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Results: 17491
SCORE2-OP risk prediction algorithms
AIMS: The aim of this study was to derive and validate the SCORE2-Older Persons (SCORE2-OP) risk model to estimate 5- and 10-year risk of cardiovascular disease (CVD) in individuals aged over 70 years in four geographical risk...
Surveillance recommendations for DICER1 pathogenic variant carriers
Jette J Bakhuizen, Helen Hanson, Karin van der Tuin, Fiona Lalloo, Marc Tischkowitz, Karin Wadt, Marjolijn CJ Jongmans, SIOPE Host Genome Working Group, CanGene-CanVar Clinical Guideline Working Group, Expert Network Members
Oct 01, 2021
DICER1 syndrome is a rare genetic disorder that predisposes to a wide spectrum of tumors. Developing surveillance protocols for this syndrome is challenging because uncertainty exists about the clinical efficacy of surveillance...
Geographic and Sociodemographic Disparities in Cardiovascular Risk in Burkina Faso
Kadari Cisse, Sekou Samadoulougou, Mady Ouedraogo, Bruno Bonnechère, Jean-Marie Degryse, Seni Kouanda, Fati Kirakoya-Samadoulougou
Aug 15, 2021
BACKGROUND: Cardiovascular disease (CVD) risk assessment is a critical step in the current approach to the primary prevention of CVD, particularly in low-income countries such as Burkina Faso. In this study, we aimed to assess...
The GRAPPA-OMERACT Working Group
Ying Ying Leung, William Tillett, Ana-Maria Orbai, Alexis Ogdie, Lihi Eder, Laura C Coates, Richard Holland, Anna Antony, Niti Goel, Philip J Mease
Jun 30, 2020
The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA)-Outcome Measures in Rheumatology (OMERACT) Psoriatic Arthritis (PsA) working group provided updates at the 2019 GRAPPA annual meeting on its...
The GRAPPA-OMERACT Working Group
Ying Ying Leung, William Tillett, Ana-Maria Orbai, Alexis Ogdie, Lihi Eder, Laura C Coates, Richard Holland, Anna Antony, Niti Goel, Philip J Mease
Jun 30, 2020
The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA)-Outcome Measures in Rheumatology (OMERACT) Psoriatic Arthritis (PsA) working group provided updates at the 2019 GRAPPA annual meeting on its...
Estimating dose-response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality
BACKGROUND: Randomised trials of vitamin D supplementation for cardiovascular disease and all-cause mortality have generally reported null findings. However, generalisability of results to individuals with low vitamin D status...
Working for the future
Tochukwu Nweze, Mary Basil Nwoke, Juliet Ifeoma Nwufo, Richard Ikechukwu Aniekwu, Florian Lange
Jun 12, 2020
BACKGROUND: The dominant view based on the deficit model of developmental psychopathology is that early adverse rearing impairs cognition. In contrast, an emerging evolutionary-developmental model argues that individuals exposed...
Assessment of venous hemodynamics and volume homeostasis during pregnancy
Venous hemodynamics and volume homeostasis are important aspects of cardiovascular physiology. However, today their relevance is still very much underappreciated. Their most important role is maintenance and control of venous...
maternal hemodynamics plasma volume Pregnancy venous hemodynamics venous return volume homeostasis Blood Flow Velocity cardiac output Cardiovascular Physiological Phenomena Consensus Development Conferences as Topic Female Guidelines as Topic Hemodynamics Homeostasis Humans Maternal Health Pregnancy Pregnancy Complications Cardiovascular Prenatal Diagnosis Uterine Artery
Changing the name of diabetes insipidus
Working Group for Renaming Diabetes Insipidus, Hiroshi Arima, Timothy Cheetham, Mirjam Christ-Crain, Deborah Cooper, Mark Gurnell, Juliana B Drummond, Miles Levy, Ann I McCormack, Joseph Verbalis, John Newell-Price, John AH Wass
Nov 16, 2022
'What's in a name? That which we call a rose/By any other name would smell as sweet' (Juliet, from Romeo and Juliet by William Shakespeare). Shakespeare's implication is that a name is nothing but a word, and it therefore...
Information and Risk Modification Trial (INFORM)
Barbora Silarova, Joanne Lucas, Adam S Butterworth, Emanuele Di Angelantonio, Christine Girling, Kathryn Lawrence, Stuart Mackintosh, Carmel Moore, Rupert A Payne, Stephen J Sharp, Guy Shefer, Zoe Tolkien, Juliet Usher-Smith, Matthew Walker, John Danesh, Simon Griffin
Sep 29, 2016
Abstract
Background
Cardiovascular disease (CVD) remains the leading cause of death globally. Primary prevention of CVD requires cost-effective strategies to identify individuals at...
Developing Non-Laboratory Cardiovascular Risk Assessment Charts and Validating Laboratory and Non-Laboratory-Based Models.
Razieh Hassannejad, Marjan Mansourian, Hamidreza Marateb, Mohammad Reza Mohebian, Thomas Andrew Gaziano, Rodney T Jackson, Emanuele Di Angelantonio, Nizal Sarrafzadegan
Jan 06, 2022
BACKGROUND: Developing simplified risk assessment model based on non-laboratory risk factors that could determine cardiovascular risk as accurately as laboratory-based one can be valuable, particularly in developing countries...
Changes in waist circumference and risk of all-cause and CVD mortality
Angela A. Mulligan, Marleen A. H. Lentjes, Robert N. Luben, Nicholas J. Wareham, Kay-Tee Khaw
Oct 27, 2020
Abstract: Background: Measures of abdominal adiposity are strongly associated with all-cause mortality and cardiovascular disease (CVD). However, data are limited and conflicting regarding the consequences of changes in body fat...
Impact of socioeconomic deprivation on screening for cardiovascular disease risk in a primary prevention population
OBJECTIVES: Investigate the association between socioeconomic deprivation and completeness of cardiovascular disease (CVD) risk factor recording in primary care, uptake of screening in people with incomplete risk factor...
Review of the psoriatic arthritis working group at OMERACT 12
William Tillett, Lihi Eder, Niti Goel, Maarten de Wit, Alexis Ogdie, Ana Maria Orbai, Willemina Campbell, Oliver FitzGerald, Neil J. McHugh, Dafna D. Gladman, Vibeke Strand, Philip J. Mease
Jun 01, 2015
At the 2014 annual meeting of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA), the psoriatic arthritis (PsA) working group of OMERACT (Outcome Measures in Rheumatology) presented a review...
Ethnicity and prediction of cardiovascular disease
Therese Tillin, Alun D Hughes, Peter Whincup, Jamil Mayet, Naveed Sattar, Paul M McKeigue, Nish Chaturvedi, SABRE Study Group
Mar 21, 2018
OBJECTIVE: To evaluate QRISK2 and Framingham cardiovascular disease (CVD) risk scores in a tri-ethnic U.K. population. DESIGN: Cohort study. SETTING: West London. PARTICIPANTS: Randomly selected from primary care lists....
Predictive value for cardiovascular events of common carotid intima media thickness and its rate of change in individuals at high cardiovascular risk - Results from the PROG-IMT collaboration.
Matthias W Lorenz, Lu Gao, Kathrin Ziegelbauer, Giuseppe Danilo Norata, Jean Philippe Empana, Irene Schmidtmann, Hung-Ju Lin, Stela McLachlan, Lena Bokemark, Kimmo Ronkainen, Mauro Amato, Ulf Schminke, Sathanur R Srinivasan, Lars Lind, Shuhei Okazaki, Coen DA Stehouwer, Peter Willeit, Joseph F Polak, Helmuth Steinmetz, Dirk Sander, Holger Poppert, Moise Desvarieux, M Arfan Ikram, Stein Harald Johnsen, Daniel Staub, Cesare R Sirtori, Bernhard Iglseder, Oscar Beloqui, Gunnar Engström, Alfonso Friera, Francesco Rozza, Wuxiang Xie, Grace Parraga, Liliana Grigore, Matthieu Plichart, Stefan Blankenberg, Ta-Chen Su, Caroline Schmidt, Tomi-Pekka Tuomainen, Fabrizio Veglia, Henry Völzke, Giel Nijpels, Johann Willeit, Ralph L Sacco, Oscar H Franco, Heiko Uthoff, Bo Hedblad, Carmen Suarez, Raffaele Izzo, Dong Zhao, Thapat Wannarong, Alberico Catapano, Pierre Ducimetiere, Christine Espinola-Klein, Kuo-Liong Chien, Jackie F Price, Göran Bergström, Jussi Kauhanen, Elena Tremoli, Marcus Dörr, Gerald Berenson, Kazuo Kitagawa, Jacqueline M Dekker, Stefan Kiechl, Matthias Sitzer, Horst Bickel, Tatjana Rundek, Albert Hofman, Ellisiv B Mathiesen, Samuela Castelnuovo, Manuel F Landecho, Maria Rosvall, Rafael Gabriel, Nicola de Luca, Jing Liu, Damiano Baldassarre, Maryam Kavousi, Eric de Groot, Michiel L Bots, David N Yanez, Simon G Thompson, PROG-IMT Study Group
Jun 19, 2018
AIMS: Carotid intima media thickness (CIMT) predicts cardiovascular (CVD) events, but the predictive value of CIMT change is debated. We assessed the relation between CIMT change and events in individuals at high cardiovascular...
Review of the psoriatic arthritis working group at OMERACT 12
William Tillett, Lihi Eder, Niti Goel, Maarten de Wit, Alexis Ogdie, Ana Maria Orbai, Willemina Campbell, Oliver FitzGerald, Neil J. McHugh, Dafna D. Gladman, Vibeke Strand, Philip J. Mease
Jun 01, 2015
At the 2014 annual meeting of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA), the psoriatic arthritis (PsA) working group of OMERACT (Outcome Measures in Rheumatology) presented a review...
Whole grain intake compared with cereal fibre intake in association to CVD risk factors
Eden M Barrett, Birdem Amoutzopoulos, Marijka J Batterham, Sumantra Ray, Eleanor J Beck
Nov 12, 2020
OBJECTIVE: To investigate how intakes of whole grains and cereal fibre were associated to risk factors for CVD in UK adults. DESIGN: Cross-sectional analyses examined associations between whole grain and cereal fibre intakes and...
Sensitization in transplantation
Anat R Tambur, Patricia Campbell, Anita S Chong, Sandy Feng, Mandy L Ford, Howard Gebel, Ronald G Gill, Garnett Kelsoe, Vasilis Kosmoliaptsis, Roslyn B Mannon, Michael Mengel, Elaine F Reed, Nicole M Valenzuela, Chris Wiebe, I Esme Dijke, Harold C Sullivan, Peter Nickerson
Jan 07, 2021
The purpose of the STAR 2019 Working Group was to build on findings from the initial STAR report to further clarify the expectations, limitations, perceptions, and utility of alloimmune assays that are currently in use or in...
Equalization of four cardiovascular risk algorithms after systematic recalibration
Lisa Pennells, Stephen Kaptoge, Angela Wood, Mike Sweeting, Xiaohui Zhao, Ian White, Stephen Burgess, Peter Willeit, Thomas Bolton, Karel GM Moons, Yvonne T van der Schouw, Randi Selmer, Kay-Tee Khaw, Vilmundur Gudnason, Gerd Assmann, Philippe Amouyel, Veikko Salomaa, Mika Kivimaki, Børge G Nordestgaard, Michael J Blaha, Lewis H Kuller, Hermann Brenner, Richard F Gillum, Christa Meisinger, Ian Ford, Matthew W Knuiman, Annika Rosengren, Debbie A Lawlor, Henry Völzke, Cyrus Cooper, Alejandro Marín Ibañez, Edoardo Casiglia, Jussi Kauhanen, Jackie A Cooper, Beatriz Rodriguez, Johan Sundström, Elizabeth Barrett-Connor, Rachel Dankner, Paul J Nietert, Karina W Davidson, Robert B Wallace, Dan G Blazer, Cecilia Björkelund, Chiara Donfrancesco, Harlan M Krumholz, Aulikki Nissinen, Barry R Davis, Sean Coady, Peter H Whincup, Torben Jørgensen, Pierre Ducimetiere, Maurizio Trevisan, Gunnar Engström, Carlos J Crespo, Tom W Meade, Marjolein Visser, Daan Kromhout, Stefan Kiechl, Makoto Daimon, Jackie F Price, Agustin Gómez de la Cámara, J Wouter Jukema, Benoît Lamarche, Altan Onat, Leon A Simons, Maryam Kavousi, Yoav Ben-Shlomo, John Gallacher, Jacqueline M Dekker, Hisatomi Arima, Nawar Shara, Robert W Tipping, Ronan Roussel, Eric J Brunner, Wolfgang Koenig, Masaru Sakurai, Jelena Pavlovic, Ron T Gansevoort, Dorothea Nagel, Uri Goldbourt, Elizabeth LM Barr, Luigi Palmieri, Inger Njølstad, Shinichi Sato, WM Monique Verschuren, Cherian V Varghese, Ian Graham, Oyere Onuma, Philip Greenland, Mark Woodward, Majid Ezzati, Bruce M Psaty, Naveed Sattar, Rod Jackson, Paul M Ridker, Nancy R Cook, Ralph B D'Agostino, Simon G Thompson, John Danesh, Emanuele Di Angelantonio, Emerging Risk Factors Collaboration
Dec 11, 2018
AIMS: There is debate about the optimum algorithm for cardiovascular disease (CVD) risk estimation. We conducted head-to-head comparisons of four algorithms recommended by primary prevention guidelines, before and after...
Polygenic risk scores in cardiovascular risk prediction
Luanluan Sun, Lisa Pennells, Stephen Kaptoge, Christopher P. Nelson, Scott C. Ritchie, Gad Abraham, Matthew Arnold, Steven Bell, Thomas Bolton, Stephen Burgess, Frank Dudbridge, Qi Guo, Eleni Sofianopoulou, David Stevens, John R. Thompson, Adam S. Butterworth, Angela Wood, John Danesh, Nilesh J. Samani, Michael Inouye, Emanuele Di Angelantonio
Jan 14, 2021
Background: Polygenic risk scores (PRSs) can stratify populations into cardiovascular disease (CVD) risk groups. We aimed to quantify the potential advantage of adding information on PRSs to conventional risk factors in the...
Prospective evaluation of a breast-cancer risk model integrating classical risk factors and polygenic risk in 15 cohorts from six countries.
Amber N Hurson, Parichoy Pal Choudhury, Chi Gao, Anika Hüsing, Mikael Eriksson, Min Shi, Michael E Jones, D Gareth R Evans, Roger L Milne, Mia M Gaudet, Celine M Vachon, Daniel I Chasman, Douglas F Easton, Marjanka K Schmidt, Peter Kraft, Montserrat Garcia-Closas, Nilanjan Chatterjee, B-CAST Risk Modelling Group
Dec 15, 2020
BACKGROUND: Rigorous evaluation of the calibration and discrimination of breast-cancer risk-prediction models in prospective cohorts is critical for applications under clinical guidelines. We comprehensively evaluated an...
Sequential screening for lung cancer in a high-risk group: randomised controlled trial: LungSEARCH
Stephen G Spiro, Pallav L Shah, Robert C Rintoul, Jeremy George, Samuel Janes, Matthew Callister, Marco Novelli, Penny Shaw, Gabrijela Kocjan, Chris Griffiths, Mary Falzon, Richard Booton, Nicholas Magee, Michael Peake, Paul Dhillon, Kishore Sridharan, Andrew G Nicholson, Simon Padley, Magali N Taylor, Asia Ahmed, Jack Allen, Yenting Ngai, Nyasha Chinyanganya, Victoria Ashford-Turner, Sarah Lewis, Dahmane Oukrif, Pamela Rabbitts, Nicholas Counsell, Allan Hackshaw
Feb 08, 2021
BACKGROUND: Low-dose computed tomography (LDCT) screening detects early-stage lung cancer and reduces mortality. We proposed a sequential approach targeted to a high-risk group as a potentially efficient screening strategy....
Adenocarcinoma of Lung Bronchoscopy Carcinoma Large Cell Carcinoma Non-Small-Cell Lung Carcinoma Small Cell Carcinoma Squamous Cell Cytological Techniques Early Detection of Cancer Female Humans Lung Neoplasms Male Middle Aged Neoplasm Staging Optical Imaging Pulmonary Disease Chronic Obstructive Risk Assessment Sensitivity and Specificity Sputum Tomography X-Ray Computed United Kingdom
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