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Results: 99458
Estimating prevalence of subjective cognitive decline in and across international cohort studies of aging
Susanne Röhr, Alexander Pabst, Steffi G Riedel-Heller, Frank Jessen, Yuda Turana, Yvonne S Handajani, Carol Brayne, Fiona E Matthews, Blossom CM Stephan, Richard B Lipton, Mindy J Katz, Cuiling Wang, Maëlenn Guerchet, Pierre-Marie Preux, Pascal Mbelesso, Karen Ritchie, Marie-Laure Ancelin, Isabelle Carrière, Antonio Guaita, Annalisa Davin, Roberta Vaccaro, Ki Woong Kim, Ji Won Han, Seung Wan Suh, Suzana Shahar, Normah C Din, Divya Vanoh, Martin van Boxtel, Sebastian Köhler, Mary Ganguli, Erin P Jacobsen, Beth E Snitz, Kaarin J Anstey, Nicolas Cherbuin, Shuzo Kumagai, Sanmei Chen, Kenji Narazaki, Tze Pin Ng, Qi Gao, Xinyi Gwee, Henry Brodaty, Nicole A Kochan, Julian Trollor, Antonio Lobo, Raúl López-Antón, Javier Santabárbara, John D Crawford, Darren M Lipnicki, Perminder S Sachdev, for Cohort Studies of Memory in an International Consortium (COSMIC)
Jan 04, 2021
The International Human Epigenome Consortium
The International Human Epigenome Consortium (IHEC) coordinates the generation of a catalog of high-resolution reference epigenomes of major primary human cell types. The studies now presented (see the Cell Press IHEC web portal...
Determinants of cognitive performance and decline in 20 diverse ethno-regional groups
Darren M Lipnicki, Steve R Makkar, John D Crawford, Anbupalam Thalamuthu, Nicole A Kochan, Maria Fernanda Lima-Costa, Erico Castro-Costa, Cleusa Pinheiro Ferri, Carol Brayne, Blossom Stephan, Juan J Llibre-Rodriguez, Jorge J Llibre-Guerra, Adolfo J Valhuerdi-Cepero, Richard B Lipton, Mindy J Katz, Carol A Derby, Karen Ritchie, Marie-Laure Ancelin, Isabelle Carrière, Nikolaos Scarmeas, Mary Yannakoulia, Georgios M Hadjigeorgiou, Linda Lam, Wai-Chi Chan, Ada Fung, Antonio Guaita, Roberta Vaccaro, Annalisa Davin, Ki Woong Kim, Ji Won Han, Seung Wan Suh, Steffi G Riedel-Heller, Susanne Roehr, Alexander Pabst, Martin van Boxtel, Sebastian Köhler, Kay Deckers, Mary Ganguli, Erin P Jacobsen, Tiffany F Hughes, Kaarin J Anstey, Nicolas Cherbuin, Mary N Haan, Allison E Aiello, Kristina Dang, Shuzo Kumagai, Tao Chen, Kenji Narazaki, Tze Pin Ng, Qi Gao, Ma Shwe Zin Nyunt, Marcia Scazufca, Henry Brodaty, Katya Numbers, Julian N Trollor, Kenichi Meguro, Satoshi Yamaguchi, Hiroshi Ishii, Antonio Lobo, Raul Lopez-Anton, Javier Santabárbara, Yvonne Leung, Jessica W Lo, Gordana Popovic, Perminder S Sachdev, for Cohort Studies of Memory in an International Consortium (COSMIC)
Sep 03, 2019
BACKGROUND: With no effective treatments for cognitive decline or dementia, improving the evidence base for modifiable risk factors is a research priority. This study investigated associations between risk factors and late-life...
Age-related cognitive decline and associations with sex, education and apolipoprotein E genotype across ethnocultural groups and geographic regions
Darren M Lipnicki, John D Crawford, Rajib Dutta, Anbupalam Thalamuthu, Nicole A Kochan, Gavin Andrews, M Fernanda Lima-Costa, Erico Castro-Costa, Carol Brayne, Fiona E Matthews, Blossom CM Stephan, Richard B Lipton, Mindy J Katz, Karen Ritchie, Jacqueline Scali, Marie-Laure Ancelin, Nikolaos Scarmeas, Mary Yannakoulia, Efthimios Dardiotis, Linda CW Lam, Candy HY Wong, Ada WT Fung, Antonio Guaita, Roberta Vaccaro, Annalisa Davin, Ki Woong Kim, Ji Won Han, Tae Hui Kim, Kaarin J Anstey, Nicolas Cherbuin, Peter Butterworth, Marcia Scazufca, Shuzo Kumagai, Sanmei Chen, Kenji Narazaki, Tze Pin Ng, Qi Gao, Simone Reppermund, Henry Brodaty, Antonio Lobo, Raúl Lopez-Anton, Javier Santabárbara, Perminder S Sachdev, Cohort Studies of Memory in an International Consortium (COSMIC)
Jan 16, 2018
BACKGROUND: The prevalence of dementia varies around the world, potentially contributed to by international differences in rates of age-related cognitive decline. Our primary goal was to investigate how rates of age-related...
Estimating prevalence of subjective cognitive decline in and across international cohort studies of aging
Susanne Röhr, Alexander Pabst, Steffi G. Riedel-Heller, Frank Jessen, Yuda Turana, Yvonne S. Handajani, Carol Brayne, Fiona E. Matthews, Blossom C. M. Stephan, Richard B. Lipton, Mindy J. Katz, Cuiling Wang, Maëlenn Guerchet, Pierre-Marie Preux, Pascal Mbelesso, Karen Ritchie, Marie-Laure Ancelin, Isabelle Carrière, Antonio Guaita, Annalisa Davin, Roberta Vaccaro, Ki Woong Kim, Ji Won Han, Seung Wan Suh, Suzana Shahar, Normah C. Din, Divya Vanoh, Martin van Boxtel, Sebastian Köhler, Mary Ganguli, Erin P. Jacobsen, Beth E. Snitz, Kaarin J. Anstey, Nicolas Cherbuin, Shuzo Kumagai, Sanmei Chen, Kenji Narazaki, Tze Pin Ng, Qi Gao, Xinyi Gwee, Henry Brodaty, Nicole A. Kochan, Julian Trollor, Antonio Lobo, Raúl López-Antón, Javier Santabárbara, John D. Crawford, Darren M. Lipnicki, Perminder S. Sachdev
Dec 22, 2020
Abstract: Background: Subjective cognitive decline (SCD) is recognized as a risk stage for Alzheimer’s disease (AD) and other dementias, but its prevalence is not well known. We aimed to use uniform criteria to better estimate...
ICC-dementia (International Centenarian Consortium - dementia)
Henry Brodaty, Claudia Woolf, Stacy Andersen, Nir Barzilai, Carol Brayne, Karen Siu-Lan Cheung, Maria M Corrada, John D Crawford, Catriona Daly, Yasuyuki Gondo, Bo Hagberg, Nobuyoshi Hirose, Henne Holstege, Claudia Kawas, Jeffrey Kaye, Nicole A Kochan, Bobo Hi-Po Lau, Ugo Lucca, Gabriella Marcon, Peter Martin, Leonard W Poon, Robyn Richmond, Jean-Marie Robine, Ingmar Skoog, Melissa J Slavin, Jan Szewieczek, Mauro Tettamanti, José Viña, Thomas Perls, Perminder S Sachdev
Sep 29, 2016
BACKGROUND: Considerable variability exists in international prevalence and incidence estimates of dementia. The accuracy of estimates of dementia in the oldest-old and the controversial question of whether dementia incidence...
Rare variant analysis of 4241 pulmonary arterial hypertension cases from an international consortium implicates FBLN2, PDGFD, and rare de novo variants in PAH.
Na Zhu, Emilia M Swietlik, Carrie L Welch, Michael W Pauciulo, Jacob J Hagen, Xueya Zhou, Yicheng Guo, Johannes Karten, Divya Pandya, Tobias Tilly, Katie A Lutz, Jennifer M Martin, Carmen M Treacy, Erika B Rosenzweig, Usha Krishnan, Anna W Coleman, Claudia Gonzaga-Jauregui, Allan Lawrie, Richard C Trembath, Martin R Wilkins, Regeneron Genetics Center, PAH Biobank Enrolling Centers’ Investigators, NIHR BioResource for Translational Research - Rare Diseases, National Cohort Study of Idiopathic and Heritable PAH, Nicholas W Morrell, Yufeng Shen, Stefan Gräf, William C Nichols, Wendy K Chung
Jul 28, 2021
BACKGROUND: Pulmonary arterial hypertension (PAH) is a lethal vasculopathy characterized by pathogenic remodeling of pulmonary arterioles leading to increased pulmonary pressures, right ventricular hypertrophy, and heart...
Case-control association testing De novo variant analysis Exome Sequencing Genetics genome sequencing pulmonary arterial hypertension Adolescent Adult Age of Onset Aged Alleles Amino Acid Substitution Biomarkers Calcium-Binding Proteins Child Child Preschool Extracellular Matrix Proteins Female Genetic Predisposition to Disease genetic variation Genotype Humans Lymphokines Male Middle Aged Mutation Phenotype Platelet-Derived Growth Factor Population Surveillance pulmonary arterial hypertension United Kingdom United States Young Adult
The IPASC data format
Janek Gröhl, Lina Hacker, Ben T Cox, Kris K Dreher, Stefan Morscher, Avotra Rakotondrainibe, François Varray, Lawrence CM Yip, William C Vogt, Sarah E Bohndiek, Members of the International Photoacoustic Standardisation Consortium (IPASC)
Apr 19, 2022
Photoacoustic imaging (PAI) is an emerging modality that has shown promise for improving patient management in a range of applications. Unfortunately, the current lack of uniformity in PAI data formats compromises inter-user...
Assessment of Disease Activity in Large-vessel Vasculitis
Sibel Z Aydin, Haner Direskeneli, Peter A Merkel, International Delphi on Disease Activity Assessment in Large-vessel Vasculitis
Mar 06, 2020
OBJECTIVE: To arrive at consensus for candidate outcomes for disease activity assessment in large-vessel vasculitis (LVV) in clinical trials. METHODS: A Delphi survey including 99 items was circulated among international experts...
Oral contraceptive use and ovarian cancer risk for BRCA1/2 mutation carriers
Lieske H Schrijver, Antonis C Antoniou, Håkan Olsson, Thea M Mooij, Marie-José Roos-Blom, Leyla Azarang, Julian Adlard, Munaza Ahmed, Daniel Barrowdale, Rosemarie Davidson, Alan Donaldson, Ros Eeles, D Gareth Evans, Debra Frost, Alex Henderson, Louise Izatt, Kai-Ren Ong, Valérie Bonadona, Isabelle Coupier, Laurence Faivre, Jean-Pierre Fricker, Paul Gesta, Klaartje van Engelen, Agnes Jager, Fred H Menko, Marian JE Mourits, Christian F Singer, Yen Y Tan, Lenka Foretova, Marie Navratilova, Rita K Schmutzler, Carolina Ellberg, Anne-Marie Gerdes, Trinidad Caldes, Jacques Simard, Edith Olah, Anna Jakubowska, Johanna Rantala, Ana Osorio, John L Hopper, Kelly-Anne Phillips, Roger L Milne, Mary Beth Terry, Catherine Noguès, Christoph Engel, Karin Kast, David E Goldgar, Flora E van Leeuwen, Douglas F Easton, Nadine Andrieu, Matti A Rookus, Gene Etude Prospective Sein Ovaire Sein, Hereditary Breast and Ovarian Cancer Research Group Netherlands, and International BRCA1/2 Carrier Cohort Study Epidemiological Study of Familial Breast Cancer
Apr 21, 2021
BACKGROUND: Ovarian cancer risk in BRCA1 and BRCA2 mutation carriers has been shown to decrease with longer duration of oral contraceptive use. Although the effects of using oral contraceptives in the general population are well...
Epidemiological Study of Familial Breast Cancer Gene Etude Prospective Sein Ovaire Sein Hereditary Breast and Ovarian Cancer Research Group Netherlands Humans Ovarian Neoplasms Genetic Predisposition to Disease Contraceptives Oral BRCA1 Protein BRCA2 Protein Proportional Hazards Models Retrospective Studies Cohort Studies Follow-Up Studies Mutation Adult Middle Aged Europe Female
External validation and recalibration of an incidental meningioma prognostic model - IMPACT
Abdurrahman I Islim, Christopher P Millward, Rory J Piper, Daniel M Fountain, Shaveta Mehta, Ruwanthi Kolamunnage-Dona, Usama Ali, Shelli Diane Koszdin, Theo Georgious, Samantha J Mills, Andrew R Brodbelt, Ryan K Mathew, Thomas Santarius, Michael D Jenkinson, International Consortium on Meningioma (ICOM) and British Neurosurgical Trainee Research Collaborative (BNTRC) IMPACT Study Investigators
Feb 19, 2022
INTRODUCTION: Due to the increased use of CT and MRI, the prevalence of incidental findings on brain scans is increasing. Meningioma, the most common primary brain tumour, is a frequently encountered incidental finding, with an...
External validation and recalibration of an incidental meningioma prognostic model - IMPACT
Abdurrahman I Islim, Christopher P Millward, Rory J Piper, Daniel M Fountain, Shaveta Mehta, Ruwanthi Kolamunnage-Dona, Usama Ali, Shelli Diane Koszdin, Theo Georgious, Samantha J Mills, Andrew R Brodbelt, Ryan K Mathew, Thomas Santarius, Michael D Jenkinson, International Consortium on Meningioma (ICOM) and British Neurosurgical Trainee Research Collaborative (BNTRC) IMPACT Study Investigators
Jan 28, 2022
INTRODUCTION: Due to the increased use of CT and MRI, the prevalence of incidental findings on brain scans is increasing. Meningioma, the most common primary brain tumour, is a frequently encountered incidental finding, with an...
Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases.
Raffaele Ferrari, Yunpeng Wang, Jana Vandrovcova, Sebastian Guelfi, Aree Witeolar, Celeste M Karch, Andrew J Schork, Chun C Fan, James B Brewer, International FTD-Genomics Consortium (IFGC), International Parkinson's Disease Genomics Consortium (IPDGC), International Genomics of Alzheimer's Project (IGAP), Parastoo Momeni, Gerard D Schellenberg, William P Dillon, Leo P Sugrue, Christopher P Hess, Jennifer S Yokoyama, Luke W Bonham, Gil D Rabinovici, Bruce L Miller, Ole A Andreassen, Anders M Dale, John Hardy, Rahul S Desikan
Feb 06, 2018
BACKGROUND: Clinical, pathological and genetic overlap between sporadic frontotemporal dementia (FTD), Alzheimer's disease (AD) and Parkinson's disease (PD) has been suggested; however, the relationship between these disorders...
Modifiable pathways in Alzheimer's disease
Susanna C Larsson, Matthew Traylor, Rainer Malik, Martin Dichgans, Stephen Burgess, Hugh S Markus, on behalf of the International Genomics of Alzheimer’s Project CoSTREAM Consortium
Mar 07, 2018
OBJECTIVE: To determine which potentially modifiable risk factors, including socioeconomic, lifestyle/dietary, cardiometabolic, and inflammatory factors, are associated with Alzheimer's disease. DESIGN: Mendelian randomisation...
W404-010J-01 - Office of the Vice President for Academic Affairs: Office of Sponsored Programs and Research (SPAR): Correspondence and Memoranda
Office of Vice President for Academic Affairs, Sponsored Programs and Research, Office of, Grants and Sponsored Research Development, Office of
Jan 01, 0001
Published by: Winthrop University
Pan-cancer analysis of whole genomes.
Cancer is driven by genetic change, and the advent of massively parallel sequencing has enabled systematic documentation of this variation at the whole-genome scale1-3. Here we report the integrative analysis of...
Cell Proliferation Cellular Senescence Chromothripsis Cloud Computing DNA Mutational Analysis evolution Molecular Female Genome Human Genomics Germ-Line Mutation High-Throughput Nucleotide Sequencing Humans Information Dissemination Male Mutagenesis Mutation Neoplasms Oncogenes Promoter Regions Genetic RNA Splicing Reproducibility of Results Telomerase Telomere
ImmUniverse Consortium
Stefania Vetrano, Gerben Bouma, Robert J Benschop, Thomas Birngruber, Antonio Costanzo, GRAM D'Haens, Loredana Frasca, Rainer Hillenbrand, Lars Iversen, Claus Johansen, Arthur Kaser, Hans JPM Koenen, Christa Noehammer, Laurent Peyrin-Biroulet, Jeroen Raes, Leonardo Ricotti, Philip Rosenstiel, Venkata P Satagopam, Stefan Schreiber, Severine Vermeire, Andreas Wollenberg, Stephan Weidinger, Daniel Ziemek, Silvio Danese, ImmUniverse Consortium
Jan 04, 2023
Immune mediated inflammatory diseases (IMIDs) are a heterogeneous group of debilitating, multifactorial and unrelated conditions featured by a dysregulated immune response leading to destructive chronic inflammation. The immune...
The Consortium of Metabolomics Studies (COMETS)
Bing Yu, Krista A Zanetti, Marinella Temprosa, Demetrius Albanes, Nathan Appel, Clara Barrios Barrera, Yoav Ben-Shlomo, Eric Boerwinkle, Juan P Casas, Clary Clish, Caroline Dale, Abbas Dehghan, Andriy Derkach, A Heather Eliassen, Paul Elliott, Eoin Fahy, Christian Gieger, Marc J Gunter, Sei Harada, Tamara Harris, Deron R Herr, David Herrington, Joel N Hirschhorn, Elise Hoover, Ann W Hsing, Mattias Johansson, Rachel S Kelly, Chin Meng Khoo, Mika Kivimäki, Bruce S Kristal, Claudia Langenberg, Jessica Lasky-Su, Deborah A Lawlor, Luca A Lotta, Massimo Mangino, Loïc Le Marchand, Ewy Mathé, Charles E Matthews, Cristina Menni, Lorelei A Mucci, Rachel Murphy, Matej Oresic, Eric Orwoll, Jennifer Ose, Alexandre C Pereira, Mary C Playdon, Lucilla Poston, Jackie Price, Qibin Qi, Kathryn Rexrode, Adam Risch, Joshua Sampson, Wei Jie Seow, Howard D Sesso, Svati H Shah, Xiao-Ou Shu, Gordon CS Smith, Ulla Sovio, Victoria L Stevens, Rachael Stolzenberg-Solomon, Toru Takebayashi, Therese Tillin, Ruth Travis, Ioanna Tzoulaki, Cornelia M Ulrich, Ramachandran S Vasan, Mukesh Verma, Ying Wang, Nick J Wareham, Andrew Wong, Naji Younes, Hua Zhao, Wei Zheng, Steven C Moore
Feb 11, 2019
Cancer cohort Diabetes Genetics Heart Disease Metabolomics Prospective Adolescent Adult Aged Aged 80 and over Biomarkers Body Mass Index Child Epidemiologic Methods EPIDEMIOLOGY Female Global Health Health Behavior Hematologic Tests Humans Longitudinal Studies Male Metabolomics Middle Aged Prospective Studies Socioeconomic Factors Young Adult
Expression Quantitative Trait Locus Mapping in Pulmonary Arterial Hypertension.
Anna Ulrich, Pablo Otero-Núñez, John Wharton, Emilia M Swietlik, Stefan Gräf, Nicholas W Morrell, Dennis Wang, Allan Lawrie, Martin R Wilkins, Inga Prokopenko, Christopher J Rhodes, On Behalf Of The Nihr BioResource-Rare Diseases Consortium, UK PAH Cohort Study Consortium
Jan 08, 2021
Expression quantitative trait loci (eQTL) can provide a link between disease susceptibility variants discovered by genetic association studies and biology. To date, eQTL mapping studies have been primarily conducted in healthy...
Blood eQTL expression quantitative trait locus Genetics pulmonary arterial hypertension Base Sequence Familial Primary Pulmonary Hypertension Female Genetic Association Studies Genetic Predisposition to Disease Genome Genome-Wide Association Study Humans Male Polymorphism Single Nucleotide pulmonary arterial hypertension Quantitative Trait Loci Sequence Analysis RNA Transcriptome
Expression Quantitative Trait Locus Mapping in Pulmonary Arterial Hypertension
Anna Ulrich, Pablo Otero-Núñez, John Wharton, Emilia M. Swietlik, Stefan Gräf, Nicholas W. Morrell, Dennis Wang, Allan Lawrie, Martin R. Wilkins, Inga Prokopenko, Christopher J. Rhodes, on behalf of The NIHR BioResource—Rare Diseases Consortium, UK PAH Cohort Study Consortium
Oct 23, 2020
Expression quantitative trait loci (eQTL) can provide a link between disease susceptibility variants discovered by genetic association studies and biology. To date, eQTL mapping studies have been primarily conducted in healthy...
Across-cohort QC analyses of GWAS summary statistics from complex traits.
Guo-Bo Chen, Sang Hong Lee, Matthew R Robinson, Maciej Trzaskowski, Zhi-Xiang Zhu, Thomas W Winkler, Felix R Day, Damien C Croteau-Chonka, Andrew R Wood, Adam E Locke, Zoltán Kutalik, Ruth JF Loos, Timothy M Frayling, Joel N Hirschhorn, Jian Yang, Naomi R Wray, Genetic Investigation of Anthropometric Traits (GIANT) Consortium, Peter M Visscher
Sep 05, 2018
Genome-wide association studies (GWASs) have been successful in discovering SNP trait associations for many quantitative traits and common diseases. Typically, the effect sizes of SNP alleles are very small and this requires...
Surveillance and Epidemiology of Drug Resistant Infections Consortium (SEDRIC)
Keiji Fukuda, Direk Limmathurotsakul, Iruka N Okeke, Nandini Shetty, Rogier van Doorn, Nicholas A Feasey, Francesca Chiara, Ghada Zoubiane, Tim Jinks, Julian Parkhill, Jean Patel, Stuart WJ Reid, Alison H Holmes, Sharon J Peacock, Surveillance and Epidemiology of Drug Resistant Infections Consortium (SEDRIC)
Nov 05, 2018
In recognition of the central importance of surveillance and epidemiology in the control of antimicrobial resistance and the need to strengthen surveillance at all levels, Wellcome has brought together a new international expert...
Rare variant analysis of 4241 pulmonary arterial hypertension cases from an international consortium implicates FBLN2, PDGFD, and rare de novo variants in PAH.
Na Zhu, Emilia M Swietlik, Carrie L Welch, Michael W Pauciulo, Jacob J Hagen, Xueya Zhou, Yicheng Guo, Johannes Karten, Divya Pandya, Tobias Tilly, Katie A Lutz, Jennifer M Martin, Carmen M Treacy, Erika B Rosenzweig, Usha Krishnan, Anna W Coleman, Claudia Gonzaga-Jauregui, Allan Lawrie, Richard C Trembath, Martin R Wilkins, Nicholas W Morrell, Yufeng Shen, Stefan Gräf, William C Nichols, Wendy K Chung
Jun 11, 2021
Background
Pulmonary arterial hypertension (PAH) is a lethal vasculopathy characterized by pathogenic remodeling of pulmonary arterioles leading to increased pulmonary pressures, right ventricular hypertrophy, and heart...
Genetics genome sequencing pulmonary arterial hypertension Exome Sequencing Case-control association testing De novo variant analysis
Published by: Genome medicine
Rare variant analysis of 4241 pulmonary arterial hypertension cases from an international consortium implicates FBLN2, PDGFD, and rare de novo variants in PAH
Na Zhu, Emilia M. Swietlik, Carrie L. Welch, Michael W. Pauciulo, Jacob J. Hagen, Xueya Zhou, Yicheng Guo, Johannes Karten, Divya Pandya, Tobias Tilly, Katie A. Lutz, Jennifer M. Martin, Carmen M. Treacy, Erika B. Rosenzweig, Usha Krishnan, Anna W. Coleman, Claudia Gonzaga-Juaregui, Allan Lawrie, Richard C. Trembath, Martin R. Wilkins, Nicholas W. Morrell, Yufeng Shen, Stefan Gräf, William C. Nichols, Wendy K. Chung, Russel Hirsch, R. James White, Marc Simon, David Badesch, Erika Rosenzweig, Charles Burger, Murali Chakinala, Thenappan Thenappan, Greg Elliott, Robert Simms, Harrison Farber, Robert Frantz, Jean Elwing, Nicholas Hill, Dunbar Ivy, James Klinger, Steven Nathan, Ronald Oudiz, Ivan Robbins, Robert Schilz, Terry Fortin, Jeffrey Wilt, Delphine Yung, Eric Austin, Ferhaan Ahmad, Nitin Bhatt, Tim Lahm, Adaani Frost, Zeenat Safdar, Zia Rehman, Robert Walter, Fernando Torres, Sahil Bakshi, Stephen Archer, Rahul Argula, Christopher Barnett, Raymond Benza, Ankit Desai, Veeranna Maddipati, Harm J. Bogaard, Colin Church, Gerry Coghlin, Robin Condliffe, Mélanie Eyries, Henning Gall, Stefano Ghio, Barbara Girerd, Simon Holden, Luke Howard, Marc Humbert, David G. Kiely, Gabor Kovacs, Jim Lordan, Rajiv D. Machado, Robert V. MacKenzie Ross, Colm McCabe, Shahin Moledina, David Montani, Horst Olschewski, Christopher J. Penkett, Joanna Pepke-Zaba, Laura Price, Christopher J. Rhodes, Werner Seeger, Florent Soubrier, Laura Southgate, Jay Suntharalingam, Andrew J. Swift, Mark R. Toshner, Anton Vonk Noordegraaf, John Wharton, Jim Wild, Stephen John Wort
May 10, 2021
Abstract: Background: Pulmonary arterial hypertension (PAH) is a lethal vasculopathy characterized by pathogenic remodeling of pulmonary arterioles leading to increased pulmonary pressures, right ventricular hypertrophy, and...
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