesis Insertional O Antigens Phenotype Sequence Analysis DNA Uropathogenic Escherichia coli
Transient computations using the natural stress formulation for solving sharp corner flows
In this short communication, we analyse the potential of the natural stress formulation (NSF) (i.e. aligning the stress basis along streamlines) for computing planar flows of an Oldroyd-B fluid around sharp corners. This is...
Sharp high-frequency estimates for the Helmholtz equation and applications to boundary integral equations
We consider three problems for the Helmholtz equation in interior and
exterior domains in R^d, (d = 2, 3): the exterior Dirichlet-to-Neumann and Neumann-to-Dirichlet problems for outgoing solutions, and the interior...
exterior domains in R^d, (d = 2, 3): the exterior Dirichlet-to-Neumann and Neumann-to-Dirichlet problems for outgoing solutions, and the interior...
Sharp turns and gyrotaxis modulate surface accumulation of microorganisms.
The accumulation of swimming microorganisms at surfaces is an essential feature of various physical, chemical, and biological processes in confined spaces. To date, this accumulation is mainly assumed to depend on the change of...
Decomposing the Humanities
S Connor
Feb 07, 2017
Drawing deeply from the example of Michel Serres, Bruno Latour’s work represents a critique of the commitment to critique which has become the dominant mode of much work in the humanities. Latour’s An Inquiry into Modes of...
Sharp high-frequency estimates for the Helmholtz equation and applications to boundary integral equations
We consider three problems for the Helmholtz equation in interior and
exterior domains in R^d, (d = 2, 3): the exterior Dirichlet-to-Neumann and Neumann-to-Dirichlet problems for outgoing solutions, and the interior...
exterior domains in R^d, (d = 2, 3): the exterior Dirichlet-to-Neumann and Neumann-to-Dirichlet problems for outgoing solutions, and the interior...
Impaired spatial learning and suppression of sharp wave ripples by cholinergic activation at the goal location.
The hippocampus plays a central role in long-term memory formation, and different hippocampal network states are thought to have different functions in this process. These network states are controlled by neuromodulatory inputs...
Towards the Homotopy Type of the Morse Complex
Connor Donovan
Jan 01, 0001
Mathematicians have long been interested in studying the properties of simplicial complexes. In 1998, Robin Forman developed gradient vector fields as a tool to study these complexes. Having gradient vector fields to study these...
Discrete Morse Theory Morse complex simplicial complex Strong Collapsibility Geometry and Topology mathematics Physical Sciences and Mathematics
Published by: Ursinus College
Characterizing the Interaction of MAGUK Scaffold Protein PSD-95 With Synaptic Adhesion Protein Slitrk2
Connor Loomis
Jan 01, 0001
In the developing nervous system, synapse formation is crucial to establish proper brain wiring and therefore function. At synapses, several pre- and postsynaptic adhesion proteins are expressed to coordinate synapse formation....
synapse formation postsynaptic adhesion proteins Slitrk2 MAGUK scaffold proteins PSD-95 yeast two-hybrid assay Biology Cell Biology Life Sciences Molecular and Cellular Neuroscience
Published by: Ursinus College
Communicating Climate to Ourselves and Others
Connor Bernier
Jan 01, 0001
My Summer Fellows experience has focused on the essential importance of communication in the climate crisis, and on personal exploration to reconnect with the natural world. Grounding practices such as hiking in the woods and...
Climate Communication frameworks autoethnography Social Media Valley Forge Chanticleer communication Environmental Studies
Published by: Ursinus College
The Three Billy Goats Gruff
Connor Renfroe
Jan 01, 0001
A prose story
Anthology Winthrop Literary Journal Arts Journal Arts Magazine Literary Magazine Magazine art poetry prose Creative Writing fiction
Published by: Winthrop University
Sharp bounds on Helmholtz impedance-to-impedance maps and application to overlapping domain decomposition
We prove sharp bounds on certain impedance-to-impedance maps (and their compositions) for the Helmholtz equation with large wavenumber (i.e., at high frequency) using semiclassical defect measures. Gong et al. (Numer. Math....
Sharp Second-Order Pointwise Asymptotics for Lossless Compression with Side Information.
The problem of determining the best achievable performance of arbitrary lossless compression algorithms is examined, when correlated side information is available at both the encoder and decoder. For arbitrary source-side...
Impaired spatial learning and suppression of sharp wave ripples by cholinergic activation at the goal location
The hippocampus plays a central role in long-term memory formation, and different hippocampal network states are thought to have different functions in this process. These network states are controlled by neuromodulatory inputs...
Penalized smoothing splines resolve the curvature identifiability problem in age-period-cohort models with unequal intervals
Age-period-cohort (APC) models are frequently used in a variety of health and demographic-related outcomes. Fitting and interpreting APC models to data in equal intervals (equal age and period widths) is nontrivial due to the...
Sharp bounds on Helmholtz impedance-to-impedance maps and application to overlapping domain decomposition
We prove sharp bounds on certain impedance-to-impedance maps (and their compositions) for the Helmholtz equation with large wavenumber (i.e., at high frequency) using semiclassical defect measures. Gong et al. (Numer. Math....
Penalized smoothing splines resolve the curvature identifiability problem in age-period-cohort models with unequal intervals
Age-period-cohort (APC) models are frequently used in a variety of health and demographic-related outcomes. Fitting and interpreting APC models to data in equal intervals (equal age and period widths) is nontrivial due to the...
Choralities
STEVEN CONNOR
Oct 22, 2015
A Discrete Morse Approach for Computing Homotopy Types: An Exploration of the Morse, Generalized Morse, Matching, and Independence Complexes
Connor Donovan
Jan 01, 0001
In this thesis, we study possible homotopy types of four families of simplicial complexes-the Morse complex, the generalized Morse complex, the matching complex, and the independence complex-using discrete Morse theory. Given a...
Morse complex matchings strong collapses homotopy type chord diagrams Geometry and Topology mathematics Physical Sciences and Mathematics
Published by: Ursinus College
Yeast: The Gateway to Redefining and Improving Biology Labs
Connor Loomis
Jan 01, 0001
Building off of collegiate research performed during the summer of 2018, this lesson plan outlines a lab for secondary students using yeast. Yeast is an affordable and convenient organism to introduce to secondary education, and...
Lesson plans yeast growth secondary education lab protocols biology learning standards Data Collection Data analysis primary scientific literature Biology Cell Biology Curriculum and Instruction Educational Assessment, Evaluation, and Research Educational Methods Science and Mathematics Education secondary education
Published by: Ursinus College
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