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A personalised prosthetic liner with embedded sensor technology
BACKGROUND: Numerous sensing techniques have been investigated in an effort to monitor the main parameters influencing the residual limb/prosthesis interface, fundamental to the optimum design of prosthetic socket solutions....
“He Was the One With the Gun!” Associative Memory for White and Black Faces Seen With Weapons
Much research has found that implicit associations between Black male faces and aggression afect dispositional judgments and decision-making, but there have been few investigations into downstream efects on explicit episodic...
Published by: Digital Commons @ Texas A&M University-San Antonio
A personalised prosthetic liner with embedded sensor technology
BACKGROUND: Numerous sensing techniques have been investigated in an effort to monitor the main parameters influencing the residual limb/prosthesis interface, fundamental to the optimum design of prosthetic socket solutions....
Living in Promiscuity
Alpha-synuclein (α-syn) is a small protein that, in neurons, localizes predominantly to presynaptic terminals. Due to elevated conformational plasticity, which can be affected by environmental factors, in addition to undergoing...
Outcomes and indications for Emergency Thoracotomy after adoption of a more liberal policy in a western European level 1 Trauma Center
Edoardo Segalini, Luca Di Donato, Arianna Birindelli, Alice Piccinini, Alberto Casati, Carlo Coniglio, Gregorio Tugnoli, Salomone Di Saverio
Nov 23, 2018
Background: The role of Emergency Thoracotomy (ET) in blunt trauma is still a matter of debate and in Europe only small studies have been published. We report our experience about ET both in penetrating and blunt trauma...
Ethical dimensions of translational developmental neuroscience research in autism.
Arianna Manzini, Emily JH Jones, Tony Charman, Mayada Elsabbagh, Mark H Johnson, Ilina Singh
Jul 01, 2021
BACKGROUND: Since the 1990s, increasing research has been devoted to the identification of biomarkers for autism to help attain more objective diagnosis; enable early prediction of prognosis; and guide individualized...
Laparoscopic adhesiolysis
Salomone Di Saverio, Arianna Birindelli, Richard Ten Broek, Justin R Davies, Matteo Mandrioli, Ville Sallinen
May 08, 2018
ASBO is a common cause of emergency surgery and the use of laparoscopy for the treatment of these patients is still under debate and conflicting results have been published, in particular regarding the high risk of iatrogenic...
Ethical dimensions of translational developmental neuroscience research in autism
Arianna Manzini, Emily J.H. Jones, Tony Charman, Mayada Elsabbagh, Mark H. Johnson, Ilina Singh
Aug 18, 2021
Special Issue Original Article Special Issue Original Articles autism Biomarkers Genetics Neurodevelopment Infant siblings ethics
Published by: Journal of Child Psychology and Psychiatry
Variant-specific vulnerability in metabolic connectivity and resting-state networks in behavioural variant of frontotemporal dementia.
Maura Malpetti, Giulia Carli, Arianna Sala, Chiara Cerami, Alessandra Marcone, Sandro Iannaccone, Giuseppe Magnani, Daniela Perani
Jul 10, 2020
Brain connectivity measures represent candidate biomarkers of neuronal dysfunction in neurodegenerative diseases. Previous findings suggest that the behavioural variant of frontotemporal dementia (bvFTD) and its variants (i.e....
Behavioural variant of frontotemporal dementia Brain metabolic connectivity Fluorine-18-flourodeoxiglucose positron emission tomography Aged Attention Brain Brain Mapping Cognition Connectome Female frontotemporal dementia Humans Male Memory Middle Aged Nerve Net Neuropsychological Tests Positron-Emission Tomography
Rare variants in axonogenesis genes connect three families with sound-color synesthesia.
Amanda K Tilot, Katerina S Kucera, Arianna Vino, Julian E Asher, Simon Baron-Cohen, Simon E Fisher
May 09, 2019
Synesthesia is a rare nonpathological phenomenon where stimulation of one sense automatically provokes a secondary perception in another. Hypothesized to result from differences in cortical wiring during development, synesthetes...
axonogenesis Perception Synaesthesia Synesthesia whole-exome sequencing Auditory Perception Axons Collagen Type IV Color Perception Female Gene Expression genetic variation Humans Integrin alpha2 Intercellular Signaling Peptides and Proteins Male Myosins Nerve Tissue Proteins Pedigree Perceptual Disorders RGS Proteins Receptors Cell Surface Receptors Immunologic Sodium-Hydrogen Exchangers Synesthesia
Identification of UBAP1 mutations in juvenile hereditary spastic paraplegia in the 100,000 Genomes Project
Thomas Bourinaris, Damian Smedley, Valentina Cipriani, Isabella Sheikh, Alkyoni Athanasiou-Fragkouli, Patrick Chinnery, Huw Morris, Raquel Real, Victoria Harrison, Evan Reid, Nicholas Wood, Jana Vandrovcova, Henry Houlden, Arianna Tucci
Dec 01, 2020
Abstract: Hereditary spastic paraplegia (HSP) is a group of heterogeneous inherited degenerative disorders characterized by lower limb spasticity. Fifty percent of HSP patients remain yet genetically undiagnosed. The 100,000...
Coherent phonons and the interplay between charge density wave and Mott phases in 1<i>T</i>-TaSe<sub>2</sub>
Charles Sayers, Hamoon Hedayat, Arianna Ceraso, Flavien Museur, Mattia Cattelan, Lewis Hart, Liam Farrar, Stefano Dal Conte, Giulio Cerullo, Claudia Dallera, Enrico Da Como, Ettore Carpene
Oct 08, 2020
1T-TaSe2 is host to coexisting strongly correlated phases including charge density waves (CDWs) and an unusual Mott transition at low temperature. Here, we investigate coherent phonon oscillations in...
Coherent phonons and the interplay between charge density wave and Mott phases in 1<i>T</i>-TaSe<sub>2</sub>
Charles Sayers, Hamoon Hedayat, Arianna Ceraso, Flavien Museur, Mattia Cattelan, Lewis Hart, Liam Farrar, Stefano Dal Conte, Giulio Cerullo, Claudia Dallera, Enrico Da Como, Ettore Carpene
Oct 08, 2020
1T-TaSe2 is host to coexisting strongly correlated phases including charge density waves (CDWs) and an unusual Mott transition at low temperature. Here, we investigate coherent phonon oscillations in...
F-actin dynamics regulates mammalian organ growth and cell fate maintenance.
Arianna Pocaterra, Giulia Santinon, Patrizia Romani, Irene Brian, Andrea Dimitracopoulos, Andrea Ghisleni, Alejandro Carnicer-Lombarte, Mattia Forcato, Paola Braghetta, Marco Montagner, Francesca Galuppini, Mariaceleste Aragona, Gianmaria Pennelli, Silvio Bicciato, Nils Gauthier, Kristian Franze, Sirio Dupont
Apr 05, 2019
Lifelong bilingualism and mechanisms of neuroprotection in Alzheimer dementia.
Arianna Sala, Maura Malpetti, Mohsen Farsad, Francesca Lubian, Giuseppe Magnani, Giulia Frasca Polara, Jean-Benoit Epiney, Jubin Abutalebi, Frédéric Assal, Valentina Garibotto, Daniela Perani
Nov 03, 2021
Lifelong bilingualism is associated with delayed dementia onset, suggesting a protective effect on the brain. Here, we aim to study the effects of lifelong bilingualism as a dichotomous and continuous phenomenon, on brain...
Identification of UBAP1 mutations in juvenile hereditary spastic paraplegia in the 100,000 Genomes Project.
Thomas Bourinaris, Damian Smedley, Valentina Cipriani, Isabella Sheikh, Alkyoni Athanasiou-Fragkouli, Patrick Chinnery, Huw Morris, Raquel Real, Victoria Harrison, Evan Reid, Nicholas Wood, Genomics England Research Consortium, Jana Vandrovcova, Henry Houlden, Arianna Tucci
Sep 15, 2021
Hereditary spastic paraplegia (HSP) is a group of heterogeneous inherited degenerative disorders characterized by lower limb spasticity. Fifty percent of HSP patients remain yet genetically undiagnosed. The 100,000 Genomes...
Poor CD4+ T Cell Immunogenicity Limits Humoral Immunity to P. falciparum Transmission-Blocking Candidate Pfs25 in Humans.
Marija Zaric, Arianna Marini, Carolyn M Nielsen, Gaurav Gupta, David Mekhaiel, Thao P Pham, Sean C Elias, Iona J Taylor, Hans de Graaf, Ruth O Payne, Yuanyuan Li, Sarah E Silk, Chris Williams, Adrian VS Hill, Carole A Long, Kazutoyo Miura, Sumi Biswas
Nov 25, 2021
Plasmodium falciparum transmission-blocking vaccines (TBVs) targeting the Pfs25 antigen have shown promise in mice but the same efficacy has never been achieved in humans. We have previously published pre-clinical data related...
CD4+ P. falciparum Pfs25 transmission blocking vaccine Adolescent Adult Animals Antibodies Protozoan B-Lymphocytes CD4-Positive T-Lymphocytes Cells Cultured Disease Models Animal Epitopes Female Humans Immunity Humoral Immunogenicity Vaccine Malaria Vaccines Malaria Falciparum Male Mice Mice Inbred BALB C Middle Aged Plasmodium falciparum Protozoan Proteins Recombinant Proteins Species Specificity Vaccination Young Adult
Reactivation of Myc transcription in the mouse heart unlocks its proliferative capacity
Megan J. Bywater, Deborah L. Burkhart, Jasmin Straube, Arianna Sabò, Vera Pendino, James E. Hudson, Gregory A. Quaife-Ryan, Enzo R. Porrello, James Rae, Robert G. Parton, Theresia R. Kress, Bruno Amati, Trevor D. Littlewood, Gerard I. Evan, Catherine H. Wilson
Apr 14, 2021
Abstract: It is unclear why some tissues are refractory to the mitogenic effects of the oncogene Myc. Here we show that Myc activation induces rapid transcriptional responses followed by proliferation in some, but not all...
The isolated carboxy-terminal domain of human mitochondrial leucyl-tRNA synthetase rescues the pathological phenotype of mitochondrial tRNA mutations in human cells.
Elena Perli, Carla Giordano, Annalinda Pisano, Arianna Montanari, Antonio F Campese, Aurelio Reyes, Daniele Ghezzi, Alessia Nasca, Helen A Tuppen, Maurizia Orlandi, Patrizio Di Micco, Elena Poser, Robert W Taylor, Gianni Colotti, Silvia Francisci, Veronica Morea, Laura Frontali, Massimo Zeviani, Giulia D'Amati
Nov 09, 2017
Mitochondrial (mt) diseases are multisystem disorders due to mutations in nuclear or mtDNA genes. Among the latter, more than 50% are located in transfer RNA (tRNA) genes and are responsible for a wide range of syndromes, for...
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