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Fault Recognition for Mechanical Arm by Using Relative Margin SVM
Dongzhe Yang
Apr 01, 2022
Monitoring and detecting faults during the operation of the manipulator is the prerequisite for fault recognition and safe operation. Accurate classification of mechanical arm faults can support to effectively eliminate...
Systems & Software Design Computer Science and Information Technology Systems and Software Engineering
Published by: IGI Global Scientific Publishing
On Gap-Based Lower Bounding Techniques for Best-Arm Identification.
In this paper, we consider techniques for establishing lower bounds on the number of arm pulls for best-arm identification in the multi-armed bandit problem. While a recent divergence-based approach was shown to provide...
Contributions of the non-kicking-side arm to rugby place-kicking technique
To investigate non-kicking-side arm motion during rugby place kicking, five experienced male kickers performed trials under two conditions, both with an accuracy requirement but one with an additional maximal distance demand....
Designs for adding a treatment arm to an ongoing clinical trial.
BACKGROUND:For many disease areas, there are often treatments in different stages of the development process. We consider the design of a two-arm parallel group trial where it is planned to add a new experimental treatment arm...
Optimal allocation multiple testing adaptive design Adding A Treatment Arm Family-wise Error Rate Control
Published by: Trials
Contributions of the non-kicking-side arm to rugby place-kicking technique
To investigate non-kicking-side arm motion during rugby place kicking, five experienced male kickers performed trials under two conditions, both with an accuracy requirement but one with an additional maximal distance demand....
Controlling type I error rates in multi-arm clinical trials
Multi-arm trials are an efficient way of simultaneously testing several experimental treatments against a shared control group. As well as reducing the sample size required compared to running each trial separately, they have...
An optimised multi-arm multi-stage clinical trial design for unknown variance.
Multi-arm multi-stage trial designs can bring notable gains in efficiency to the drug development process. However, for normally distributed endpoints, the determination of a design typically depends on the assumption that the...
A web application for the design of multi-arm clinical trials.
BACKGROUND: Multi-arm designs provide an effective means of evaluating several treatments within the same clinical trial. Given the large number of treatments now available for testing in many disease areas, it has been argued...
The role of arm movement in early trip recovery in younger and older adults
The aims of this study were to investigate which arm movements are made during trip recovery, to determine the contributions of arm movements in trip recovery and to identify differences in these contributions between younger...
A web application for the design of multi-arm clinical trials
Abstract: Background: Multi-arm designs provide an effective means of evaluating several treatments within the same clinical trial. Given the large number of treatments now available for testing in many disease areas, it has...
A multi-stage drop-the-losers design for multi-arm clinical trials.
Multi-arm multi-stage trials can improve the efficiency of the drug development process when multiple new treatments are available for testing. A group-sequential approach can be used in order to design multi-arm multi-stage...
The role of arm movement in early trip recovery in younger and older adults
The aims of this study were to investigate which arm movements are made during trip recovery, to determine the contributions of arm movements in trip recovery and to identify differences in these contributions between younger...
To add or not to add a new treatment arm to a multiarm study
Multiarm clinical trials, which compare several experimental treatments against control, are frequently recommended due to their efficiency gain. In practise, all potential treatments may not be ready to be tested in a phase...
Deep Learning-Driven Robot Arm Control Fusing Convolutional Visual Perception and Predictive Modeling for Motion Planning
Zhongzhen Yan, Yiming Chang, Lukang Yuan, Feifei Wei, Xianglong Wang, Xinhua Dong, Hongmu Han
Jan 01, 2024
The wide application of robotic technology in various industries from industrial automation to medical assistance is gradually changing our production and lifestyle, and has attracted widespread attention in many fields....
Published by: IGI Global Scientific Publishing
Response-adaptive randomization for multi-arm clinical trials using the forward looking Gittins index rule.
The Gittins index provides a well established, computationally attractive, optimal solution to a class of resource allocation problems known collectively as the multi-arm bandit problem. Its development was originally motivated...
An order restricted multi-arm multi-stage clinical trial design.
One family of designs that can noticeably improve efficiency in later stages of drug development are multi-arm multi-stage (MAMS) designs. They allow several arms to be studied concurrently and gain efficiency by dropping poorly...
Experimental Treatment of Ebola Virus Disease with TKM-130803
Jake Dunning, Foday Sahr, Amanda Rojek, Fiona Gannon, Gail Carson, Baimba Idriss, Thomas Massaquoi, Regina Gandi, Sebatu Joseph, Hassan K Osman, Timothy JG Brooks, Andrew JH Simpson, Ian Goodfellow, Lucy Thorne, Armando Arias, Laura Merson, Lyndsey Castle, Rebecca Howell-Jones, Raul Pardinaz-Solis, Benjamin Hope-Gill, Mauricio Ferri, Jennifer Grove, Mark Kowalski, Kasia Stepniewska, Trudie Lang, John Whitehead, Piero Olliaro, Mohammed Samai, Peter W Horby, RAPIDE-TKM trial team
Jun 13, 2018
BACKGROUND: TKM-130803, a small interfering RNA lipid nanoparticle product, has been developed for the treatment of Ebola virus disease (EVD), but its efficacy and safety in humans has not been evaluated. METHODS AND FINDINGS...
Adult Aged Aged 80 and over Antiviral Agents Ebolavirus Female Hemorrhagic Fever Ebola Host-Pathogen Interactions Humans Infusions Intravenous Male Middle Aged Nanoparticles RNA Small Interfering RNA Viral RNAi Therapeutics Sierra Leone Survival Analysis Time Factors Treatment Outcome Viral Load Young Adult
muLTi-Arm Therapeutic study in pre-ICu patients admitted with Covid-19-Experimental drugs and mechanisms (TACTIC-E)
Ing Ni Lu, Spoorthy Kulkarni, Marie Fisk, Michalis Kostapanos, Edward Banham-Hall, Sonakshi Kadyan, Simon Bond, Sam Norton, Andrew Cope, James Galloway, Frances Hall, David Jayne, Ian B Wilkinson, Joseph Cheriyan
Oct 05, 2020
OBJECTIVES: To determine if a specific intervention reduces the composite of progression of patients with COVID-19-related disease to organ failure or death as measured by time to incidence of any one of the following: death...
Adaptive trial Ambrisentan covid-19 Dapagliflozin EDP1815 Experimental drugs Open-label Protocol randomised controlled trial Benzhydryl Compounds Betacoronavirus covid-19 Coronavirus Infections Glucosides Humans Immunologic Factors Intensive Care Units Pandemics Phenylpropionates Pneumonia Viral Pyridazines Randomized Controlled Trials as Topic Respiration Artificial SARS-CoV-2 Standard of Care COVID-19 Drug Treatment
Repurposed immunomodulatory drugs for Covid-19 in pre-ICu patients - mulTi-Arm Therapeutic study in pre-ICu patients admitted with Covid-19 - Repurposed Drugs (TACTIC-R)
Spoorthy Kulkarni, Marie Fisk, Michalis Kostapanos, Edward Banham-Hall, Simon Bond, Elena Hernan-Sancho, Sam Norton, Joseph Cheriyan, Andrew Cope, James Galloway, Frances Hall, David Jayne, Ian B Wilkinson
Jul 20, 2020
OBJECTIVES: To determine if a specific immunomodulatory intervention reduces progression of COVID-19-related disease to organ failure or death, compared to standard of care (SoC). TRIAL DESIGN: Randomised, parallel 3-arm (1:1:1...
Adaptive trial Baricitinib covid-19 Open-label Protocol randomised controlled trial Ravulizumab Repurposed drugs Antibodies Monoclonal Humanized azetidines Betacoronavirus covid-19 Coronavirus Infections Drug Repositioning Humans Immunologic Factors Intensive Care Units Pandemics Pneumonia Viral Purines Pyrazoles Randomized Controlled Trials as Topic SARS-CoV-2 Sulfonamides COVID-19 Drug Treatment
Self-reference in action
Considerable evidence now shows that making a reference to the self in a task modulates attention, perception, memory, and decision-making. Furthermore, the self-reference effect (SRE) cannot be reduced to domain-general...
Correlates of Balance and Aerobic Indices in Lower-Limb Prostheses Users on Arm Crank Exercise
Background: The HUMAC Balance System (HBS) offers valid measurement of balance, and the arm crank exercise test (ACE) is a valid measure of physiological capacity. Neither have been used to evaluate associations between balance...
Published by: Digital Commons @ Texas A&M University-San Antonio
The influence of leg-to-body ratio, arm-to-body ratio and intra-limb ratio on male human attractiveness.
Human mate choice is influenced by limb proportions. Previous work has focused on leg-to-body ratio (LBR) as a determinant of male attractiveness and found a preference for limbs that are close to, or slightly above, the...
Quantifying Efficiency Gains of Innovative Designs of Two-Arm Vaccine Trials for COVID-19 Using an Epidemic Simulation Model.
Clinical trials of a vaccine during an epidemic face particular challenges, such as the pressure to identify an effective vaccine quickly to control the epidemic, and the effect that time-space-varying infection incidence has on...
ELEVATE - evaluating Temozolomide and Nivolumab in patients with advanced unresectable previously treated oesophagogastric adenocarcinoma with MGMT methylation
Elizabeth Smyth, Kelly Cozens, Daniel Griffiths, Kathryn L Clark, Sean Ewings, Russell Petty, Tim Underwood, Rebecca C Fitzgerald, James Tanner, Olivier Giger, Shubha Anand, Gareth Griffiths
Oct 02, 2022
BACKGROUND: For patients with oesophagogastric adenocarcinoma, surgery is the only curative option and despite the use of multimodality therapy, which combines it with chemotherapy and/or radiotherapy, more than 50% of patients...
Immunotherapy MGMT methylated Oesophagogastric adenocarcinoma Phase II Adenocarcinoma Antineoplastic Combined Chemotherapy Protocols Clinical Trials Phase II as Topic DNA Modification Methylases DNA Repair Enzymes Humans Methylation Neoplasm Recurrence Local Nivolumab Quality of life Temozolomide Tumor Suppressor Proteins
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