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Resource Allocation for Epidemic Control Across Multiple Sub-populations.
The number of pathogenic threats to plant, animal and human health is increasing. Controlling the spread of such threats is costly and often resources are limited. A key challenge facing decision makers is how to allocate...
Comprehension, Perception, and Projection
Health social networks (HSNs) allow individuals with health information needs to connect and discuss health-related issues online. Political-technology intertwinement (e.g. GDPR and Digital Technology) highlights that users need...
Published by: IGI Global Scientific Publishing
End Users' Initial Perceptions of mHealth in Nigeria
Mobile health (mHealth) is perceived as a “silver bullet” solution to many of the existing healthcare delivery issues in developing regions. However, the design, development, piloting, implementation, and maintenance activities...
Published by: IGI Global Scientific Publishing
Maternal-to-fetal allopurinol transfer and xanthine oxidase suppression in the late gestation pregnant rat.
Andrew D Kane, Emily J Camm, Hans G Richter, Ciara Lusby, Deodata Tijsseling, Joepe J Kaandorp, Jan B Derks, Susan E Ozanne, Dino A Giussani
Aug 12, 2020
Fetal brain hypoxic injury remains a concern in high-risk delivery. There is significant clinical interest in agents that may diminish neuronal damage during birth asphyxia, such as in allopurinol, an inhibitor of the prooxidant...
Preference uncertainty accounts for developmental effects on susceptibility to peer influence in adolescence
Andrea M. F. Reiter, Michael Moutoussis, Lucy Vanes, Rogier Kievit, Edward T. Bullmore, Ian M. Goodyer, Peter Fonagy, Peter B. Jones, Raymond J. Dolan, Edward Bullmore, Raymond Dolan, Ian Goodyer, Peter Jones, Tobias Hauser, Sharon Neufeld, Rafael Romero-Garcia, Michelle St Clair, Petra Vértes, Kirstie Whitaker, Becky Inkster, Gita Prabhu, Cinly Ooi, Umar Toseeb, Barry Widmer, Junaid Bhatti, Laura Villis, Ayesha Alrumaithi, Sarah Birt, Aislinn Bowler, Kalia Cleridou, Hina Dadabhoy, Emma Davies, Ashlyn Firkins, Sian Granville, Elizabeth Harding, Alexandra Hopkins, Daniel Isaacs, Janchai King, Danae Kokorikou, Christina Maurice, Cleo McIntosh, Jessica Memarzia, Harriet Mills, Ciara O’Donnell, Sara Pantaleone, Jenny Scott, Matilde Vaghi, Anne-Laura van Harmelen, Andrea Reiter
Jun 22, 2021
Moving through Motherhood
Victoria E Salmon, Lauren R Rodgers, Peter Rouse, Oli Williams, Emma Cockcroft, Kate Boddy, Luana De Giorgio, Ciara Thomas, Charlie Foster, Rosie Davies, Kelly Morgan, Rachel Jarvie, Christina Weis, Richard M Pulsford
Apr 24, 2021
Information received by women regarding physical activity during and after pregnancy often lacks clarity and may be conflicting and confusing. Without clear, engaging, accessible guidance centred on the experiences of pregnancy...
The Grizzly, April 26, 2001
Lauren Cyrsky, Dan Reimold, Patricia Quinn, Quinn Dinsmore, Cara Nageli, Krista Bailey, Christina Abreu, Brian Berg, Travis Roop, Chris Fox, Padraic Maroney, Ciara Rodgers, Becky Borbidge, Susan Patton, Sarah Napolitan
Jan 01, 0001
Watson Foundation Considers Ursinus for Membership Dining Committee Addresses Rising Number of Student Complaints Senior Student Young Named Ursinus Valedictorian CAB, RHA, USGA, and Class Officer Elections Being Held ...
Ursinus College Collegeville Pennsylvania newspaper Floy Lewis Bakes Center STDs track team baseball tennis softball lacrosse Wismer dining hall Melissa Young student government Watson Foundation cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Emergence of a globally dominant IncHI1 plasmid type associated with multiple drug resistant typhoid.
Kathryn E Holt, Minh Duy Phan, Stephen Baker, Pham Thanh Duy, Tran Vu Thieu Nga, Satheesh Nair, A Keith Turner, Ciara Walsh, Séamus Fanning, Sinéad Farrell-Ward, Shanta Dutta, Sam Kariuki, François-Xavier Weill, Julian Parkhill, Gordon Dougan, John Wain
Sep 06, 2019
Typhoid fever, caused by Salmonella enterica serovar Typhi (S. Typhi), remains a serious global health concern. Since their emergence in the mid-1970s multi-drug resistant (MDR) S. Typhi now dominate drug sensitive equivalents...
Towards onset prevention of cognition decline in adults with Down syndrome (The TOP-COG study)
Analysis of pit latrine microbiota reveals depth-related variation in composition, and key parameters and taxa associated with latrine fill-up rate.
Modeling and Rescue of RP2 Retinitis Pigmentosa Using iPSC-Derived Retinal Organoids
Amelia Lane, Katarina Jovanovic, Ciara Shortall, Daniele Ottaviani, Anna Brugulat-Panes, Nele Schwarz, Rosellina Guarascio, Matthew J Hayes, Arpad Palfi, Naomi Chadderton, G Jane Farrar, Alison J Hardcastle, Michael E Cheetham
Jul 07, 2020
RP2 mutations cause a severe form of X-linked retinitis pigmentosa (XLRP). The mechanism of RP2-associated retinal degeneration in humans is unclear, and animal models of RP2 XLRP do not recapitulate this severe phenotype. Here...
AAV CRISPR gene editing Cell Death Disease Modeling gene therapy Genetic inherited disease Retinal Degeneration retinal organoid stem cell Cell Death Cell Survival Dependovirus GTP-Binding Proteins Gene Expression Regulation Gene Knockdown Techniques Humans Induced Pluripotent Stem Cells Membrane Proteins Models Biological Organoids Retina Retinal Rod Photoreceptor Cells Retinitis Pigmentosa
Analysis of pit latrine microbiota reveals depth-related variation in composition, and key parameters and taxa associated with latrine fill-up rate.
Umer Zeeshan Ijaz, Ozan Gundogdu, Ciara Keating, Miriam van Eekert, Walter Gibson, Julian Parkhill, Faraji Abilahi, Benard Liseki, Viet-Anh Nguyen, Steven Sudgen, Christopher Quince, Jeroen HJ Ensink, Belen Torondel, Alan W Walker
Nov 09, 2022
Pit latrines are used by billions of people globally, often in developing countries where they provide a low-tech and low-cost sanitation method. However, health and social problems can arise from a lack of emptying or...
Divergence of mechanistic pathways mediating cardiovascular aging and developmental programming of cardiovascular disease.
Maternal Allopurinol Prevents Cardiac Dysfunction in Adult Male Offspring Programmed by Chronic Hypoxia During Pregnancy.
Youguo Niu, Andrew D Kane, Ciara M Lusby, Beth J Allison, Yi Yi Chua, Joepe J Kaandorp, Rhiannon Nevin-Dolan, Thomas J Ashmore, Heather L Blackmore, Jan B Derks, Susan E Ozanne, Dino A Giussani
Sep 05, 2018
allopurinol developmental programming Hypoxia Oxidative Stress Pregnancy Rats allopurinol Animals Enzyme Inhibitors Female Heart Failure Heart Function Tests Hypoxia Male Myocardial Contraction Oxidative Stress Pregnancy Pregnancy Complications Rats Receptor Muscarinic M2 Receptors Adrenergic beta Sarcoplasmic Reticulum Calcium-Transporting ATPases sympathetic nervous system xanthine oxidase
Using genetic variation to disentangle the complex relationship between food intake and health outcomes.
Nicola Pirastu, Ciara McDonnell, Eryk J Grzeszkowiak, Ninon Mounier, Fumiaki Imamura, Jordi Merino, Felix Day, Jie Zheng, Nele Taba, Maria Pina Concas, Linda Repetto, Katherine Kentistou, Antonietta Robino, Tõnu Esko, Peter K Joshi, Krista Fischer, Kenneth Ong, Tom R Gaunt, Zoltán Kutalik, John RB Perry, James F Wilson
Jun 07, 2022
Diet is considered as one of the most important modifiable factors influencing human health, but efforts to identify foods or dietary patterns associated with health outcomes often suffer from biases, confounding, and reverse...
Commentary on the use of the reproduction number R during the COVID-19 pandemic.
Carolin Vegvari, Sam Abbott, Frank Ball, Ellen Brooks-Pollock, Robert Challen, Benjamin S Collyer, Ciara Dangerfield, Julia R Gog, Katelyn M Gostic, Jane M Heffernan, T Déirdre Hollingsworth, Valerie Isham, Eben Kenah, Denis Mollison, Jasmina Panovska-Griffiths, Lorenzo Pellis, Michael G Roberts, Gianpaolo Scalia Tomba, Robin N Thompson, Pieter Trapman
Sep 11, 2022
A nebulised antitumour necrosis factor receptor-1 domain antibody in patients at risk of postoperative lung injury
James Ryan, Andrew I Bayliffe, Daniel F McAuley, Joyce Yeung, David R Thickett, Phillip A Howells, Ciara O'Donnell, Arlette M Vassallo, Tracey J Wright, Elizabeth McKie, Kelly Hardes, Charlotte Summers, Martin O Shields, William Powley, Robert Wilson, Aili L Lazaar, Andrew Fowler, Gavin D Perkins
Nov 20, 2020
BACKGROUND: Tumour necrosis factor receptor 1 (TNFR1) signalling mediates the cell death and inflammatory effects of TNF-α. OBJECTIVE: The current clinical trial investigated the effects of a nebulised TNFR1 antagonist...
Predictors of pathological complete response to neoadjuvant treatment and changes to post-neoadjuvant HER2 status in HER2-positive invasive breast cancer.
Ayaka Katayama, Islam M Miligy, Sho Shiino, Michael S Toss, Karim Eldib, Sasagu Kurozumi, Cecily M Quinn, Nahla Badr, Ciara Murray, Elena Provenzano, Grace Callagy, Cian Martyn, Rebecca Millican-Slater, Colin Purdie, Dave Purnell, Sarah E Pinder, Tetsunari Oyama, Abeer M Shaaban, Ian Ellis, Andrew HS Lee, Emad A Rakha
Jun 22, 2021
The response of human epidermal growth factor receptor2 (HER2)- positive breast cancer (BC) patients to anti-HER2 targeted therapy is significant. However, the response is not uniform and a proportion of HER2-positive patients...
Retrospective observational study of HER2 immunohistochemistry in borderline breast cancer patients undergoing neoadjuvant therapy, with an emphasis on Group 2 (HER2/CEP17 ratio ≥2.0, HER2 copy number <4.0 signals/cell) cases.
Emad A Rakha, Islam M Miligy, Cecily M Quinn, Elena Provenzano, Abeer M Shaaban, Caterina Marchiò, Michael S Toss, Grace Gallagy, Ciara Murray, Janice Walshe, Ayaka Katayama, Karim Eldib, Nahla Badr, Bruce Tanchel, Rebecca Millican-Slater, Colin Purdie, Dave Purnell, Sarah E Pinder, Ian O Ellis, Andrew HS Lee
May 25, 2021
BACKGROUND: The ASCO/CAP guidance on HER2 testing in breast cancer (BC) has recently changed. Group 2 tumours with immunohistochemistry score 2+ and HER2/CEP17 ratio ≥2.0 and HER2 copy number <4.0 signals/cell were re-classified...
The Grizzly, February 29, 2000
Stephanie Restine, Emily Callaghan, Dan Reimold, Sean Killeen, Lauren Flanagan, Cynthia Neff, Ciara Rodgers, Debora Sarmento, Matthew James Terenna, Jeff Church, Kevin Wilson, Stephanie Ott, Diane Johnson, Andy Owens, Fran Shaughnessy, John Grebe, Heather W. Gurk
Jan 01, 0001
Phi Psi Sanctioned UC Students Weather Winter Sickness Meghan Gualtieri: Profile of a True UC Role Model Ursinus' Own Superbagger GOP Race Tightens in Michigan and Arizona Investors to Transform Mir Into Out-of-this-World...
Ursinus College Collegeville Pennsylvania newspaper Basketball Yori Adegunwa gymnastics track team Bill Stiles Berman Art Museum ProTheatre Diversity Wismer dining hall Meghan Gualtieri Susan Goll Phi Alpha Psi pledging flu cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
The Grizzly, April 5, 2001
Lauren Cyrsky, Dan Reimold, Anne Antanavage, '04, Tammy Scherer, Krista Bailey, Leah Miller, Thomas Lipschultz, Aaron Ranck, Kelly Tessena, Susan Patton, Sarah Napolitan, Jeff Church, Ciara Rodgers, Jenn Barnes, Kate Gallagher, Padraic Maroney
Jan 01, 0001
Three National Greek Organizations Approved by Faculty Residence Life to Close Clamer Hall in Fall Semester Five-a-day Challenge for Healthy Eating Presented by Nutrition Expert Senior Class Gift now up to Individual Airband...
Ursinus College Collegeville Pennsylvania newspaper golf tennis Peter Gallagher softball track team lacrosse baseball campus sculptures fraternities sororities Jeff Church Airband Clamer Hall cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
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