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Results: 415
Identifying dementia outcomes in UK Biobank
Tim Wilkinson, Christian Schnier, Kathryn Bush, Kristiina Rannikmäe, David E Henshall, Chris Lerpiniere, Naomi E Allen, Robin Flaig, Tom C Russ, Deborah Bathgate, Suvankar Pal, John T O'Brien, Cathie LM Sudlow, Dementias Platform UK and UK Biobank
Mar 06, 2019
Prospective, population-based studies that recruit participants in mid-life are valuable resources for dementia research. Follow-up in these studies is often through linkage to routinely-collected healthcare datasets. We...
Best practices for multi-ancestry, meta-analytic transcriptome-wide association studies
Arjun Bhattacharya, Jibril B Hirbo, Dan Zhou, Wei Zhou, Jie Zheng, Masahiro Kanai, Global Biobank Meta-analysis Initiative, Bogdan Pasaniuc, Eric R Gamazon, Nancy J Cox
Dec 08, 2022
The Global Biobank Meta-analysis Initiative (GBMI), through its diversity, provides a valuable opportunity to study population-wide and ancestry-specific genetic associations. However, with multiple ascertainment strategies and...
Impact of Premium and Price Cuts on Consumer Purchase Intention
This study aims to compare the price cut and premium promotion with study moderators are discount depth size, product type, premium characteristics, and country effect (Indonesia and Taiwan). The experiment was designed as...
Published by: IGI Global Scientific Publishing
Determinants of Consumption Behaviors of Korean Pop Culture in Taiwan
This paper presents a qualitative analysis of associations between intrinsic (e.g., functional), extrinsic (e.g., social) and cultural consumption values, and consumption behavior of Korean pop cultural contents (KPCC) in...
Published by: IGI Global Scientific Publishing
Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts.
Ying Wang, Shinichi Namba, Esteban Lopera, Sini Kerminen, Kristin Tsuo, Kristi Läll, Masahiro Kanai, Wei Zhou, Kuan-Han Wu, Marie-Julie Favé, Laxmi Bhatta, Philip Awadalla, Ben Brumpton, Patrick Deelen, Kristian Hveem, Valeria Lo Faro, Reedik Mägi, Yoshinori Murakami, Serena Sanna, Jordan W Smoller, Jasmina Uzunovic, Brooke N Wolford, Global Biobank Meta-analysis Initiative, Cristen Willer, Eric R Gamazon, Nancy J Cox, Ida Surakka, Yukinori Okada, Alicia R Martin, Jibril Hirbo
Mar 16, 2023
Polygenic risk scores (PRSs) have been widely explored in precision medicine. However, few studies have thoroughly investigated their best practices in global populations across different diseases. We here utilized data from...
Investigation of associations between retinal microvascular parameters and albuminuria in UK Biobank
Euan N Paterson, Chris Cardwell, Thomas J MacGillivray, Emanuele Trucco, Alexander S Doney, Paul Foster, Alexander P Maxwell, Gareth J McKay, UK Biobank Eye and Vision Consortium
May 10, 2021
BACKGROUND: Associations between microvascular variation and chronic kidney disease (CKD) have been reported previously. Non-invasive retinal fundus imaging enables evaluation of the microvascular network and may offer insight...
Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci.
Previous studies have suggested that naturally occurring genetic variation contributes to the risk of astigmatism. The purpose of this investigation was to identify genetic markers associated with corneal and refractive...
Astigmatism Biological Specimen Banks Cornea Corneal Diseases Female Genetic Predisposition to Disease Genome-Wide Association Study Guanine Nucleotide Exchange Factors Humans Male Middle Aged Myopia Nuclear Proteins Polymorphism Single Nucleotide Ubiquitin-Protein Ligases United Kingdom White People
Genetic map of regional sulcal morphology in the human brain from UK biobank data.
Benjamin B Sun, Stephanie J Loomis, Fabrizio Pizzagalli, Natalia Shatokhina, Jodie N Painter, Christopher N Foley, Biogen Biobank Team, Megan E Jensen, Donald G McLaren, Sai Spandana Chintapalli, Alyssa H Zhu, Daniel Dixon, Tasfiya Islam, Iyad Ba Gari, Heiko Runz, Sarah E Medland, Paul M Thompson, Neda Jahanshad, Christopher D Whelan
Oct 14, 2022
Genetic associations with macroscopic brain structure can provide insights into brain function and disease. However, specific associations with measures of local brain folding are largely under-explored. Here, we conducted...
Human Intestinal Parasites From the Wushantou Site in Neolithic Period Taiwan (800–1 BC)
Here, we investigate the presence of parasitic infections in Neolithic peoples from Taiwan to provide insight into the health and cultural development of these populations. Analysis was conducted on 27 soil samples collected...
Global Biobank Meta-analysis Initiative
Wei Zhou, Masahiro Kanai, Kuan-Han H Wu, Humaira Rasheed, Kristin Tsuo, Jibril B Hirbo, Ying Wang, Arjun Bhattacharya, Huiling Zhao, Shinichi Namba, Ida Surakka, Brooke N Wolford, Valeria Lo Faro, Esteban A Lopera-Maya, Kristi Läll, Marie-Julie Favé, Juulia J Partanen, Sinéad B Chapman, Juha Karjalainen, Mitja Kurki, Mutaamba Maasha, Ben M Brumpton, Sameer Chavan, Tzu-Ting Chen, Michelle Daya, Yi Ding, Yen-Chen A Feng, Lindsay A Guare, Christopher R Gignoux, Sarah E Graham, Whitney E Hornsby, Nathan Ingold, Said I Ismail, Ruth Johnson, Triin Laisk, Kuang Lin, Jun Lv, Iona Y Millwood, Sonia Moreno-Grau, Kisung Nam, Priit Palta, Anita Pandit, Michael H Preuss, Chadi Saad, Shefali Setia-Verma, Unnur Thorsteinsdottir, Jasmina Uzunovic, Anurag Verma, Matthew Zawistowski, Xue Zhong, Nahla Afifi, Kawthar M Al-Dabhani, Asma Al Thani, Yuki Bradford, Archie Campbell, Kristy Crooks, Geertruida H de Bock, Scott M Damrauer, Nicholas J Douville, Sarah Finer, Lars G Fritsche, Eleni Fthenou, Gilberto Gonzalez-Arroyo, Christopher J Griffiths, Yu Guo, Karen A Hunt, Alexander Ioannidis, Nomdo M Jansonius, Takahiro Konuma, Ming Ta Michael Lee, Arturo Lopez-Pineda, Yuta Matsuda, Riccardo E Marioni, Babak Moatamed, Marco A Nava-Aguilar, Kensuke Numakura, Snehal Patil, Nicholas Rafaels, Anne Richmond, Agustin Rojas-Muñoz, Jonathan A Shortt, Peter Straub, Ran Tao, Brett Vanderwerff, Manvi Vernekar, Yogasudha Veturi, Kathleen C Barnes, Marike Boezen, Zhengming Chen, Chia-Yen Chen, Judy Cho, George Davey Smith, Hilary K Finucane, Lude Franke, Eric R Gamazon, Andrea Ganna, Tom R Gaunt, Tian Ge, Hailiang Huang, Jennifer Huffman, Nicholas Katsanis, Jukka T Koskela, Clara Lajonchere, Matthew H Law, Liming Li, Cecilia M Lindgren, Ruth JF Loos, Stuart MacGregor, Koichi Matsuda, Catherine M Olsen, David J Porteous, Jordan A Shavit, Harold Snieder, Tomohiro Takano, Richard C Trembath, Judith M Vonk, David C Whiteman, Stephen J Wicks, Cisca Wijmenga, John Wright, Jie Zheng, Xiang Zhou, Philip Awadalla, Michael Boehnke, Carlos D Bustamante, Nancy J Cox, Segun Fatumo, Daniel H Geschwind, Caroline Hayward, Kristian Hveem, Eimear E Kenny, Seunggeun Lee, Yen-Feng Lin, Hamdi Mbarek, Reedik Mägi, Hilary C Martin, Sarah E Medland, Yukinori Okada, Aarno V Palotie, Bogdan Pasaniuc, Daniel J Rader, Marylyn D Ritchie, Serena Sanna, Jordan W Smoller, Kari Stefansson, David A van Heel, Robin G Walters, Sebastian Zöllner, Biobank of the Americas, Biobank Japan project, BioMe, BioVU, CanPath - Ontario Health Study, China Kadoorie Biobank Collaborative Group, Colorado Center for Personalized Medicine, deCODE Genetics, Estonian Biobank, FinnGen, Generation Scotland, Genes & Health Research Team, LifeLines, Mass General Brigham Biobank, Michigan Genomics Initiative, National Biobank of Korea, Penn Medicine BioBank, Qatar Biobank, QSkin Sun and Health Study, Taiwan Biobank, HUNT Study, UCLA ATLAS Community Health Initiative, Uganda Genome Resource, UK Biobank, Alicia R Martin, Cristen J Willer, Mark J Daly, Benjamin M Neale
Mar 16, 2023
Using UK Biobank for sexual minority health research
Aim: Despite poorer health and healthcare outcomes experienced by lesbian, gay and bisexual adults, data for research to characterize and address these disparities remain limited. Patients & methods: We describe sexual history...
Genetic map of regional sulcal morphology in the human brain from UK biobank data.
Benjamin B Sun, Stephanie J Loomis, Fabrizio Pizzagalli, Natalia Shatokhina, Jodie N Painter, Christopher N Foley, Biogen Biobank Team, Megan E Jensen, Donald G McLaren, Sai Spandana Chintapalli, Alyssa H Zhu, Daniel Dixon, Tasfiya Islam, Iyad Ba Gari, Heiko Runz, Sarah E Medland, Paul M Thompson, Neda Jahanshad, Christopher D Whelan
Nov 16, 2022
Genetic associations with macroscopic brain structure can provide insights into brain function and disease. However, specific associations with measures of local brain folding are largely under-explored. Here, we conducted...
Prevalence of dementia in mainland China, Hong Kong and Taiwan
Yu-Tzu Wu, Gemma-Claire Ali, Maëlenn Guerchet, A Matthew Prina, Kit Yee Chan, Martin Prince, Carol Brayne
Jun 20, 2018
BACKGROUND: There are several existing systematic reviews of prevalence of dementia for mainland China, Hong Kong and Taiwan, but several studies have been newly reported. The aim of this study is to update prevalence data in...
Discovery of Eurytrema Eggs in Sediment from a Colonial Period Latrine in Taiwan.
Hui-Yuan Yeh, Chieh-Fu Jeff Cheng, ChingJung Huang, Xiaoya Zhan, Weng Kin Wong, Piers D Mitchell
Feb 09, 2020
In this study we take a closer look at the diseases that afflicted Japanese police officers who were stationed in a remote mountainous region of Taiwan from 1921 to 1944. Samples were taken from the latrine at the Huabanuo...
Published by: The Korean journal of parasitology
Using UK Biobank for sexual minority health research
Aim: Despite poorer health and healthcare outcomes experienced by lesbian, gay and bisexual adults, data for research to characterize and address these disparities remain limited. Patients & methods: We describe sexual history...
Using UK Biobank for sexual minority health research.
Aim: Despite poorer health and healthcare outcomes experienced by lesbian, gay and bisexual adults, data for research to characterize and address these disparities remain limited. Patients & methods: We describe sexual history...
A Path Analysis of Online Group Buying
Online group buying has emerged as a new bargaining power for many shoppers and become more so as a result of increasingly growing popularity of social networking and community-based web sites. Aside from significant quantity...
Published by: IGI Global Scientific Publishing
Service Quality Dimensions in the Context of Herzberg Two Factor Theory
Prachi Aggarwal
Jan 01, 2023
The major objective of this paper is to develop a comprehensive set of determinants of service quality of organised grocery stores in context of countries with culturally distinct orientation and to further classify them as...
Published by: IGI Global Scientific Publishing
Comparison of risk factor associations in UK Biobank against representative, general population based studies with conventional response rates
Abstract: Objective: To compare established associations between risk factors and mortality in UK Biobank, a study with an exceptionally low rate of response to its baseline survey, against those from representative studies that...
Stronger Associations Between Sleep and Mental Health in Adults with Autism
This study examined sleep and its cognitive and affective correlates in adults with and without autism spectrum disorder (ASD), utilizing UK Biobank data. There were no group differences in subjective sleep duration [n = 220...
Quality control and removal of technical variation of NMR metabolic biomarker data in ~120,000 UK Biobank participants.
Scott C Ritchie, Praveen Surendran, Savita Karthikeyan, Samuel A Lambert, Thomas Bolton, Lisa Pennells, John Danesh, Emanuele Di Angelantonio, Adam S Butterworth, Michael Inouye
Mar 03, 2023
Metabolic biomarker data quantified by nuclear magnetic resonance (NMR) spectroscopy in approximately 121,000 UK Biobank participants has recently been released as a community resource, comprising absolute concentrations and...
Describing a new food group classification system for UK biobank
Carmen Piernas, Aurora Perez-Cornago, Min Gao, Heather Young, Zoe Pollard, Angela Mulligan, Marleen Lentjes, Jennifer Carter, Kathryn Bradbury, Tim J Key, Susan A Jebb
Nov 25, 2021
PURPOSE: The UK Biobank study collected detailed dietary data using a web-based self-administered 24 h assessment tool, the Oxford WebQ. We aimed to describe a comprehensive food grouping system for this questionnaire and to...
Rare variant contribution to human disease in 281,104 UK Biobank exomes.
Quanli Wang, Ryan S Dhindsa, Keren Carss, Andrew R Harper, Abhishek Nag, Ioanna Tachmazidou, Dimitrios Vitsios, Sri VV Deevi, Alex Mackay, Daniel Muthas, Michael Hühn, Susan Monkley, Henric Olsson, AstraZeneca Genomics Initiative, Sebastian Wasilewski, Katherine R Smith, Ruth March, Adam Platt, Carolina Haefliger, Slavé Petrovski
Oct 26, 2021
Genome-wide association studies have uncovered thousands of common variants associated with human disease, but the contribution of rare variants to common disease remains relatively unexplored. The UK Biobank contains detailed...
The Causal Effects of Health Conditions and Risk Factors on Social and Socioeconomic Outcomes
Sean Harrison, Alisha R Davies, Matt Dickson, Jessica Tyrrell, Michael J Green, Srinivasa Vittal Katikireddi, Desmond Campbell, Marcus Munafó, Padraig Dixon, Hayley E Jones, Frances Rice, Neil M Davies, Laura D Howe
Oct 31, 2020
Background
To estimate the causal effect of health conditions and risk factors on social and socioeconomic outcomes in UK Biobank. Evidence on socioeconomic impacts is important to understand because it can help governments...
To estimate the causal effect of health conditions and risk factors on social and socioeconomic outcomes in UK Biobank. Evidence on socioeconomic impacts is important to understand because it can help governments...
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