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Patient experience of supported computerized CBT in an inner-city IAPT service
Computerized cognitive behavioural therapy (cCBT) has been developed to address economic and clinical issues around limited access to evidence-based therapy. Supported cCBT (variously termed iCBT or eCBT) has been developed...
Patient experience of supported computerized CBT in an inner-city IAPT service
Computerized cognitive behavioural therapy (cCBT) has been developed to address economic and clinical issues around limited access to evidence-based therapy. Supported cCBT (variously termed iCBT or eCBT) has been developed...
Self-organisation and convection of confined magnetotactic bacteria.
Albane Théry, Lucas Le Nagard, Jean-Christophe Ono-Dit-Biot, Cécile Fradin, Kari Dalnoki-Veress, Eric Lauga
Oct 19, 2020
Collective motion is found at all scales in biological and artificial systems, and extensive research is devoted to describing the interplay between interactions and external cues in collective dynamics. Magnetotactic bacteria...
Parameterised branching processes
Let (Zn,n≥0) be a supercritical Galton–Watson process whose offspring distribution μ has mean λ>1 and is such that ∫xlog+(x)dμ(x)<+∞. According to the famous Kesten & Stigum theorem...
Bottleneck genes and community structure in the cell cycle network of S. pombe.
The identification of cell cycle-related genes is still a difficult task, even for organisms with relatively few genes such as the fission yeast. Several gene expression studies have been published on S. pombe showing...
Symbolic transfer entropy reveals the age structure of pandemic influenza transmission from high-volume influenza-like illness data.
Existing methods to infer the relative roles of age groups in epidemic transmission can normally only accommodate a few age classes, and/or require data that are highly specific for the disease being studied. Here, symbolic...
A sprouting tree model for random boolean functions
We define a new probability distribution for Boolean functions of k variables. Consider the random Binary Search Tree of size n, and label its internal nodes by connectives and its leaves by variables or their negations. This...
A sprouting tree model for random boolean functions
We define a new probability distribution for Boolean functions of k variables. Consider the random Binary Search Tree of size n, and label its internal nodes by connectives and its leaves by variables or their negations. This...
Parameterised branching processes
Let (Zn,n≥0) be a supercritical Galton–Watson process whose offspring distribution μ has mean λ>1 and is such that ∫xlog+(x)dμ(x)<+∞. According to the famous Kesten & Stigum theorem...
Lockdown as a last resort option in case of COVID-19 epidemic rebound
Cécile Tran Kiem, Pascal Crépey, Paolo Bosetti, Daniel Levy Bruhl, Yazdan Yazdanpanah, Henrik Salje, Pierre-Yves Boëlle, Simon Cauchemez
Jun 28, 2021
BackgroundGiven its high economic and societal cost, policymakers might be reluctant to implement a large-scale lockdown in case of coronavirus disease (COVID-19) epidemic rebound. They may consider it as a last resort option if...
A novel CISD2 mutation associated with a classical Wolfram syndrome phenotype alters Ca2+ homeostasis and ER-mitochondria interactions.
Cécile Rouzier, David Moore, Cécile Delorme, Sandra Lacas-Gervais, Samira Ait-El-Mkadem, Konstantina Fragaki, Florence Burté, Valérie Serre, Sylvie Bannwarth, Annabelle Chaussenot, Martin Catala, Patrick Yu-Wai-Man, Véronique Paquis-Flucklinger
Jun 28, 2018
Wolfram syndrome (WS) is a progressive neurodegenerative disease characterized by early-onset optic atrophy and diabetes mellitus, which can be associated with more extensive central nervous system and endocrine complications....
Divergent Catalytic Strategies for the Cis/Trans Stereoselective Ring-Opening Polymerization of a Dual Cyclic Carbonate/Olefin Monomer
A dual seven-membered cyclic carbonate/olefin monomer was synthesized from CO2 and cis-1,4-butenediol and polymerized. The properties of the polymer were controlled using divergent catalytic strategies toward the stereochemistry...
Associations with intraocular pressure across Europe
Anthony P Khawaja, Henriët Springelkamp, Catherine Creuzot-Garcher, Cécile Delcourt, Albert Hofman, René Höhn, Adriana I Iglesias, Roger CW Wolfs, Jean-François Korobelnik, Rufino Silva, Fotis Topouzis, Katie M Williams, Alain M Bron, Gabriëlle HS Buitendijk, Maria da Luz Cachulo, Audrey Cougnard-Grégoire, Jean-François Dartigues, Christopher J Hammond, Norbert Pfeiffer, Angeliki Salonikiou, Cornelia M van Duijn, Johannes R Vingerling, Robert N Luben, Alireza Mirshahi, Julia Lamparter, Caroline CW Klaver, Nomdo M Jansonius, Paul J Foster, European Eye Epidemiology (E³) Consortium
Sep 29, 2016
Divergent Catalytic Strategies for the Cis/Trans Stereoselective Ring-Opening Polymerization of a Dual Cyclic Carbonate/Olefin Monomer
A dual seven-membered cyclic carbonate/olefin monomer was synthesized from CO2 and cis-1,4-butenediol and polymerized. The properties of the polymer were controlled using divergent catalytic strategies toward the stereochemistry...
Specific effect of a dopamine partial agonist on counterfactual learning
Alexandre Salvador, Yulia Worbe, Cécile Delorme, Giorgio Coricelli, Raphaël Gaillard, Trevor W Robbins, Andreas Hartmann, Stefano Palminteri
Apr 12, 2018
The dopamine partial agonist aripiprazole is increasingly used to treat pathologies for which other antipsychotics are indicated because it displays fewer side effects, such as sedation and depression-like symptoms, than other...
A comprehensive assessment of demographic, environmental, and host genetic associations with gut microbiome diversity in healthy individuals.
Petar Scepanovic, Flavia Hodel, Stanislas Mondot, Valentin Partula, Allyson Byrd, Christian Hammer, Cécile Alanio, Jacob Bergstedt, Etienne Patin, Mathilde Touvier, Olivier Lantz, Matthew L Albert, Darragh Duffy, Lluis Quintana-Murci, Jacques Fellay, Milieu Intérieur Consortium
Feb 07, 2020
BACKGROUND: The gut microbiome is an important determinant of human health. Its composition has been shown to be influenced by multiple environmental factors and likely by host genetic variation. In the framework of the Milieu...
Tectonic and climatic drivers of Asian monsoon evolution.
James R Thomson, Philip B Holden, Pallavi Anand, Neil R Edwards, Cécile A Porchier, Nigel BW Harris
Aug 02, 2021
Asian Monsoon rainfall supports the livelihood of billions of people, yet the relative importance of different drivers remains an issue of great debate. Here, we present 30 million-year model-based reconstructions of Indian...
Evaluating the impact of curfews and other measures on SARS-CoV-2 transmission in French Guiana.
Alessio Andronico, Cécile Tran Kiem, Juliette Paireau, Tiphanie Succo, Paolo Bosetti, Noémie Lefrancq, Mathieu Nacher, Félix Djossou, Alice Sanna, Claude Flamand, Henrik Salje, Cyril Rousseau, Simon Cauchemez
May 10, 2021
While general lockdowns have proven effective to control SARS-CoV-2 epidemics, they come with enormous costs for society. It is therefore essential to identify control strategies with lower social and economic impact. Here, we...
How do i bite thee? let me count the ways
Rebecca C Christofferson, Helen J Wearing, Erik A Turner, Christine S Walsh, Henrik Salje, Cécile Tran-Kiem, Simon Cauchemez
Nov 04, 2022
In models of mosquito-borne transmission, the mosquito biting rate is an influential parameter, and understanding the heterogeneity of the process of biting is important, as biting is usually assumed to be relatively homogeneous...
The interactome of KRAB zinc finger proteins reveals the evolutionary history of their functional diversification.
Pierre-Yves Helleboid, Moritz Heusel, Julien Duc, Cécile Piot, Christian W Thorball, Andrea Coluccio, Julien Pontis, Michaël Imbeault, Priscilla Turelli, Ruedi Aebersold, Didier Trono
Dec 12, 2019
Krüppel-associated box (KRAB)-containing zinc finger proteins (KZFPs) are encoded in the hundreds by the genomes of higher vertebrates, and many act with the heterochromatin-inducing KAP1 as repressors of transposable elements...
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