Search
Results: 89
Breast cancer risk prediction using a polygenic risk score in the familial setting
Hongyan Li, Bingjian Feng, Alexander Miron, Xiaoqing Chen, Jonathan Beesley, Emmanuella Bimeh, Daniel Barrowdale, Esther M John, Mary B Daly, Irene L Andrulis, Saundra S Buys, Peter Kraft, kConFab Investigators, Heather Thorne, Georgia Chenevix-Trench, Melissa C Southey, Antonis C Antoniou, Paul A James, Mary Beth Terry, Kelly-Anne Phillips, John L Hopper, Gillian Mitchell, David E Goldgar
Jun 03, 2016
Accuracy of Risk Estimates from the iPrevent Breast Cancer Risk Assessment and Management Tool.
Kelly-Anne Phillips, Yuyan Liao, Roger L Milne, Robert J Macinnis, Ian M Collins, Richard Buchsbaum, Prue C Weideman, Adrian Bickerstaffe, Stephanie Nesci, Wendy K Chung, Melissa C Southey, Julia A Knight, Alice S Whittemore, Gillian S Dite, David Goldgar, Graham G Giles, Gord Glendon, Jack Cuzick, Antonis C Antoniou, Irene L Andrulis, Esther M John, Mary B Daly, Saundra S Buys, John L Hopper, Mary Beth Terry, kConFab Investigators
Aug 28, 2020
BACKGROUND: iPrevent is an online breast cancer (BC) risk management decision support tool. It uses an internal switching algorithm, based on a woman's risk factor data, to estimate her absolute BC risk using either the...
Age-specific breast cancer risk by body mass index and familial risk
John L Hopper, Gillian S Dite, Robert J Macinnis, Yuyan Liao, Nur Zeinomar, Julia A Knight, Melissa C Southey, Roger L Milne, Wendy K Chung, Graham G Giles, Jeanine M Genkinger, Sue-Anne McLachlan, Michael L Friedlander, Antonis C Antoniou, Prue C Weideman, Gord Glendon, Stephanie Nesci, kConFab Investigators, Irene L Andrulis, Saundra S Buys, Mary B Daly, Esther M John, Kelly Anne Phillips, Mary Beth Terry
Dec 04, 2018
BACKGROUND: The association between body mass index (BMI) and risk of breast cancer depends on time of life, but it is unknown whether this association depends on a woman's familial risk. METHODS: We conducted a prospective...
Body Mass Index Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm Breast Cancer familial risk Gene–environment interaction Adult Age Factors Aged Australia Body Mass Index Breast Neoplasms Canada Female Follow-Up Studies Humans Incidence Medical History Taking Middle Aged New Zealand Postmenopause Premenopause Prospective Studies Registries Risk Factors United States Young Adult
Development and validation of a targeted gene sequencing panel for application to disparate cancers.
Mark J McCabe, Marie-Emilie A Gauthier, Chia-Ling Chan, Tanya J Thompson, Sunita MC De Sousa, Clare Puttick, John P Grady, Velimir Gayevskiy, Jiang Tao, Kevin Ying, Arcadi Cipponi, Niantao Deng, Alex Swarbrick, Melissa L Thomas, Reginald V Lord, Amber L Johns, Maija Kohonen-Corish, Sandra A O'Toole, Jonathan Clark, Simon A Mueller, Ruta Gupta, Ann I McCormack, Marcel E Dinger, Mark J Cowley, kConFab
Nov 18, 2020
Next generation sequencing has revolutionised genomic studies of cancer, having facilitated the development of precision oncology treatments based on a tumour's molecular profile. We aimed to develop a targeted gene sequencing...
Biomarkers Tumor Carcinoma Pancreatic Ductal Cell Line Tumor Circulating Tumor DNA Computational Biology Genetic Predisposition to Disease Genomics Head and Neck Neoplasms High-Throughput Nucleotide Sequencing Humans Liquid biopsy Pancreatic Neoplasms Pituitary Neoplasms Precision Medicine Sensitivity and Specificity Squamous Cell Carcinoma of Head and Neck
The Landscape of Somatic Genetic Alterations in Breast Cancers From ATM Germline Mutation Carriers.
Britta Weigelt, Rui Bi, Rahul Kumar, Pedro Blecua, Diana L Mandelker, Felipe C Geyer, Fresia Pareja, Paul A James, kConFab Investigators, Fergus J Couch, Diana M Eccles, Fiona Blows, Paul Pharoah, Anqi Li, Pier Selenica, Raymond S Lim, Gowtham Jayakumaran, Nic Waddell, Ronglai Shen, Larry Norton, Hannah Y Wen, Simon N Powell, Nadeem Riaz, Mark E Robson, Jorge S Reis-Filho, Georgia Chenevix-Trench
Jul 26, 2018
Alleles Phenotype Mutation ataxia-telangiectasia hormone receptors brcal protein DNA DNA Damage Genes brcal gene tp53 gene Germ-Line Mutation Loss of Heterozygosity protein p53 Recombination Genetic Genetics Neoplasms Breast Cancer Somatic mutation biopharmaceutics classification system infiltrates cell cycle checkpoint Exome datasets
Etiology of hormone receptor positive breast cancer differs by levels of histologic grade and proliferation.
Mustapha Abubakar, Jenny Chang-Claude, H Raza Ali, Nilanjan Chatterjee, Penny Coulson, Frances Daley, Fiona Blows, Javier Benitez, Roger L Milne, Hermann Brenner, Christa Stegmaier, Arto Mannermaa, Anja Rudolph, Peter Sinn, Fergus J Couch, Peter Devilee, Rob AEM Tollenaar, Caroline Seynaeve, Jonine Figueroa, Jolanta Lissowska, Stephen Hewitt, Maartje J Hooning, Antoinette Hollestelle, Renée Foekens, Linetta B Koppert, kConFab Investigators, Manjeet K Bolla, Qin Wang, Michael E Jones, Minouk J Schoemaker, Renske Keeman, Douglas F Easton, Anthony J Swerdlow, Mark E Sherman, Marjanka K Schmidt, Paul D Pharoah, Montserrat Garcia-Closas
Apr 13, 2018
Limited epidemiological evidence suggests that the etiology of hormone receptor positive (HR+) breast cancer may differ by levels of histologic grade and proliferation. We pooled risk factor and pathology data on 5,905 HR+...
Ki67 Breast Cancer EPIDEMIOLOGY grade hormone therapy nulliparity obesity Proliferation Adult Aged Biomarkers Tumor Body Mass Index Breast Neoplasms Case-Control Studies Cell Proliferation Contraceptives Oral Hormonal Female Humans Ki-67 Antigen Middle Aged Neoplasm Grading obesity Parity Receptors Estrogen Receptors Progesterone Risk Factors
Risk-reducing salpingo-oophorectomy, natural menopause, and breast cancer risk
Nasim Mavaddat, Antonis C Antoniou, Thea M Mooij, Maartje J Hooning, Bernadette A Heemskerk-Gerritsen, GENEPSO, Catherine Noguès, Marion Gauthier-Villars, Olivier Caron, Paul Gesta, Pascal Pujol, Alain Lortholary, EMBRACE, Daniel Barrowdale, Debra Frost, D Gareth Evans, Louise Izatt, Julian Adlard, Ros Eeles, Carole Brewer, Marc Tischkowitz, Alex Henderson, Jackie Cook, Diana Eccles, HEBON, Klaartje van Engelen, Marian JE Mourits, Margreet Gem Ausems, Linetta B Koppert, John L Hopper, Esther M John, Wendy K Chung, Irene L Andrulis, Mary B Daly, Saundra S Buys, kConFab Investigators, Javier Benitez, Trinidad Caldes, Anna Jakubowska, Jacques Simard, Christian F Singer, Yen Tan, Edith Olah, Marie Navratilova, Lenka Foretova, Anne-Marie Gerdes, Marie-José Roos-Blom, Flora E van Leeuwen, Brita Arver, Håkan Olsson, Rita K Schmutzler, Christoph Engel, Karin Kast, Kelly-Anne Phillips, Mary Beth Terry, Roger L Milne, David E Goldgar, Matti A Rookus, Nadine Andrieu, Douglas F Easton, IBCCS, kConFab, BCFR
Feb 03, 2020
Gene-Environment Interactions Relevant to Estrogen and Risk of Breast Cancer
JooYong Park, Ji-Yeob Choi, Jaesung Choi, Seokang Chung, Nan Song, Sue K. Park, Wonshik Han, Dong-Young Noh, Sei-Hyun Ahn, Jong Won Lee, Mi Kyung Kim, Sun Ha Jee, Wanqing Wen, Manjeet K. Bolla, Qin Wang, Joe Dennis, Kyriaki Michailidou, Mitul Shah, Don M. Conroy, Patricia A. Harrington, Rebecca Mayes, Kamila Czene, Per Hall, Lauren R. Teras, Alpa V. Patel, Fergus J. Couch, Janet E. Olson, Elinor J. Sawyer, Rebecca Roylance, Stig E. Bojesen, Henrik Flyger, Diether Lambrechts, Adinda Baten, Keitaro Matsuo, Hidemi Ito, Pascal Guénel, Thérèse Truong, Renske Keeman, Marjanka K. Schmidt, Anna H. Wu, Chiu-Chen Tseng, Angela Cox, Simon S. Cross, kConFab Investigators kConFab Investigators, Irene L. Andrulis, John L. Hopper, Melissa C. Southey, Pei-Ei Wu, Chen-Yang Shen, Peter A. Fasching, Arif B. Ekici, Kenneth Muir, Artitaya Lophatananon, Hermann Brenner, Volker Arndt, Michael E. Jones, Anthony J. Swerdlow, Reiner Hoppe, Yon-Dschun Ko, Mikael Hartman, Jingmei Li, Arto Mannermaa, Jaana M. Hartikainen, Javier Benitez, Anna González-Neira, Christopher A. Haiman, Thilo Dörk, Natalia V. Bogdanova, Soo Hwang Teo, Nur Aishah Mohd Taib, Olivia Fletcher, Nichola Johnson, Mervi Grip, Robert Winqvist, Carl Blomqvist, Heli Nevanlinna, Annika Lindblom, Camilla Wendt, Vessela N. Kristensen, NBCS Collaborators NBCS Collaborators, Rob A. E. M. Tollenaar, Bernadette A. M. Heemskerk-Gerritsen, Paolo Radice, Bernardo Bonanni, Ute Hamann, Mehdi Manoochehri, James V. Lacey, Maria Elena Martinez, Alison M. Dunning, Paul D. P. Pharoah, Douglas F. Easton, Keun-Young Yoo, Daehee Kang
May 20, 2021
In this study we aim to examine gene–environment interactions (GxEs) between genes involved with estrogen metabolism and environmental factors related to estrogen exposure. GxE analyses were conducted with 1970 Korean breast...
Annexin A1 expression in a pooled breast cancer series
Marcelo Sobral-Leite, Jelle Wesseling, Vincent THBM Smit, Heli Nevanlinna, Martine H van Miltenburg, Joyce Sanders, Ingrid Hofland, Fiona M Blows, Penny Coulson, Gazinska Patrycja, Jan HM Schellens, Rainer Fagerholm, Päivi Heikkilä, Kristiina Aittomäki, Carl Blomqvist, Elena Provenzano, Hamid Raza Ali, Jonine Figueroa, Mark Sherman, Jolanta Lissowska, Arto Mannermaa, Vesa Kataja, Veli-Matti Kosma, Jaana M Hartikainen, Kelly-Anne Phillips, kConFab/AOCS Investigators, Fergus J Couch, Janet E Olson, Celine Vachon, Daniel Visscher, Hermann Brenner, Katja Butterbach, Volker Arndt, Bernd Holleczek, Maartje J Hooning, Antoinette Hollestelle, John WM Martens, Carolien HM van Deurzen, Bob van de Water, Annegien Broeks, Jenny Chang-Claude, Georgia Chenevix-Trench, Douglas F Easton, Paul DP Pharoah, Montserrat García-Closas, Marjo de Graauw, Marjanka K Schmidt
Jun 25, 2015
Homologous recombination DNA repair defects in PALB2-associated breast cancers.
Anqi Li, Felipe C Geyer, Pedro Blecua, Ju Youn Lee, Pier Selenica, David N Brown, Fresia Pareja, Simon SK Lee, Rahul Kumar, Barbara Rivera, Rui Bi, Salvatore Piscuoglio, Hannah Y Wen, John R Lozada, Rodrigo Gularte-Mérida, Luca Cavallone, kConFab Investigators, Zoulikha Rezoug, Tu Nguyen-Dumont, Paolo Peterlongo, Carlo Tondini, Thorkild Terkelsen, Karina Rønlund, Susanne E Boonen, Arto Mannerma, Robert Winqvist, Marketa Janatova, Pathmanathan Rajadurai, Bing Xia, Larry Norton, Mark E Robson, Pei-Sze Ng, Lai-Meng Looi, Melissa C Southey, Britta Weigelt, Teo Soo-Hwang, Marc Tischkowitz, William D Foulkes, Jorge S Reis-Filho
Jun 11, 2019
Association of germline variation with the survival of women with BRCA1/2 pathogenic variants and breast cancer.
Taru A Muranen, Sofia Khan, Rainer Fagerholm, Kristiina Aittomäki, Julie M Cunningham, Joe Dennis, Goska Leslie, Lesley McGuffog, Michael T Parsons, Jacques Simard, Susan Slager, Penny Soucy, Douglas F Easton, Marc Tischkowitz, Amanda B Spurdle, kConFab Investigators, Rita K Schmutzler, Barbara Wappenschmidt, Eric Hahnen, Maartje J Hooning, HEBON Investigators, Christian F Singer, Gabriel Wagner, Mads Thomassen, Inge Sokilde Pedersen, Susan M Domchek, Katherine L Nathanson, Conxi Lazaro, Caroline Maria Rossing, Irene L Andrulis, Manuel R Teixeira, Paul James, Judy Garber, Jeffrey N Weitzel, SWE-BRCA Investigators, Anna Jakubowska, Drakoulis Yannoukakos, Esther M John, Melissa C Southey, Marjanka K Schmidt, Antonis C Antoniou, Georgia Chenevix-Trench, Carl Blomqvist, Heli Nevanlinna
Aug 28, 2020
Germline genetic variation has been suggested to influence the survival of breast cancer patients independently of tumor pathology. We have studied survival associations of genetic variants in two etiologically unique groups of...
Common Susceptibility Loci for Male Breast Cancer.
Sarah Maguire, Eleni Perraki, Katarzyna Tomczyk, Michael E Jones, Olivia Fletcher, Matthew Pugh, Timothy Winter, Kyle Thompson, Rosie Cooke, kConFab Consortium, Alison Trainer, Paul James, Stig Bojesen, Henrik Flyger, Heli Nevanlinna, Johanna Mattson, Eitan Friedman, Yael Laitman, Domenico Palli, Giovanna Masala, Ines Zanna, Laura Ottini, Valentina Silvestri, Antoinette Hollestelle, Maartje J Hooning, Srdjan Novaković, Mateja Krajc, Manuela Gago-Dominguez, Jose Esteban Castelao, Hakan Olsson, Ingrid Hedenfalk, Emmanouil Saloustros, Vasilios Georgoulias, Douglas F Easton, Paul Pharoah, Alison M Dunning, D Timothy Bishop, Susan L Neuhausen, Linda Steele, Alan Ashworth, Montserrat Garcia Closas, Richard Houlston, Anthony Swerdlow, Nick Orr
Oct 16, 2020
BACKGROUND: The etiology of male breast cancer (MBC) is poorly understood. In particular, the extent to which the genetic basis of MBC differs from female breast cancer (FBC) is unknown. A previous genome-wide association study...
Evaluation of copy-number variants as modifiers of breast and ovarian cancer risk for BRCA1 pathogenic variant carriers.
LC Walker, L Marquart, JF Pearson, GAR Wiggins, TA O'Mara, MT Parsons, BCFR, D Barrowdale, L McGuffog, J Dennis, J Benitez, TP Slavin, P Radice, D Frost, EMBRACE, AK Godwin, A Meindl, RK Schmutzler, GEMO Study Collaborators, C Isaacs, BN Peshkin, T Caldes, FB Hogervorst, HEBON, C Lazaro, A Jakubowska, M Montagna, kConFab Investigators, X Chen, K Offit, PJ Hulick, IL Andrulis, A Lindblom, RL Nussbaum, KL Nathanson, G Chenevix-Trench, AC Antoniou, FJ Couch, AB Spurdle
Mar 08, 2017
TP53-based interaction analysis identifies cis-eQTL variants for TP53BP2, FBXO28, and FAM53A that associate with survival and treatment outcome in breast cancer.
R Fagerholm, S Khan, MK Schmidt, M García-Closas, P Heikkilä, J Saarela, J Beesley, M Jamshidi, K Aittomäki, J Liu, HR Ali, IL Andrulis, MW Beckmann, S Behrens, FM Blows, H Brenner, J Chang-Claude, FJ Couch, K Czene, PA Fasching, J Figueroa, G Floris, G Glendon, Q Guo, P Hall, E Hallberg, U Hamann, B Holleczek, MJ Hooning, JL Hopper, A Jager, M Kabisch, kConFab/AOCS Investigators, R Keeman, V-M Kosma, D Lambrechts, A Lindblom, A Mannermaa, S Margolin, E Provenzano, M Shah, MC Southey, J Dennis, M Lush, K Michailidou, Q Wang, MK Bolla, AM Dunning, DF Easton, PDP Pharoah, G Chenevix-Trench, C Blomqvist, H Nevanlinna
Mar 16, 2017
Prognostic value of automated KI67 scoring in breast cancer
Mustapha Abubakar, Nick Orr, Frances Daley, Penny Coulson, H Raza Ali, Fiona Blows, Javier Benitez, Roger Milne, Herman Brenner, Christa Stegmaier, Arto Mannermaa, Jenny Chang-Claude, Anja Rudolph, Peter Sinn, Fergus J Couch, Peter Devilee, Rob AEM Tollenaar, Caroline Seynaeve, Jonine Figueroa, Mark E Sherman, Jolanta Lissowska, Stephen Hewitt, Diana Eccles, Maartje J Hooning, Antoinette Hollestelle, John WM Martens, Carolien HM van Deurzen, kConFab Investigators, Manjeet K Bolla, Qin Wang, Michael Jones, Minouk Schoemaker, Jelle Wesseling, Flora E van Leeuwen, Laura van 't Veer, Douglas Easton, Anthony J Swerdlow, Mitch Dowsett, Paul D Pharoah, Marjanka K Schmidt, Montserrat Garcia-Closas
May 02, 2019
BACKGROUND: The value of KI67 in breast cancer prognostication has been questioned due to concerns on the analytical validity of visual KI67 assessment and methodological limitations of published studies. Here, we investigate...
Automated KI67 Breast Cancer prognostication Visual KI67 Adult Aged Aged 80 and over Biomarkers Tumor Breast Neoplasms Female Humans Immunohistochemistry Kaplan-Meier Estimate Ki-67 Antigen Middle Aged Neoplasm Grading Neoplasm Staging Population Surveillance Prognosis Proportional Hazards Models Young Adult
Ovarian and Breast Cancer Risks Associated With Pathogenic Variants in RAD51C and RAD51D.
Xin Yang, Honglin Song, Goska Leslie, Christoph Engel, Eric Hahnen, Bernd Auber, Judit Horváth, Karin Kast, Dieter Niederacher, Clare Turnbull, Richard Houlston, Helen Hanson, Chey Loveday, Jill S Dolinsky, Holly LaDuca, Susan J Ramus, Usha Menon, Adam N Rosenthal, Ian Jacobs, Simon A Gayther, Ed Dicks, Heli Nevanlinna, Kristiina Aittomäki, Liisa M Pelttari, Hans Ehrencrona, Åke Borg, Anders Kvist, Barbara Rivera, Thomas vO Hansen, Malene Djursby, Andrew Lee, Joe Dennis, David D Bowtell, Nadia Traficante, Orland Diez, Judith Balmaña, Stephen B Gruber, Georgia Chenevix-Trench, KConFaB Investigators, Allan Jensen, Susanne K Kjaer, Estrid Høgdall, Laurent Castéra, Judy Garber, Ramunas Janavicius, Ana Osorio, Lisa Golmard, Ana Vega, Fergus J Couch, Mark Robson, Jacek Gronwald, Susan M Domchek, Julie O Culver, Miguel de la Hoya, Douglas F Easton, William D Foulkes, Marc Tischkowitz, Alfons Meindl, Rita K Schmutzler, Paul DP Pharoah, Antonis C Antoniou
Feb 20, 2020
BACKGROUND: The purpose of this study was to estimate precise age-specific tubo-ovarian carcinoma (TOC) and breast cancer (BC) risks for carriers of pathogenic variants in RAD51C and RAD51D. METHODS: We analyzed data from 6178...
Whole-genome sequencing reveals clinically relevant insights into the aetiology of familial breast cancers.
K Nones, J Johnson, F Newell, AM Patch, H Thorne, SH Kazakoff, XM de Luca, MT Parsons, K Ferguson, LE Reid, AE McCart Reed, S Srihari, V Lakis, AL Davidson, P Mukhopadhyay, O Holmes, Q Xu, S Wood, C Leonard, Kathleen Cuningham Foundation Consortium for Research into Familial Aspects of Breast Cancer (kConFab), Australian Breast Cancer Tissue Bank (ABCTB), Brisbane Breast Bank (BBB), J Beesley, JM Harris, D Barnes, A Degasperi, MA Ragan, AB Spurdle, KK Khanna, SR Lakhani, JV Pearson, S Nik-Zainal, G Chenevix-Trench, N Waddell, PT Simpson
May 23, 2019
BACKGROUND: Whole-genome sequencing (WGS) is a powerful method for revealing the diversity and complexity of the somatic mutation burden of tumours. Here, we investigated the utility of tumour and matched germline WGS for...
BRCA1 BRCA2 familial breast cancers mutation signatures whole-genome sequencing Adult BRCA1 Protein BRCA2 Protein Breast Neoplasms DNA Neoplasm Fanconi Anemia Complementation Group N Protein Female Genetic Predisposition to Disease Germ-Line Mutation Humans Middle Aged Prognosis whole genome sequencing
Correction
Logan C Walker, Louise Marquart, John F Pearson, George AR Wiggins, Tracy A O'Mara, Michael T Parsons, BCFR, Daniel Barrowdale, Lesley McGuffog, Joe Dennis, Javier Benitez, Thomas P Slavin, Paolo Radice, Debra Frost, EMBRACE, Andrew K Godwin, Alfons Meindl, Rita Katharina Schmutzler, GEMO Study Collaborators, Claudine Isaacs, Beth N Peshkin, Trinidad Caldes, Frans BL Hogervorst, HEBON, Conxi Lazaro, Anna Jakubowska, Marco Montagna, kConFab Investigators, Xiaoqing Chen, Kenneth Offit, Peter J Hulick, Irene L Andrulis, Annika Lindblom, Robert L Nussbaum, Katherine L Nathanson, Georgia Chenevix-Trench, Antonis C Antoniou, Fergus J Couch, Amanda B Spurdle
Oct 03, 2018
This Article was originally published under a CC BY-NC-SA 4.0 license, but has now been made available under a CC BY 4.0 license. The PDF and HTML versions of the Article have been modified accordingly.
Effects of BRCA2 cis-regulation in normal breast and cancer risk amongst BRCA2 mutation carriers.
Ana-Teresa Maia, Antonis C Antoniou, Martin O'Reilly, Shamith Samarajiwa, Mark Dunning, Christiana Kartsonaki, Suet-Feung Chin, Christina N Curtis, Lesley McGuffog, Susan M Domchek, EMBRACE, Douglas F Easton, Susan Peock, Debra Frost, D Gareth Evans, Ros Eeles, Louise Izatt, Julian Adlard, Diana Eccles, GEMO Study Collaborators, Olga M Sinilnikova, Sylvie Mazoyer, Dominique Stoppa-Lyonnet, Marion Gauthier-Villars, Laurence Faivre, Laurence Venat-Bouvet, Capucine Delnatte, Heli Nevanlinna, Fergus J Couch, Andrew K Godwin, Maria Adelaide Caligo, SWE-BRCA, Rosa B Barkardottir, kConFab Investigators, Xiaoqing Chen, Jonathan Beesley, Sue Healey, Carlos Caldas, Georgia Chenevix-Trench, Bruce AJ Ponder
May 17, 2012
High-throughput automated scoring of Ki67 in breast cancer tissue microarrays from the Breast Cancer Association Consortium.
Mustapha Abubakar, William J Howat, Frances Daley, Lila Zabaglo, Leigh-Anne McDuffus, Fiona Blows, Penny Coulson, H Raza Ali, Javier Benitez, Roger Milne, Herman Brenner, Christa Stegmaier, Arto Mannermaa, Jenny Chang-Claude, Anja Rudolph, Peter Sinn, Fergus J Couch, Rob AEM Tollenaar, Peter Devilee, Jonine Figueroa, Mark E Sherman, Jolanta Lissowska, Stephen Hewitt, Diana Eccles, Maartje J Hooning, Antoinette Hollestelle, John Wm Martens, Carolien Hm van Deurzen, kConFab Investigators, Manjeet K Bolla, Qin Wang, Michael Jones, Minouk Schoemaker, Annegien Broeks, Flora E van Leeuwen, Laura Van't Veer, Anthony J Swerdlow, Nick Orr, Mitch Dowsett, Douglas Easton, Marjanka K Schmidt, Paul D Pharoah, Montserrat Garcia-Closas
May 17, 2016
Alcohol Consumption, Cigarette Smoking, and Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers
Hongyan Li, Mary Beth Terry, Antonis C Antoniou, Kelly-Anne Phillips, Karin Kast, Thea M Mooij, Christoph Engel, Catherine Noguès, Dominique Stoppa-Lyonnet, Christine Lasset, Pascaline Berthet, Veronique Mari, Olivier Caron, GENEPSO study, Daniel Barrowdale, Debra Frost, Carole Brewer, D Gareth Evans, Louise Izatt, Lucy Side, Lisa Walker, Marc Tischkowitz, Mark T Rogers, Mary E Porteous, Katie Snape, EMBRACE Study, Hanne EJ Meijers-Heijboer, Johan JP Gille, Marinus J Blok, Nicoline Hoogerbrugge, HEBON Investigators, Mary B Daly, Irene L Andrulis, Saundra S Buys, Esther M John, Sue-Anne McLachlan, Michael Friedlander, kConFab Investigators, Yen Y Tan, Ana Osorio, Trinidad Caldes, Anna Jakubowska, Jacques Simard, Christian F Singer, Edith Olah, Marie Navratilova, Lenka Foretova, Anne-Marie Gerdes, Marie-José Roos-Blom, Brita Arver, Håkan Olsson, Rita K Schmutzler, John L Hopper, Roger L Milne, Douglas F Easton, Flora E van Leeuwen, Matti A Rookus, Nadine Andrieu, David E Goldgar
Dec 04, 2019
BACKGROUND: Tobacco smoking and alcohol consumption have been intensively studied in the general population to assess their effects on the risk of breast cancer, but very few studies have examined these effects in BRCA1 and...
Combined genetic and splicing analysis of BRCA1 c.[594-2A>C; 641A>G] highlights the relevance of naturally occurring in-frame transcripts for developing disease gene variant classification algorithms.
Miguel de la Hoya, Omar Soukarieh, Irene López-Perolio, Ana Vega, Logan C Walker, Yvette van Ierland, Diana Baralle, Marta Santamariña, Vanessa Lattimore, Juul Wijnen, Philip Whiley, Ana Blanco, Michela Raponi, Jan Hauke, Barbara Wappenschmidt, Alexandra Becker, Thomas vO Hansen, Raquel Behar, KConFaB Investigators, Diether Niederacher, Norbert Arnold, Bernd Dworniczak, Doris Steinemann, Ulrike Faust, Wendy Rubinstein, Peter J Hulick, Claude Houdayer, Sandrine M Caputo, Laurent Castera, Tina Pesaran, Elizabeth Chao, Carole Brewer, Melissa C Southey, Christi J van Asperen, Christian F Singer, Jan Sullivan, Nicola Poplawski, Phuong Mai, Julian Peto, Nichola Johnson, Barbara Burwinkel, Harald Surowy, Stig E Bojesen, Henrik Flyger, Annika Lindblom, Sara Margolin, Jenny Chang-Claude, Anja Rudolph, Paolo Radice, Laura Galastri, Janet E Olson, Emily Hallberg, Graham G Giles, Roger L Milne, Irene L Andrulis, Gord Glendon, Per Hall, Kamila Czene, Fiona Blows, Mitul Shah, Qin Wang, Joe Dennis, Kyriaki Michailidou, Lesley McGuffog, Manjeet K Bolla, Antonis C Antoniou, Douglas F Easton, Fergus J Couch, Sean Tavtigian, Maaike P Vreeswijk, Michael Parsons, Huong D Meeks, Alexandra Martins, David E Goldgar, Amanda B Spurdle
May 18, 2016
Genetic variation in the immunosuppression pathway genes and breast cancer susceptibility
Jieping Lei, Anja Rudolph, Kirsten B Moysich, Sabine Behrens, Ellen L Goode, Manjeet K Bolla, Joe Dennis, Alison M Dunning, Douglas F Easton, Qin Wang, Javier Benitez, John L Hopper, Melissa C Southey, Marjanka K Schmidt, Annegien Broeks, Peter A Fasching, Lothar Haeberle, Julian Peto, Isabel dos-Santos-Silva, Elinor J Sawyer, Ian Tomlinson, Barbara Burwinkel, Frederik Marmé, Pascal Guénel, Thérèse Truong, Stig E Bojesen, Henrik Flyger, Sune F Nielsen, Børge G Nordestgaard, Anna González-Neira, Primitiva Menéndez, Hoda Anton-Culver, Susan L Neuhausen, Hermann Brenner, Volker Arndt, Alfons Meindl, Rita K Schmutzler, Hiltrud Brauch, Ute Hamann, Heli Nevanlinna, Rainer Fagerholm, Thilo Dörk, Natalia V Bogdanova, Arto Mannermaa, Jaana M Hartikainen, Australian Ovarian Study Group, kConFab Investigators, Laurien Van Dijck, Ann Smeets, Dieter Flesch-Janys, Ursula Eilber, Paolo Radice, Paolo Peterlongo, Fergus J Couch, Emily Hallberg, Graham G Giles, Roger L Milne, Christopher A Haiman, Fredrick Schumacher, Jacques Simard, Mark S Goldberg, Vessela Kristensen, Anne-Lise Borresen-Dale, Wei Zheng, Alicia Beeghly-Fadiel, Robert Winqvist, Mervi Grip, Irene L Andrulis, Gord Glendon, Montserrat García-Closas, Jonine Figueroa, Kamila Czene, Judith S Brand, Hatef Darabi, Mikael Eriksson, Per Hall, Jingmei Li, Angela Cox, Simon S Cross, Paul DP Pharoah, Mitul Shah, Maria Kabisch, Diana Torres, Anna Jakubowska, Jan Lubinski, Foluso Ademuyiwa, Christine B Ambrosone, Anthony Swerdlow, Michael Jones, Jenny Chang-Claude
Jan 15, 2016
Association of breast cancer risk with genetic variants showing differential allelic expression
Y Hamdi, P Soucy, V Adoue, K Michailidou, S Canisius, A Lemaçon, A Droit, IL Andrulis, H Anton-Culver, V Arndt, C Baynes, C Blomqvist, NV Bogdanova, SE Bojesen, MK Bolla, B Bonanni, A-L Borresen-Dale, JS Brand, H Brauch, H Brenner, A Broeks, B Burwinkel, J Chang-Claude, N Collaborators, FJ Couch, A Cox, SS Cross, K Czene, H Darabi, J Dennis, P Devilee, T Dörk, I Dos-Santos-Silva, M Eriksson, PA Fasching, J Figueroa, H Flyger, M García-Closas, GG Giles, MS Goldberg, A González-Neira, G Grenaker-Alnæs, P Guénel, L Haeberle, CA Haiman, U Hamann, E Hallberg, MJ Hooning, JL Hopper, A Jakubowska, M Jones, M Kabisch, V Kataja, D Lambrechts, L Le Marchand, A Lindblom, J Lubinski, A Mannermaa, M Maranian, S Margolin, F Marme, RL Milne, SL Neuhausen, H Nevanlinna, P Neven, C Olswold, J Peto, D Plaseska-Karanfilska, K Pylkäs, P Radice, A Rudolph, EJ Sawyer, MK Schmidt, X-O Shu, MC Southey, A Swerdlow, RAEM Tollenaar, I Tomlinson, D Torres, T Truong, C Vachon, AMW van den Ouweland, Q Wang, R Winqvist, kConFab/AOCS Investigators, W Zheng, J Benitez, G Chenevix-Trench, AM Dunning, PDP Pharoah, V Kristensen, P Hall, DF Easton, T Pastinen, S Nord, J Simard
Dec 20, 2016
Genetic modifiers of CHEK2*1100delC-associated breast cancer risk.
Taru A Muranen, Dario Greco, Carl Blomqvist, Kristiina Aittomäki, Sofia Khan, Frans Hogervorst, Senno Verhoef, Paul DP Pharoah, Alison M Dunning, Mitul Shah, Robert Luben, Stig E Bojesen, Børge G Nordestgaard, Minouk Schoemaker, Anthony Swerdlow, Montserrat García-Closas, Jonine Figueroa, Thilo Dörk, Natalia V Bogdanova, Per Hall, Jingmei Li, Elza Khusnutdinova, Marina Bermisheva, Vessela Kristensen, Anne-Lise Borresen-Dale, NBCS Investigators, Julian Peto, Isabel Dos Santos Silva, Fergus J Couch, Janet E Olson, Peter Hillemans, Tjoung-Won Park-Simon, Hiltrud Brauch, Ute Hamann, Barbara Burwinkel, Frederik Marme, Alfons Meindl, Rita K Schmutzler, Angela Cox, Simon S Cross, Elinor J Sawyer, Ian Tomlinson, Diether Lambrechts, Matthieu Moisse, Annika Lindblom, Sara Margolin, Antoinette Hollestelle, John WM Martens, Peter A Fasching, Matthias W Beckmann, Irene L Andrulis, Julia A Knight, kConFab/AOCS Investigators, Hoda Anton-Culver, Argyrios Ziogas, Graham G Giles, Roger L Milne, Hermann Brenner, Volker Arndt, Arto Mannermaa, Veli-Matti Kosma, Jenny Chang-Claude, Anja Rudolph, Peter Devilee, Caroline Seynaeve, John L Hopper, Melissa C Southey, Esther M John, Alice S Whittemore, Manjeet K Bolla, Qin Wang, Kyriaki Michailidou, Joe Dennis, Douglas F Easton, Marjanka K Schmidt, Heli Nevanlinna
Sep 21, 2016
|
|< |
< |
1 |