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A Two-Stage Robust Optimization for Reliable Logistics Network Design via Evolutionary Computation
This paper presents a novel two-stage robust optimization model for designing a dependable logistics network that integrates evolutionary computation techniques. The proposed model considers both the normal and disrupted states...
Published by: IGI Global Scientific Publishing
Information Seeking and Online Deal Seeking Behavior
Deal-seeking behavior is booming over the last decade. This article aims to identify online deal-seeking resources, understand the current status of online deal-seeking and identify key insights and trends for understanding...
Published by: IGI Global Scientific Publishing
Seven non-differentially expressed 'dark biomarkers' show transcriptional dysregulation in chronic lymphocytic leukemia.
Ruihao Xin, Xin Feng, Hang Zhang, Yueying Wang, Meiyu Duan, Tunyang Xie, Lin Dong, Qiong Yu, Lan Huang, Fengfeng Zhou
Jan 27, 2023
Aim: Transcriptional regulation is actively involved in the onset and progression of various diseases. This study used the feature-engineering approach model-based quantitative transcription regulation to quantitatively measure...
How the City of London lost at Brexit
HE Thompson
Aug 23, 2017
The nature of the City of London as an offshore financial centre has long made London dependent on the British state providing protection from external political regulation, even as London’s foreign currency business separated...
Diagnostics of Non-Maxwellian Electron Distributions in Solar Active Regions from Fe xii Lines Observed by the Hinode Extreme Ultraviolet Imaging Spectrometer and Interface Region Imaging Spectrograph
Abstract
We present joint Hinode Extreme Ultraviolet Imaging Spectrometer (EIS) and Interface Region Imaging Spectrograph (IRIS) observations of Fe xii lines in...
3, 4-dihydroxyl-phenyl lactic acid restores NADH dehydrogenase 1 α subunit 10 to ameliorate cardiac reperfusion injury.
Xiao-Yuan Yang, Ke He, Chun-Shui Pan, Quan Li, Yu-Ying Liu, Li Yan, Xiao-Hong Wei, Bai-He Hu, Xin Chang, Xiao-Wei Mao, Dan-Dan Huang, Li-Jun Wang, Shui-Wang Hu, Yong Jiang, Guo-Cheng Wang, Jing-Yu Fan, Tai-Ping Fan, Jing-Yan Han
Jan 10, 2018
The present study aimed to detect the role of 3, 4-dihydroxyl-phenyl lactic acid (DLA) during ischemia/reperfusion (I/R) induced myocardial injury with emphasis on the underlying mechanism of DLA antioxidant. Male Spragu-Dawley...
Animals Apoptosis Cardiotonic Agents Cell Line Disease Models Animal Electron Transport Complex I Gene Expression Lactic Acid Leukocytes Male Mitochondria Myocardial Infarction Myocardial Reperfusion Injury NADH Dehydrogenase Protein Binding Protein Subunits Rats Reactive Oxygen Species Sirtuin 1 Ventricular Function Left
A Novel Ensemble Learning Model Combined XGBoost With Deep Neural Network for Credit Scoring
Credit scoring, aiming to distinguish potential loan defaulter, has played an important role in the financial industry. To further improve the accuracy and efficiency of classification, this paper develops an ensemble model...
Published by: IGI Global Scientific Publishing
Inherent SM Voltage Balance for Multilevel Circulant Modulation in Modular Multilevel DC--DC Converters
Shiyuan Fan, Xin Xiang, Jing Sheng, Yunjie Gu, Huan Yang, Wuhua Li, Xiangning He, Timothy C Green
Feb 01, 2022
The modularity of a modular multilevel dc converter (MMDC) makes it attractive for medium-voltage distribution systems. Inherent balance of submodule (SM) capacitor voltages is considered as an ideal property, which avoids a...
Inherent SM Voltage Balance for Multilevel Circulant Modulation in Modular Multilevel DC--DC Converters
Shiyuan Fan, Xin Xiang, Jing Sheng, Yunjie Gu, Huan Yang, Wuhua Li, Xiangning He, Timothy C Green
Feb 01, 2022
The modularity of a modular multilevel dc converter (MMDC) makes it attractive for medium-voltage distribution systems. Inherent balance of submodule (SM) capacitor voltages is considered as an ideal property, which avoids a...
Implementing and Assessing a Teaching Mode Based on Smart Education in English Literature Teaching
This study addresses the problems in traditional English literature teaching methods for Chinese English majors, proposing a new teaching approach based on smart education concepts to enhance learning effectiveness. An...
Published by: IGI Global Scientific Publishing
Visible emission and energy transfer in Tb<sup>3+</sup>/Dy<sup>3+</sup> co-doped phosphate glasses
Yan Sun, Fei Yu, Meisong Liao, Juping Ma, Xin Wang, Dongbing He, Weiqing Gao, Jonathan Knight, Lili Hu
Dec 31, 2020
In this work, we systematically study the spectroscopic properties of Tb3+/Dy3+ co-doped phosphate glasses in the visible spectral region and explore the sensitization role of Dy3+ in the...
Electronic stopping power in gold
The electronic stopping power of H and He moving through gold is obtained to high accuracy using time-evolving density-functional theory, thereby bringing usual first principles accuracies into this kind of strongly coupled...
Visible emission and energy transfer in Tb<sup>3+</sup>/Dy<sup>3+</sup> co-doped phosphate glasses
Yan Sun, Fei Yu, Meisong Liao, Juping Ma, Xin Wang, Dongbing He, Weiqing Gao, Jonathan Knight, Lili Hu
Dec 31, 2020
In this work, we systematically study the spectroscopic properties of Tb3+/Dy3+ co-doped phosphate glasses in the visible spectral region and explore the sensitization role of Dy3+ in the...
Route to high-energy density polymeric nitrogen t-N via He-N compounds.
Yinwei Li, Xiaolei Feng, Hanyu Liu, Jian Hao, Simon AT Redfern, Weiwei Lei, Dan Liu, Yanming Ma
Mar 16, 2018
Polymeric nitrogen, stabilized by compressing pure molecular nitrogen, has yet to be recovered to ambient conditions, precluding its application as a high-energy density material. Here we suggest a route for synthesis of a...
Individual Decision Model for Using Technology of Health Crowdsensing in the Digital Era
Digital transformation has brought about great social changes, and individuals are constantly facing the challenge of using emerging technologies. This article, for the first time, combines the Diffusion of Innovation Theory and...
Published by: IGI Global Scientific Publishing
Leveraging User Ideas for Product Innovation in Open Innovation Communities
The abundance of user ideas in the open innovation community poses a challenge of information overload for enterprises, making it difficult to effectively adopt ideas for product innovation. Existing studies primarily focus on...
Published by: IGI Global Scientific Publishing
R-matrix Electron-impact Excitation Data for the H- and He-like Ions with Z = 6−30
Abstract
Plasma models built on extensive atomic data are essential to interpreting observed cosmic spectra. H-like Lyman series and He-like triplets observable in the X-ray band...
Fluorescent probes for the detection of disease-associated biomarkers
Wei Tao Dou, Hai Hao Han, Adam C. Sedgwick, Guo Biao Zhu, Yi Zang, Xin Rong Yang, Juyoung Yoon, Tony D. James, Jia Li, Xiao Peng He
Apr 30, 2022
Fluorescent probes have emerged as indispensable chemical tools to the field of chemical biology and medicine. The ability to detect intracellular species and monitor physiological processes has not only advanced our...
Metastasis-on-a-chip mimicking the progression of kidney cancer in the liver for predicting treatment efficacy.
Yimin Wang, Di Wu, Guohua Wu, Jianguo Wu, Siming Lu, James Lo, Yong He, Chao Zhao, Xin ZHAO, Hongbo Zhang, ShuQi Wang
Feb 06, 2020
Metastasis is one of the most important factors that lead to poor prognosis in cancer patients, and effective suppression of the growth of primary cancer cells in a metastatic site is paramount in averting cancer progression....
Chemotherapy Drug delivery. Metastasis-on-a-chip tumor progression Animals Antimetabolites Antineoplastic Cell Line Tumor Cell Survival Disease Progression Drug Screening Assays Antitumor Fluorouracil Hepatocytes Humans Kidney Neoplasms Liver Neoplasms Rats Rats Sprague-Dawley Treatment Outcome Tumor Microenvironment
Stokes drift through corals
We investigate the all-penetrating drift velocities, due to surface wave
motion in an effectively inviscid fluid that overlies a saturated porous bed of
finite depth. Previous work in this area either neglects the large-scale...
Fluorescent probes for the detection of disease-associated biomarkers
Wei Tao Dou, Hai Hao Han, Adam C. Sedgwick, Guo Biao Zhu, Yi Zang, Xin Rong Yang, Juyoung Yoon, Tony D. James, Jia Li, Xiao Peng He
Apr 30, 2022
Fluorescent probes have emerged as indispensable chemical tools to the field of chemical biology and medicine. The ability to detect intracellular species and monitor physiological processes has not only advanced our...
Evaluation of Reactivity of Monoclonal Antibodies Against Omp25 of Brucella spp.
Xin Yang, Zuoping He, Guoxia Zhang, Jinhui Lu, Hui Zhang, Hui Ren, Yanjun Tian, Heng Yang, Chuangfu Chen, Linhai Li, Yongshui Fu, Jean-Pierre Allain, Chengyao Li, Wenjing Wang
May 05, 2020
Brucellosis is a serious zoonosis occurring mainly in developing countries, and its diagnosis is largely dependent on serologic detection and bacterial culture. In this study, we developed the murine monoclonal antibodies (mAbs)...
Photochromic Fluorescent Probe Strategy for the Super-resolution Imaging of Biologically Important Biomarkers
Xianzhi Chai, Hai Hao Han, Adam C. Sedgwick, Na Li, Yi Zang, Tony D. James, Junji Zhang, Xi Le Hu, Yang Yu, Yao Li, Yan Wang, Jia Li, Xiao Peng He, He Tian
Oct 21, 2020
Here, we report a β-galactosidase (β-Gal)-responsive photochromic fluorescent probe, NpG, that was designed to prebind to human serum albumin (HSA) to form the probe/protein hybrid, NpG@HSA. The formation of NpG@HSA led to an...
Scale-out production of extracellular vesicles derived from natural killer cells via mechanical stimulation in a seesaw-motion bioreactor for cancer therapy.
Jianguo Wu, Di Wu, Guohua Wu, Ho-Pan Bei, Zihan Li, Han Xu, Yimin Wang, Dan Wu, Hui Liu, Shengyu Shi, Chao Zhao, Yibing Xu, Yong He, Jun Li, Changyong Wang, Xin ZHAO, ShuQi Wang
Aug 05, 2022
Extracellular vesicles (EVs) derived from immune cells have shown great anti-cancer therapeutic potential. However, inefficiency in EV generation has considerably impeded the development of EV-based basic research and clinical...
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