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Results: 8
Functional interplay of Epstein-Barr virus oncoproteins in a mouse model of B cell lymphomagenesis.
Thomas Sommermann, Tomoharu Yasuda, Jonathan Ronen, Tristan Wirtz, Timm Weber, Ulrike Sack, Rebecca Caeser, Jingwei Zhang, Xun Li, Van Trung Chu, Anna Jauch, Kristian Unger, Daniel J Hodson, Altuna Akalin, Klaus Rajewsky
Jun 15, 2020
Epstein-Barr virus (EBV) is a B cell transforming virus that causes B cell malignancies under conditions of immune suppression. EBV orchestrates B cell transformation through its latent membrane proteins (LMPs) and Epstein-Barr...
B cell lymphomagenesis EBNA Epstein-Barr virus LMP1 plasma cell differentiation Animals Cell Differentiation Cell Line Tumor Cell Transformation Viral DNA-Binding Proteins Disease Models Animal Epstein-Barr Virus Infections Epstein-Barr Virus Nuclear Antigens FIBROBLASTS Herpesvirus 4 Human Humans Lymphoma B-Cell Mice Mice Knockout Plasma Cells Primary Cell Culture Trans-Activators Viral Matrix Proteins Viral Proteins
Determinants of Cryptocurrency Exchange Adoption
Cryptocurrencies have become a global phenomenon, and the number of registered users of cryptocurrency exchange platforms has grown worldwide. However, only a small number of the registered users are active users that engage in...
Published by: IGI Global Scientific Publishing
Cell-type specialization is encoded by specific chromatin topologies.
Warren Winick-Ng, Alexander Kukalev, Izabela Harabula, Luna Zea-Redondo, Dominik Szabó, Mandy Meijer, Leonid Serebreni, Yingnan Zhang, Simona Bianco, Andrea M Chiariello, Ibai Irastorza-Azcarate, Christoph J Thieme, Thomas M Sparks, Sílvia Carvalho, Luca Fiorillo, Francesco Musella, Ehsan Irani, Elena Torlai Triglia, Aleksandra A Kolodziejczyk, Andreas Abentung, Galina Apostolova, Eleanor J Paul, Vedran Franke, Rieke Kempfer, Altuna Akalin, Sarah A Teichmann, Georg Dechant, Mark A Ungless, Mario Nicodemi, Lonnie Welch, Gonçalo Castelo-Branco, Ana Pombo
Jan 07, 2022
The three-dimensional (3D) structure of chromatin is intrinsically associated with gene regulation and cell function1-3. Methods based on chromatin conformation capture have mapped chromatin structures in neuronal systems such...
Cell-type specialization is encoded by specific chromatin topologies.
Warren Winick-Ng, Alexander Kukalev, Izabela Harabula, Luna Zea-Redondo, Dominik Szabó, Mandy Meijer, Leonid Serebreni, Yingnan Zhang, Simona Bianco, Andrea M Chiariello, Ibai Irastorza-Azcarate, Christoph J Thieme, Thomas M Sparks, Sílvia Carvalho, Luca Fiorillo, Francesco Musella, Ehsan Irani, Elena Torlai Triglia, Aleksandra A Kolodziejczyk, Andreas Abentung, Galina Apostolova, Eleanor J Paul, Vedran Franke, Rieke Kempfer, Altuna Akalin, Sarah Teichmann, Georg Dechant, Mark A Ungless, Mario Nicodemi, Lonnie Welch, Gonçalo Castelo-Branco, Ana Pombo
Nov 24, 2021
The three-dimensional (3D) structure of chromatin is intrinsically associated with gene regulation and cell function1-3. Methods based on chromatin conformation capture have mapped chromatin structures in neuronal systems such...
Big Data Analytics and Culture
Kamel Rouibah, Abdou Illia, Assion Lawson-Body, Laurence Lawson-Body, Gurkan Akalin, Eric Tamandja
Jan 01, 2024
The existing big data analytics measures were developed without considering the cultural dimensions of developing countries. This research aims to develop and validate measures for big data Vs and cultural big data analytics and...
Published by: IGI Global Scientific Publishing
Clinical and biomarker changes of Alzheimer's disease in adults with Down syndrome
Juan Fortea, Eduard Vilaplana, Maria Carmona-Iragui, Bessy Benejam, Laura Videla, Isabel Barroeta, Susana Fernández, Miren Altuna, Jordi Pegueroles, Víctor Montal, Silvia Valldeneu, Sandra Giménez, Sofía González-Ortiz, Laia Muñoz, Teresa Estellés, Ignacio Illán-Gala, Olivia Belbin, Valle Camacho, Liam Reese Wilson, Tiina Annus, Ricardo S Osorio, Sebastián Videla, Sylvain Lehmann, Anthony J Holland, Daniel Alcolea, Jordi Clarimón, Shahid H Zaman, Rafael Blesa, Alberto Lleó
Jul 06, 2020
BACKGROUND: Alzheimer's disease and its complications are the leading cause of death in adults with Down syndrome. Studies have assessed Alzheimer's disease in individuals with Down syndrome, but the natural history of biomarker...
Adult Alzheimer Disease Amyloid beta-Peptides Amyloidosis Apolipoproteins E Biomarkers Case-Control Studies Cognitive Dysfunction Cross-Sectional Studies Down Syndrome Fluorodeoxyglucose F18 Humans Magnetic Resonance Imaging Middle Aged Neurofilament Proteins Positron-Emission Tomography prevalence Spain United Kingdom tau Proteins