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Cellulose Acetate Microbeads for Controlled Delivery of Essential Micronutrients
Ciarán Callaghan, Davide Califano, Marcos Henrique Feresin Gomes, Hudson Wallace Pereira de Carvalho, Karen J. Edler, Davide Mattia
Mar 27, 2023
The controlled delivery of micronutrients to soil and plants is essential to increase agricultural yields. However, this is today achieved using fossil fuel-derived plastic carriers, posing environmental risks and...
Cellulose Acetate Microbeads for Controlled Delivery of Essential Micronutrients
Ciarán Callaghan, Davide Califano, Marcos Henrique Feresin Gomes, Hudson Wallace Pereira de Carvalho, Karen J. Edler, Davide Mattia
Mar 27, 2023
The controlled delivery of micronutrients to soil and plants is essential to increase agricultural yields. However, this is today achieved using fossil fuel-derived plastic carriers, posing environmental risks and...
Detecting Sequential Genre Change in Eighteenth-Century Texts
Machine classification of historical books into genres is a common task for NLP-based classifiers and has a number of applications, from literary analysis to information retrieval. However it is not a straightforward task, as...
Medical Biotechnology- Point of Care devices and Artificial Intelligence
Natalya Callaghan
Jan 01, 0001
Point of care devices are a biotechnology product that produce individual diagnostic tests within minutes to better assess individual patient needs. These risk assessments for numerous conditions can use the help of algorithms...
Published by: Harrisburg University of Science and Technology
Detecting Sequential Genre Change in Eighteenth-Century Texts
Machine classification of historical books into genres is a common task for NLP-based classifiers and has a number of applications, from literary analysis to information retrieval. However it is not a straightforward task, as...
The use of third-party packed red blood cells during ex situ normothermic machine perfusion of organs for transplantation
Chris J Callaghan, Benedict L Phillips, Theodora Foukaneli, Susan Robinson, Christopher JE Watson
Oct 05, 2020
Ex situ normothermic machine perfusion (NMP) is being used increasingly in the assessment of higher risk deceased donor organs and to facilitate prolonged organ storage. Third-party packed red blood cells (pRBCs) are often used...
Improving public health evaluation
BACKGROUND: In 2011, the House of Lords published a report on Behaviour Change, in which they report that "a lot more could, and should, be done to improve the evaluation of interventions." This study aimed to undertake a needs...
The crystal structure of Trz1, the long form RNase Z from yeast.
Miao Ma, Ines Li de la Sierra-Gallay, Noureddine Lazar, Olivier Pellegrini, Dominique Durand, Anita Marchfelder, Ciarán Condon, Herman van Tilbeurgh
Aug 20, 2021
tRNAs are synthesized as precursor RNAs that have to undergo processing steps to become functional. Yeast Trz1 is a key endoribonuclease involved in the 3΄ maturation of tRNAs in all domains of life. It is a member of the...
Amino Acid Sequence Catalytic Domain Conserved Sequence Crystallography X-Ray Endoribonucleases evolution Molecular Models Molecular Open Reading Frames Protein Conformation Protein Domains RNA Transfer Recombinant Fusion Proteins Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins Sequence Alignment Sequence Homology Amino Acid
Response to "Past, Present, and Future of Dynamic Kidney and Liver Preservation and Resuscitation"
We are writing in response to the article written by Jochmans et al [1]. The article is a comprehensive review on the status of preservation and resuscitation techniques in kidney and liver transplantation. It highlights the...
A breaking internal wave in the surface ocean boundary layer
High-temporal resolution measurements in the Labrador Sea surface layer are presented using an upwardly-profiling autonomous microstructure instrument, which captures an internal wave in the act of breaking at the base of the...
A breaking internal wave in the surface ocean boundary layer
High-temporal resolution measurements in the Labrador Sea surface layer are presented using an upwardly-profiling autonomous microstructure instrument, which captures an internal wave in the act of breaking at the base of the...
Protocol of a randomised controlled, open-label trial of ex vivo normothermic perfusion versus static cold storage in donation after circulatory death renal transplantation.
TRANSPLANT SURGERY Adolescent Adult Aged Cold Temperature Cryopreservation Delayed Graft Function Fibrosis Graft Rejection Humans Immunosuppressive Agents Kidney Kidney Transplantation Length of Stay Middle Aged Organ Preservation Organ Preservation Solutions Perfusion Renal Dialysis Treatment Outcome Young Adult
Solid Organ Transplantation From Deceased Donors With Infective Endocarditis
George HB Greenhall, Matthew L Robb, Chloe Brown, Rachel J Johnson, Laurie A Tomlinson, Chris J Callaghan, Christopher JE Watson
May 03, 2021
BACKGROUND: There is little evidence regarding the use of organs from deceased donors with infective endocarditis. We performed a retrospective analysis of the utilization, safety, and long-term survival of transplants from...
Structures of B. subtilis Maturation RNases Captured on 50S Ribosome with Pre-rRNAs.
Stephanie Oerum, Tom Dendooven, Marjorie Catala, Laetitia Gilet, Clément Dégut, Aude Trinquier, Maxime Bourguet, Pierre Barraud, Sarah Cianferani, Ben F Luisi, Ciarán Condon, Carine Tisné
Jan 06, 2021
The pathways for ribosomal RNA (rRNA) maturation diverge greatly among the domains of life. In the Gram-positive model bacterium, Bacillus subtilis, the final maturation steps of the two large ribosomal subunit (50S) rRNAs, 23S...
Spinal Cord Ischemia in Pancreas Transplantation
Benedict L Phillips, Georgios Papadakis, Rachel Bell, Sanjay Sinha, Chris J Callaghan, Murat Akyol, Christopher JE Watson, Martin Drage
Nov 15, 2019
BACKGROUND: Spinal cord ischemia (SCI) is a rare but devastating condition that can occur in the perioperative period resulting in paraplegia. Although diabetes mellitus is a risk factor for SCI in other types of major surgery...
Stable cellulose nanofibril microcapsules from Pickering emulsion templates
Hui Shi Huishi, Kazi M.Zakir Hossain, Davide Califano, Ekanem Ekanem, Ciaran Callaghan, Janet L Scott, Davide Mattia, Karen Edler
Mar 22, 2022
Electrostatic attractions are essential in any complex formation between the nanofibrils of the opposite charge for a specific application, such as microcapsule production. Here, we used cationized cellulose nanofibril...
Laboratory investigation of the Bruun Rule and beach response to sea level rise
Alexander L. Atkinson, Tom E. Baldock, Florent Birrien, David P. Callaghan, Peter Nielsen, Tomas Beuzen, Ian L. Turner, Chris E. Blenkinsopp, Roshanka Ranasinghe
Jun 01, 2018
Rising sea levels are expected to cause widespread coastal recession over the course of the next century. In this work, new insight into the response of sandy beaches to sea level rise is obtained through a series of...
Donor-Transmitted Cancer in Orthotopic Solid Organ Transplant Recipients
George H B Greenhall, Maria Ibrahim, Utkarsh Dutta, Carolyn Doree, Susan J Brunskill, Rachel J Johnson, Laurie A Tomlinson, Chris J Callaghan, Christopher J E Watson
Mar 28, 2022
Donor-transmitted cancer (DTC) has major implications for the affected patient as well as other recipients of organs from the same donor. Unlike heterotopic transplant recipients, there may be limited treatment options for...
Lactonic Sophorolipids Increase Tumor Burden in Apcmin+/- Mice.
Breedge Callaghan, Helen Lydon, Sophie LKW Roelants, Inge NA Van Bogaert, Roger Marchant, Ibrahim M Banat, Christopher A Mitchell
May 03, 2018
Sophorolipids (SL) are amphiphilic biosurfactant molecules consisting of a disaccharide sophorose with one fatty acid at the C1 position and optional acetylation at the C6'and C6" positions. They exist in a closed ring lactonic...
Application of Metaheuristic Approaches for the Variable Selection Problem
Variable selection is an old topic from regression models. Besides many conventional approaches, some metaheuristic approaches from the realm of optimization such as GA (Genetic Algorithm) or simulated annealing have been...
Published by: IGI Global Scientific Publishing
A Re-evaluation of Discarded Deceased Donor Kidneys in the UK
Shruti Mittal, Anna Adamusiak, Catherine Horsfield, Ioannis Loukopoulos, Nikolaos Karydis, Nicos Kessaris, Martin Drage, Jonathon Olsburgh, Christopher JE Watson, Chris J Callaghan
Nov 28, 2017
BACKGROUND: A significant proportion of procured deceased donor kidneys are subsequently discarded. The UK Kidney Fast-Track Scheme (KFTS) was introduced in 2012, enabling kidneys at risk of discard to be simultaneously offered...
Adult Aged Aged 80 and over Cause of Death Decision Support Techniques Donor Selection Female Graft Survival Humans Kidney Transplantation Male Middle Aged Postoperative Complications Predictive Value of Tests Program Evaluation Risk Assessment Risk Factors Time Factors Tissue Donors Tissue and Organ Procurement Treatment Outcome United Kingdom
Stable cellulose nanofibril microcapsules from Pickering emulsion templates
Hui Shi Huishi, Kazi M.Zakir Hossain, Davide Califano, Ekanem Ekanem, Ciaran Callaghan, Janet L Scott, Davide Mattia, Karen Edler
Mar 22, 2022
Electrostatic attractions are essential in any complex formation between the nanofibrils of the opposite charge for a specific application, such as microcapsule production. Here, we used cationized cellulose nanofibril...
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