Search
Results: 31
A Common Glaucoma-risk Variant of SIX6 Alters Retinal Nerve Fiber Layer and Optic Disc Measures in a European Population
Deriving the exact nonadiabatic quantum propagator in the mapping variable representation
We derive an exact quantum propagator for nonadiabatic dynamics in multi-state systems using the mapping variable representation, where classical-like Cartesian variables are used to represent both continuous nuclear degrees of...
Nonadiabatic semiclassical dynamics in the mixed quantum-classical initial value representation.
We extend the Mixed Quantum-Classical Initial Value Representation (MQC-IVR), a semiclassical method for computing real-time correlation functions, to electronically nonadiabatic systems using the Meyer-Miller-Stock-Thoss (MMST)...
A mapping variable ring polymer molecular dynamics study of condensed phase proton-coupled electron transfer.
We investigate the mechanisms of condensed phase proton-coupled electron transfer (PCET) using Mapping-Variable Ring Polymer Molecular Dynamics (MV-RPMD), a recently developed method that employs an ensemble of classical...
Template-Based Question Answering System Over the Semantic Web
A question answering system is the most promising way of retrieving data from the available knowledge base to the end-users to get the appropriate result for their questions. Many question answering systems convert the questions...
Published by: IGI Global Scientific Publishing
Elongational stalling activates mitoribosome-associated quality control.
Nirupa Desai, Hanting Yang, Viswanathan Chandrasekaran, Razina Kazi, Michal Minczuk, V Ramakrishnan
Dec 01, 2020
The human mitochondrial ribosome (mitoribosome) and associated proteins regulate the synthesis of 13 essential subunits of the oxidative phosphorylation complexes. We report the discovery of a mitoribosome-associated quality...
Cryoelectron Microscopy Electron Transport Complex IV Escherichia coli Exoribonucleases HEK293 Cells Humans Mitochondrial Proteins Mitochondrial Ribosomes Nuclear Proteins Peptide Termination Factors Protein Domains RNA Transfer RNA-Binding Proteins Ribosomal Proteins Transcription Elongation Genetic Transcriptional Elongation Factors
Visualizing formation of the active site in the mitochondrial ribosome.
Viswanathan Chandrasekaran, Nirupa Desai, Nicholas O Burton, Hanting Yang, Jon Price, Eric A Miska, V Ramakrishnan
Nov 05, 2021
human Biochemistry C. elegans structural biology chemical biology cryo-EM RNA modifications peptidyl transferase center molecular biophysics mitochondrial ribosome
Published by: eLife
Prevalence of occult nodal metastases in squamous cell carcinoma of the temporal bone
Daniele Borsetto, Ananth Vijendren, Giovanni Franchin, Neil Donnelly, Patrick Axon, Matthew Smith, Liam Masterson, Manohar Bance, Athanasios Saratziotis, Jerry Polesel, Paolo Boscolo-Rizzo, James Tysome
Nov 15, 2022
PURPOSE: Primary: To determine the rate of occult cervical metastases in primary temporal bone squamous cell carcinomas (TBSSC). Secondary: to perform a subgroup meta-analysis of the risk of occult metastases based on the...
A systematic review on prevention and management of wound infections from cochlear implantation.
Ananth Vijendren, Daniele Borsetto, Eleanor J Barker, Joseph G Manjaly, James R Tysome, Patrick R Axon, Neil P Donnelly, Manohar L Bance
Apr 14, 2020
OBJECTIVE OF REVIEW: Surgical site infections are a recognised complication of cochlear implant (CI) surgery with significant morbidity. Our aim was to search for the optimum prevention and management strategy to deal with this...
Lifetime risk of diabetes in metropolitan cities in India.
Shammi Luhar, Dimple Kondal, Rebecca Jones, Ranjit M Anjana, Shivani A Patel, Sanjay Kinra, Lynda Clarke, Mohammed K Ali, Dorairaj Prabhakaran, M Masood Kadir, Nikhil Tandon, Viswanathan Mohan, KM Venkat Narayan
Feb 05, 2021
AIMS/HYPOTHESIS: We aimed to estimate the lifetime risk of diabetes and diabetes-free life expectancy in metropolitan cities in India among the population aged 20 years or more, and their variation by sex, age and BMI. METHODS...
Body Mass Index Diabetes Diabetes-free life expectancy india lifetime risk Metropolitan cities urban Adult Age Distribution Diabetes mellitus Disease-Free Survival Female Humans Incidence india Life Expectancy Male Markov Chains Middle Aged Models Theoretical obesity prevalence Risk Assessment Risk Factors Sex Distribution Time Factors Urban Health Young Adult
Prevalence of occult nodal metastases in squamous cell carcinoma of the temporal bone
Daniele Borsetto, Ananth Vijendren, Giovanni Franchin, Neil Donnelly, Patrick Axon, Matthew Smith, Liam Masterson, Manohar Bance, Athanasios Saratziotis, Jerry Polesel, Paolo Boscolo-Rizzo, James Tysome
Jan 04, 2023
PURPOSE: Primary: To determine the rate of occult cervical metastases in primary temporal bone squamous cell carcinomas (TBSSC). Secondary: to perform a subgroup meta-analysis of the risk of occult metastases based on the...
Transcriptional profiling of MnSOD-mediated lifespan extension in Drosophila reveals a species-general network of aging and metabolic genes.
A genome-wide screen identifies YAP/WBP2 interplay conferring growth advantage on human epidermal stem cells.
Gernot Walko, Samuel Woodhouse, Angela Oliveira Pisco, Emanuel Rognoni, Kifayathullah Liakath-Ali, Beate M Lichtenberger, Ajay Mishra, Stephanie B Telerman, Priyalakshmi Viswanathan, Meike Logtenberg, Lisa M Renz, Giacomo Donati, Sven R Quist, Fiona M Watt
Feb 07, 2019
Individual human epidermal cells differ in their self-renewal ability. To uncover the molecular basis for this heterogeneity, we performed genome-wide pooled RNA interference screens and identified genes conferring a clonal...
Impacts of acoustic and gravity waves on the ionosphere
Kate Zawdie, Anna Belehaki, Meghan Burleigh, Min Yang Chou, Manbharat S. Dhadly, Katelynn Greer, Alexa J. Halford, Dustin Hickey, Pavel Inchin, Stephen R. Kaeppler, Jeff Klenzing, Viswanathan Lakshmi Narayanan, Fabrizio Sassi, Mani Sivakandan, Jonathon M. Smith, Nikolay Zabotin, Matthew D. Zettergren, Shun Rong Zhang
Nov 15, 2022
The impact of regional-scale neutral atmospheric waves has been demonstrated to have profound effects on the ionosphere, but the circumstances under which they generate ionospheric disturbances and seed plasma instabilities...
Aβ efflux impairment and inflammation linked to cerebrovascular accumulation of amyloid-forming amylin secreted from pancreas.
Nirmal Verma, Gopal Viswanathan Velmurugan, Edric Winford, Han Coburn, Deepak Kotiya, Noah Leibold, Laura Radulescu, Sanda Despa, Kuey C Chen, Linda J Van Eldik, Peter T Nelson, Donna M Wilcock, Gregory A Jicha, Ann M Stowe, Larry B Goldstein, David K Powel, Jeffrey H Walton, Manuel F Navedo, Matthew A Nystoriak, Andrew J Murray, Geert Jan Biessels, Claire Troakes, Henrik Zetterberg, John Hardy, Tammaryn Lashley, Florin Despa
Jan 04, 2023
Impacts of acoustic and gravity waves on the ionosphere
Kate Zawdie, Anna Belehaki, Meghan Burleigh, Min Yang Chou, Manbharat S. Dhadly, Katelynn Greer, Alexa J. Halford, Dustin Hickey, Pavel Inchin, Stephen R. Kaeppler, Jeff Klenzing, Viswanathan Lakshmi Narayanan, Fabrizio Sassi, Mani Sivakandan, Jonathon M. Smith, Nikolay Zabotin, Matthew D. Zettergren, Shun Rong Zhang
Nov 15, 2022
The impact of regional-scale neutral atmospheric waves has been demonstrated to have profound effects on the ionosphere, but the circumstances under which they generate ionospheric disturbances and seed plasma instabilities...
Polymorphism in a lincRNA Associates with a Doubled Risk of Pneumococcal Bacteremia in Kenyan Children.
Kenyan Bacteraemia Study Group, Wellcome Trust Case Control Consortium 2 (WTCCC2), Anna Rautanen, Matti Pirinen, Tara C Mills, Kirk A Rockett, Amy Strange, Anne W Ndungu, Vivek Naranbhai, James J Gilchrist, Céline Bellenguez, Colin Freeman, Gavin Band, Suzannah J Bumpstead, Sarah Edkins, Eleni Giannoulatou, Emma Gray, Serge Dronov, Sarah E Hunt, Cordelia Langford, Richard D Pearson, Zhan Su, Damjan Vukcevic, Alex W Macharia, Sophie Uyoga, Carolyne Ndila, Neema Mturi, Patricia Njuguna, Shebe Mohammed, James A Berkley, Isaiah Mwangi, Salim Mwarumba, Barnes S Kitsao, Brett S Lowe, Susan C Morpeth, Iqbal Khandwalla, Kilifi Bacteraemia Surveillance Group, Jenefer M Blackwell, Elvira Bramon, Matthew A Brown, Juan P Casas, Aiden Corvin, Audrey Duncanson, Janusz Jankowski, Hugh S Markus, Christopher G Mathew, Colin NA Palmer, Robert Plomin, Stephen J Sawcer, Richard C Trembath, Ananth C Viswanathan, Nicholas W Wood, Panos Deloukas, Leena Peltonen, Thomas N Williams, J Anthony G Scott, Stephen J Chapman, Peter Donnelly, Adrian VS Hill, Chris CA Spencer
Jun 10, 2016
Aβ efflux impairment and inflammation linked to cerebrovascular accumulation of amyloid-forming amylin secreted from pancreas.
Nirmal Verma, Gopal Viswanathan Velmurugan, Edric Winford, Han Coburn, Deepak Kotiya, Noah Leibold, Laura Radulescu, Sanda Despa, Kuey C Chen, Linda J Van Eldik, Peter T Nelson, Donna M Wilcock, Gregory A Jicha, Ann M Stowe, Larry B Goldstein, David K Powel, Jeffrey H Walton, Manuel F Navedo, Matthew A Nystoriak, Andrew J Murray, Geert Jan Biessels, Claire Troakes, Henrik Zetterberg, John Hardy, Tammaryn Lashley, Florin Despa
Feb 09, 2023
Genetic loci for retinal arteriolar microcirculation.
Xueling Sim, Richard A Jensen, M Kamran Ikram, Mary Frances Cotch, Xiaohui Li, Stuart MacGregor, Jing Xie, Albert Vernon Smith, Eric Boerwinkle, Paul Mitchell, Ronald Klein, Barbara EK Klein, Nicole L Glazer, Thomas Lumley, Barbara McKnight, Bruce M Psaty, Paulus TVM de Jong, Albert Hofman, Fernando Rivadeneira, Andre G Uitterlinden, Cornelia M van Duijn, Thor Aspelund, Gudny Eiriksdottir, Tamara B Harris, Fridbert Jonasson, Lenore J Launer, Wellcome Trust Case Control Consortium 2, John Attia, Paul N Baird, Stephen Harrap, Elizabeth G Holliday, Michael Inouye, Elena Rochtchina, Rodney J Scott, Ananth Viswanathan, Global BPGen Consortium, Guo Li, Nicholas L Smith, Kerri L Wiggins, Jane Z Kuo, Kent D Taylor, Alex W Hewitt, Nicholas G Martin, Grant W Montgomery, Cong Sun, Terri L Young, David A Mackey, Natalie R Van Zuydam, Alex SF Doney, Colin NA Palmer, Andrew D Morris, Jerome I Rotter, E Shyong Tai, Vilmundur Gudnason, Johannes R Vingerling, David S Siscovick, Jie Jin Wang, Tien Y Wong
Jan 23, 2018
Narrow arterioles in the retina have been shown to predict hypertension as well as other vascular diseases, likely through an increase in the peripheral resistance of the microcirculatory flow. In this study, we performed a...
Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
Richa Saxena, Danish Saleheen, Latonya F Been, Martha L Garavito, Timothy Braun, Andrew Bjonnes, Robin Young, Weang Kee Ho, Asif Rasheed, Philippe Frossard, Xueling Sim, Neelam Hassanali, Venkatesan Radha, Manickam Chidambaram, Samuel Liju, Simon D Rees, Daniel Peng-Keat Ng, Tien-Yin Wong, Toshimasa Yamauchi, Kazuo Hara, Yasushi Tanaka, Hiroshi Hirose, Mark I McCarthy, Andrew P Morris, DIAGRAM, MuTHER, AGEN, Abdul Basit, Anthony H Barnett, Prasad Katulanda, David Matthews, Viswanathan Mohan, Gurpreet S Wander, Jai Rup Singh, Narinder K Mehra, Sarju Ralhan, M Ilyas Kamboh, John J Mulvihill, Hiroshi Maegawa, Kazuyuki Tobe, Shiro Maeda, Yoon S Cho, E Shyong Tai, M Ann Kelly, John C Chambers, Jaspal S Kooner, Takashi Kadowaki, Panos Deloukas, Daniel J Rader, John Danesh, Dharambir K Sanghera
Jun 11, 2018
We performed a genome-wide association study (GWAS) and a multistage meta-analysis of type 2 diabetes (T2D) in Punjabi Sikhs from India. Our discovery GWAS in 1,616 individuals (842 case subjects) was followed by in silico...
Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21.
Rubina Tabassum, Ganesh Chauhan, Om Prakash Dwivedi, Anubha Mahajan, Alok Jaiswal, Ismeet Kaur, Khushdeep Bandesh, Tejbir Singh, Benan John Mathai, Yogesh Pandey, Manickam Chidambaram, Amitabh Sharma, Sreenivas Chavali, Shantanu Sengupta, Lakshmi Ramakrishnan, Pradeep Venkatesh, Sanjay K Aggarwal, Saurabh Ghosh, Dorairaj Prabhakaran, Reddy K Srinath, Madhukar Saxena, Monisha Banerjee, Sandeep Mathur, Anil Bhansali, Viral N Shah, Sri Venkata Madhu, Raman K Marwaha, Analabha Basu, Vinod Scaria, Mark I McCarthy, DIAGRAM, INDICO, Radha Venkatesan, Viswanathan Mohan, Nikhil Tandon, Dwaipayan Bharadwaj
Feb 22, 2018
Indians undergoing socioeconomic and lifestyle transitions will be maximally affected by epidemic of type 2 diabetes (T2D). We conducted a two-stage genome-wide association study of T2D in 12,535 Indians, a less explored but...
|
|< |
< |
1 |