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The pharmaceutical solvent N-methyl-2-pyrollidone (NMP) attenuates inflammation through Krüppel-like factor 2 activation to reduce atherogenesis.
Marta Roche-Molina, Bryn Hardwick, Cristina Sanchez-Ramos, David Sanz-Rosa, Dirk Gewert, Francisco M Cruz, Andres Gonzalez-Guerra, Vicente Andres, Joaquin A Palma, Borja Ibanez, Grahame McKenzie, Juan A Bernal
Jul 28, 2021
N-methyl-2-pyrrolidone (NMP) is a versatile water-miscible polar aprotic solvent. It is used as a drug solubilizer and penetration enhancer in human and animal, yet its bioactivity properties remain elusive. Here, we report that...
Animals Anti-Inflammatory Agents Aorta Apoptosis Atherosclerosis Cell Adhesion Cell Line DNA Complementary Endothelial Cells Gene Expression Profiling Gene Library Human Umbilical Vein Endothelial Cells Humans Inflammation Kruppel-Like Transcription Factors Mice Mice Knockout ApoE Monocytes Pyrrolidinones RNA Small Interfering Solvents Tumor Necrosis Factor-alpha
Review of Bruno Latour, Down to Earth: Politics in the New Climatic Regime. Cambridge
Andrew Ahern
Jan 07, 2020
Bruno Latour’s 2017 publication, Down to Earth: Politics in the New Climatic Regime, is Latour’s analysis of the many political problems of today, including mass migration and worldwide inequality, all while the issue of climate...
Published by: Memorial University of Newfoundland
Review of Bruno Latour, Down to Earth: Politics in the New Climatic Regime. Cambridge
Andrew Ahern
Jan 07, 2020
Bruno Latour’s 2017 publication, Down to Earth: Politics in the New Climatic Regime, is Latour’s analysis of the many political problems of today, including mass migration and worldwide inequality, all while the issue of climate...
Published by: Memorial University of Newfoundland
The pharmaceutical solvent N-methyl-2-pyrollidone (NMP) attenuates inflammation through Krüppel-like factor 2 activation to reduce atherogenesis
Marta Roche-Molina, Bryn Hardwick, Cristina Sanchez-Ramos, David Sanz-Rosa, Dirk Gewert, Francisco M. Cruz, Andres Gonzalez-Guerra, Vicente Andres, Joaquin A. Palma, Borja Ibanez, Grahame McKenzie, Juan A. Bernal
Jul 15, 2020
Abstract: N-methyl-2-pyrrolidone (NMP) is a versatile water-miscible polar aprotic solvent. It is used as a drug solubilizer and penetration enhancer in human and animal, yet its bioactivity properties remain elusive. Here, we...
Local Limit Theorems for the Random Conductance Model and Applications to the Ginzburg–Landau $$\nabla \phi $$ Interface Model
Abstract We study a continuous-time random walk on$${\mathbb {Z}}^d$$
Review of Gianni Vattimo, A Farewell to Truth, trans. William McCuaig. New York
Daniel Mariano Leiro
Mar 23, 2016
Could a book such as A Farewell to Truth by Gianni Vattimo have been better received? It doesn’t seem so. Those who think that saying goodbye to the truth might be a much too risky business are still the majority. However...
Published by: Memorial University of Newfoundland
A Review of Spectrum Sensing Techniques Based on Machine Learning
This article presents a survey of current spectrum sensing (SS) research involving the application of image processing and deep learning techniques. This document includes approaches to narrowband, wideband, and cooperative SS....
Global Information Technology Computer Science and Information Technology Global Information Technology Physical Sciences and Engineering Business and Management
Published by: IGI Global Scientific Publishing
Local Limit Theorems for the Random Conductance Model and Applications to the Ginzburg–Landau ∇ ϕ Interface Model
Abstract: We study a continuous-time random walk on Zd in an environment of random conductances taking values in (0, ∞). For a static environment, we extend the quenched local limit theorem to the case of a general speed...
Berry–Esseen theorem and quantitative homogenization for the random conductance model with degenerate conductances
We study the random conductance model on the lattice $Z^d$, i.e. we consider a linear, finite-difference, divergence-form operator with random coefficients and the associated random walk under random conductances. We allow the...
Review of Gianni Vattimo, A Farewell to Truth, trans. William McCuaig. New York
Daniel Mariano Leiro
Mar 23, 2016
Could a book such as A Farewell to Truth by Gianni Vattimo have been better received? It doesn’t seem so. Those who think that saying goodbye to the truth might be a much too risky business are still the majority. However...
Published by: Memorial University of Newfoundland
Andrea Mantegna's Wedding Chamber
The Wedding Chamber fresco, also known as Camera Picta, or La Camera Degli Sposi, painted by Andrea Mantegna at the dawn of the Renaissance, epitomizes the most outstanding expression of personal creativity and innovation from...
Published by: IGI Global Scientific Publishing
Variational Autoencoders for Cancer Data Integration
Nikola Simidjievski, Cristian Bodnar, Ifrah Tariq, Paul Scherer, Helena Andres Terre, Zohreh Shams, Mateja Jamnik, Pietro Liò
Jan 17, 2020
International initiatives such as the Molecular Taxonomy of Breast Cancer International Consortium are collecting multiple data sets at different genome-scales with the aim to identify novel cancer bio-markers and predict...
Genetic Variation in Neurotransmitter Receptors Generates Behavioral Diversity
Andres Bendesky
Jan 01, 0001
Variation in behavior among individuals is both remarkable and of great significance to society. People differ in locomotor skills, in sleep patterns, in their willingness to take risks, and in how they relate to other people....
Published by: Rockefeller University
Online information on face masks
OBJECTIVE: Countries have major differences in the acceptance of face mask use for the prevention of COVID-19. This work aims at studying the information online in different countries in terms of information quality and content....
A Framework for Automated Scraping of Structured Data Records From the Deep Web Using Semantic Labeling
The intent of this research is to come up with an automated web scraping system which is capable of extracting structured data records embedded in semi-structured web pages. Most of the automated extraction techniques in the...
Published by: IGI Global Scientific Publishing
MicroExonator enables systematic discovery and quantification of microexons across mouse embryonic development
Guillermo E. Parada, Roberto Munita, Ilias Georgakopoulos-Soares, Hugo J. R. Fernandes, Veronika R. Kedlian, Emmanouil Metzakopian, Maria Estela Andres, Eric A. Miska, Martin Hemberg
Jan 22, 2021
Abstract: Background: Microexons, exons that are ≤ 30 nucleotides, are a highly conserved and dynamically regulated set of cassette exons. They have key roles in nervous system development and function, as evidenced by recent...
The Role of Microglia in the Effects of Steroid Hormones on Brain Inflammation
Andres C. Gottfried-Blackmore
Jan 01, 0001
The conditions defining whether microglial activation is detrimental or beneficial to neuronal survival are still poorly understood. Better understanding of the factors regulating microglia activation may lead to improved...
Neurodegenerative Diseases Microglia microglia activation Steroid hormones Corticosterone E2 Life Sciences
Published by: Rockefeller University
PomBase 2018
Antonia Lock, Kim Rutherford, Midori A Harris, Jacqueline Hayles, Stephen G Oliver, Jürg Bähler, Valerie Wood
Nov 21, 2018
PomBase (www.pombase.org), the model organism database for the fission yeast Schizosaccharomyces pombe, has undergone a complete redevelopment, resulting in a more fully integrated, better-performing service. The new...
Health-related quality of life in paediatric patients with Type 1 diabetes mellitus using insulin infusion systems. A systematic review and meta-analysis.
BACKGROUND: In 2017, more than 1.1 million children were living with type 1 diabetes mellitus (T1DM) globally. The goal in paediatric diabetes therapy is reaching optimal glycaemic control as early as possible in order to avoid...
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