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The Stories We Tell Influence the Support We Receive
Nadia Adelina, Christian S Chan, Keisuke Takano, Placida Hoi Man Yu, Patrina Hei Tung Wong, Tom J Barry
Nov 07, 2023
Although social support facilitates coping and recovering from stressful life events, people do not always get the support that they need. Prior research suggests that the way one talks about stressful events to others may...
Stacking-dependent superstructures at stepped armchair interfaces of bilayer/trilayer graphene
We present the first study of quantum interference patterns at a bilayer-trilayer armchair interface, for different stacking sequences. Visualization using scanning tunneling microscopy and theoretical calculations provide...
Challenges and Opportunities for the Large-Scale Chemoenzymatic Glycoengineering of Therapeutic N-Glycosylated Monoclonal Antibodies
Variability in the glycosylation profile of therapeutic monoclonal antibodies (mAbs), due to recombinant production technologies, leads to inconsistencies in effector functions and pharmacokinetic properties, both...
The Stories We Tell Influence the Support We Receive
Nadia Adelina, Christian S Chan, Keisuke Takano, Placida Hoi Man Yu, Patrina Hei Tung Wong, Tom J Barry
Nov 07, 2023
Although social support facilitates coping and recovering from stressful life events, people do not always get the support that they need. Prior research suggests that the way one talks about stressful events to others may...
Raman spectra of monolayer, few-layer, and bulk ReSe<sub>2</sub>
Rhenium diselenide (ReSe2) is a layered indirect gap semiconductor for which micromechanical cleavage can produce monolayers consisting of a plane of rhenium atoms with selenium atoms above and below....
Repair and stabilization in confined nanoscale systems
Repair is ubiquitous in biological systems, but rare in the inorganic world. We show that inorganic nanoscale systems can however possess remarkable repair and reconfiguring capabilities when subjected to extreme confinement....
Ca2+ Release by IP3 Receptors Is Required to Orient the Mitotic Spindle.
The mitotic spindle distributes chromosomes evenly to daughter cells during mitosis. The orientation of the spindle, guided by internal and external cues, determines the axis of cell division and thereby contributes to tissue...
Self-consistent charge and dipole density functional tight binding method and application to carbon-based systems
The density functional tight binding (DFTB) method is a fast, semi-empirical, total energy electronic structure method based upon and parameterized to density functional theory (DFT). The standard self-consistent charge (SCC)...
Operator-norm convergence estimates for elliptic homogenization problems on periodic singular structures
For an arbitrary periodic Borel measure μ we prove order O(ε) operator-norm resolvent estimates for the solutions to scalar elliptic problems in L 2(ℝ d, dμ ε) with ε-periodic coefficients, ε...
Repair and stabilization in confined nanoscale systems
Repair is ubiquitous in biological systems, but rare in the inorganic world. We show that inorganic nanoscale systems can however possess remarkable repair and reconfiguring capabilities when subjected to extreme confinement....
Stacking-dependent superstructures at stepped armchair interfaces of bilayer/trilayer graphene
We present the first study of quantum interference patterns at a bilayer-trilayer armchair interface, for different stacking sequences. Visualization using scanning tunneling microscopy and theoretical calculations provide...
Self-consistent charge and dipole density functional tight binding method and application to carbon-based systems
The density functional tight binding (DFTB) method is a fast, semi-empirical, total energy electronic structure method based upon and parameterized to density functional theory (DFT). The standard self-consistent charge (SCC)...
A Modular Bio-Platform Based on a Versatile Supramolecular Multi-Enzyme Complex Directly Attached to Graphene
Abeer Alshammari, Mareike G. Posner, Abhishek Upadhyay, Frank Marken, Stefan Bagby, Adelina Ilie
Aug 17, 2016
Developing generic strategies for building adaptable or multi-functional bio-platforms is challenging, in particular because protein immobilization onto surfaces often causes loss of protein function and multi-functionality...
WS2 Nanotubes, 2D Nanomeshes, and 2D In-Plane Films Through One Single Chemical Vapor Deposition route
Zichen Liu, Alexander Murphy, Christian Kuppe, David Hooper, Ventsislav Valev, Adelina Ilie
Apr 23, 2019
We demonstrate a versatile, catalyst free chemical vapor deposition process on insulating substrates capable of producing in one single stream one-dimensional (1D) WO3- x suboxides leading to a wide range of...
WS2 Nanotubes, 2D Nanomeshes, and 2D In-Plane Films Through One Single Chemical Vapor Deposition route
Zichen Liu, Alexander Murphy, Christian Kuppe, David Hooper, Ventsislav Valev, Adelina Ilie
Apr 23, 2019
We demonstrate a versatile, catalyst free chemical vapor deposition process on insulating substrates capable of producing in one single stream one-dimensional (1D) WO3- x suboxides leading to a wide range of...
Operator-norm convergence estimates for elliptic homogenization problems on periodic singular structures
For an arbitrary periodic Borel measure μ we prove order O(ε) operator-norm resolvent estimates for the solutions to scalar elliptic problems in L 2(ℝ d, dμ ε) with ε-periodic coefficients, ε...
Raman spectra of monolayer, few-layer, and bulk ReSe<sub>2</sub>
Rhenium diselenide (ReSe2) is a layered indirect gap semiconductor for which micromechanical cleavage can produce monolayers consisting of a plane of rhenium atoms with selenium atoms above and below....
A Modular Bio-Platform Based on a Versatile Supramolecular Multi-Enzyme Complex Directly Attached to Graphene
Abeer Alshammari, Mareike G. Posner, Abhishek Upadhyay, Frank Marken, Stefan Bagby, Adelina Ilie
Aug 17, 2016
Developing generic strategies for building adaptable or multi-functional bio-platforms is challenging, in particular because protein immobilization onto surfaces often causes loss of protein function and multi-functionality...
Non-invasive, transdermal, path-selective and specific glucose monitoring via a graphene-based platform
Luca Lipani, Bertrand G. R. Dupont, Floriant Doungmene, Frank Marken, Rex M. Tyrrell, Richard H. Guy, Adelina Ilie
Jun 30, 2018
Currently, there is no available needle-free approach for diabetics to monitor glucose levels in the interstitial fluid. Here, we report a path-selective, non-invasive, transdermal glucose monitoring system based on a...
In Vivo Pretargeting Based on Cysteine-Selective Antibody Modification with IEDDA Bioorthogonal Handles for Click Chemistry.
Vera FC Ferreira, Bruno L Oliveira, Alice D'Onofrio, Carlos M Farinha, Lurdes Gano, António Paulo, Gonçalo JL Bernardes, Filipa Mendes
Dec 04, 2020
Pretargeted imaging has emerged as an effective multistep strategy aiming to improve imaging contrast and reduce patient radiation exposure through decoupling of the radioactivity from the targeting vector. The inverse...
The timing and widespread effects of the largest Holocene volcanic eruption in Antarctica.
Dermot Antoniades, Santiago Giralt, Adelina Geyer, Antonio M Álvarez-Valero, Sergi Pla-Rabes, Ignacio Granados, Emma J Liu, Manuel Toro, John L Smellie, Marc Oliva
Jan 08, 2019
The caldera collapse of Deception Island Volcano, Antarctica, was comparable in scale to some of the largest eruptions on Earth over the last several millennia. Despite its magnitude and potential for far-reaching environmental...
METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation.
Luca Pandolfini, Isaia Barbieri, Andrew J Bannister, Alan Hendrick, Byron Andrews, Natalie Webster, Pierre Murat, Pia Mach, Rossella Brandi, Samuel C Robson, Valentina Migliori, Andrej Alendar, Mara d'Onofrio, Shankar Balasubramanian, Tony Kouzarides
Apr 05, 2019
7-methylguanosine (m7G) is present at mRNA caps and at defined internal positions within tRNAs and rRNAs. However, its detection within low-abundance mRNAs and microRNAs (miRNAs) has been hampered by a lack of sensitive...
7-methylguanosine G-Quadruplexes METTL1 RNA methylation SAM-dependent methyltransferase cell migration high-throughput sequencing let-7 miRNA biogenesis microRNA A549 Cells Base Sequence Biological Assay Caco-2 Cells Cell Movement Cell Proliferation Guanosine HEK293 Cells Humans Methylation Methyltransferases MicroRNAs Nucleic Acid Conformation RNA processing Post-Transcriptional
Non-invasive, transdermal, path-selective and specific glucose monitoring via a graphene-based platform
Luca Lipani, Bertrand G. R. Dupont, Floriant Doungmene, Frank Marken, Rex M. Tyrrell, Richard H. Guy, Adelina Ilie
Jun 30, 2018
Currently, there is no available needle-free approach for diabetics to monitor glucose levels in the interstitial fluid. Here, we report a path-selective, non-invasive, transdermal glucose monitoring system based on a...
A roadmap to advance dementia research in prevention, diagnosis, intervention, and care by 2025.
James Pickett, Cathy Bird, Clive Ballard, Sube Banerjee, Carol Brayne, Katherine Cowan, Linda Clare, Adelina Comas-Herrera, Lynne Corner, Stephanie Daley, Martin Knapp, Louise Lafortune, Gill Livingston, Jill Manthorpe, Natalie Marchant, Jo Moriarty, Louise Robinson, Clare van Lynden, Gill Windle, Bob Woods, Katherine Gray, Clare Walton
Apr 04, 2018
OBJECTIVE: National and global dementia plans have focused on the research ambition to develop a cure or disease-modifying therapy by 2025, with the initial focus on investment in drug discovery approaches. We set out to develop...
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