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Secret Remedies and the Medical Needs of the French State
Justin Rivest
Sep 29, 2018
This article explores the relation between proprietary drugs and state interests in early modern France by following the career of the medical entrepreneur Adrien Helvétius (1662–1727). Helvétius began as a private practitioner...
GRIM REAPER peptide binds to receptor kinase PRK5 to trigger cell death in Arabidopsis.
Michael Wrzaczek, Julia P Vainonen, Simon Stael, Liana Tsiatsiani, Hanna Help-Rinta-Rahko, Adrien Gauthier, David Kaufholdt, Benjamin Bollhöner, Airi Lamminmäki, An Staes, Kris Gevaert, Hannele Tuominen, Frank Van Breusegem, Ykä Helariutta, Jaakko Kangasjärvi
May 08, 2019
Recognition of extracellular peptides by plasma membrane-localized receptor proteins is commonly used in signal transduction. In plants, very little is known about how extracellular peptides are processed and activated in order...
Unravelling Chemical Composition of Agave Spines
Dalia C Morán-Velázquez, Juan L Monribot-Villanueva, Matthieu Bourdon, John Z Tang, Itzel López-Rosas, Luis F Maceda-López, José L Villalpando-Aguilar, Lorena Rodríguez-López, Adrien Gauthier, Laura Trejo, Parastoo Azadi, Francisco Vilaplana, José A Guerrero-Analco, Fulgencio Alatorre-Cobos
Nov 26, 2020
Spines are key plant modifications developed to deal against herbivores; however, its physical structure and chemical composition have been little explored in plant species. Here, we took advantage of high-throughput...
Tumour heterogeneity promotes collective invasion and cancer metastatic dissemination.
Heterogeneity within tumour cell populations is commonly observed in most cancers. However, its impact on metastatic dissemination, one of the primary determinants of the disease prognosis, remains poorly understood. Working...
Phonons as a platform for non-Abelian braiding and its manifestation in layered silicates.
Topological phases of matter have revolutionised the fundamental understanding of band theory and hold great promise for next-generation technologies such as low-power electronics or quantum computers. Single-gap topologies have...
On growth and force
The EMBO/EMBL Symposium 'Mechanical Forces in Development' was held in Heidelberg, Germany, on 3-6 July 2019. This interdisciplinary symposium brought together an impressive and diverse line-up of speakers seeking to address the...
Mechanical forces Mechanobiology Mechanosensation Mechanotransduction Morphogenesis Animals biophysics developmental biology Gene Expression Regulation Developmental Germany Homeostasis Humans Interdisciplinary Research Mechanotransduction Cellular Models Biological Morphogenesis Plant Physiological Phenomena Stress Mechanical
A transitional snake from the Late Cretaceous period of North America
Snakes are the most diverse group of lizards, but their origins and early evolution remain poorly understood owing to a lack of transitional forms. Several major issues remain outstanding, such as whether snakes originated in a...
Phonons as a platform for non-Abelian braiding and its manifestation in layered silicates.
Topological phases of matter have revolutionised the fundamental understanding of band theory and hold great promise for next-generation technologies such as low-power electronics or quantum computers. Single-gap topologies have...
Growth of gas-filled penny-shaped cracks in decompressed hydrogels.
We report that the decompression of soft brittle materials can lead to the growth of internal gas-filled cracks. These cracks are oblate spheroids ('penny shape'), whose major radius grows linearly in time, irreversibly...
Theory of mechanochemical patterning in biphasic biological tissues.
The formation of self-organized patterns is key to the morphogenesis of multicellular organisms, although a comprehensive theory of biological pattern formation is still lacking. Here, we propose a minimal model combining tissue...
A magnetically actuated, optically sensed tensile testing method for mechanical characterization of soft biological tissues.
Mechanical properties of soft biological tissues play a critical role in physiology and disease, affecting cell behavior and fate decisions and contributing to tissue development, maintenance, and repair. Limitations of existing...
The history of climate and society
Abstract
Recent decades have seen the rapid expansion of scholarship that identifies societal responses to past climatic fluctuations. This fast-changing scholarship, which was...
Dagomar Degroot, Kevin J Anchukaitis, Jessica E Tierney, Felix Riede, Andrea Manica, Emma Moesswilde, Nicolas Gauthier
Sep 21, 2022
A parametric model to identify hydrodynamic bearing wear at a single rotating speed
For dynamic systems, fault detection and diagnosis involve the observation of vibration signals. Faults associated with hydrodynamic bearings are one of the most common causes of forced shutdowns in rotating machinery. If it is...
A parametric model to identify hydrodynamic bearing wear at a single rotating speed
For dynamic systems, fault detection and diagnosis involve the observation of vibration signals. Faults associated with hydrodynamic bearings are one of the most common causes of forced shutdowns in rotating machinery. If it is...
Biogeography of worm lizards (Amphisbaenia) driven by end-Cretaceous mass extinction
Worm lizards (Amphisbaenia) are burrowing squamates that live as subterranean predators. Their underground existence should limit dispersal, yet they are widespread throughout the Americas, Europe and Africa. This pattern was...
A transitional snake from the Late Cretaceous period of North America
Snakes are the most diverse group of lizards, but their origins and early evolution remain poorly understood owing to a lack of transitional forms. Several major issues remain outstanding, such as whether snakes originated in a...
Biogeography of worm lizards (Amphisbaenia) driven by end-Cretaceous mass extinction
Worm lizards (Amphisbaenia) are burrowing squamates that live as subterranean predators. Their underground existence should limit dispersal, yet they are widespread throughout the Americas, Europe and Africa. This pattern was...
Multidirectional chromosome painting substantiates the occurrence of extensive genomic reshuffling within Accipitriformes.
Wenhui Nie, Patricia CM O'Brien, Beiyuan Fu, Jinghuan Wang, Weiting Su, Kai He, Bertrand Bed'hom, Vitaly Volobouev, Malcolm A Ferguson-Smith, Gauthier Dobigny, Fengtang Yang
Sep 29, 2016
BACKGROUND: Previous cross-species painting studies with probes from chicken (Gallus gallus) chromosomes 1-10 and a paint pool of nineteen microchromosomes have revealed that the drastic karyotypic reorganization in Accipitridae...
Sedation Modulates Frontotemporal Predictive Coding Circuits and the Double Surprise Acceleration Effect.
The history of climate and society
Abstract Recent decades have seen the rapid expansion of scholarship that identifies societal responses to past climatic fluctuations. This fast-changing scholarship, which was recently...
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