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Results: 100
Crystal structure of tripartite-type ABC transporter MacB from Acinetobacter baumannii.
Ui Okada, Eiki Yamashita, Arthur Neuberger, Mayu Morimoto, Hendrik W van Veen, Satoshi Murakami
Jan 24, 2018
The MacA-MacB-TolC tripartite complex is a transmembrane machine that spans both plasma membrane and outer membrane and actively extrudes substrates, including macrolide antibiotics, virulence factors, peptides and cell envelope...
ATP-Binding Cassette Transporters Acinetobacter baumannii Amino Acid Sequence Bacterial Proteins Conserved Sequence Crystallography X-Ray Drug Resistance Multiple Bacterial Escherichia coli Models Molecular Protein Domains Protein Structure Quaternary Recombinant Proteins Sequence Homology Amino Acid
Predicting and Visualizing Lateral Movements Based on ATT&CK and Quantification Theory Type 3
When a cyber incident occurs, organizations need to identify the attack's impacts. They have to investigate potentially infected devices as well as certainly infected devices. However, as an organization's network expands, it is...
Published by: IGI Global Scientific Publishing
Dissecting the Development and Function of C. elegans Glia with Mutations of the mls-2 and vab-3 Genes
Yoshimura Satoshi
Jan 01, 0001
The past decade has produced much evidence that glia, the major cellular component of vertebrate nervous systems, play active integral roles in a variety of processes including neuronal migration, synaptogenesis, and modulation...
Published by: Rockefeller University
RIKEN MetaDatabase
Recently, the number and heterogeneity of life science datasets published on the Web have increased significantly. However, biomedical scientists face numerous serious difficulties finding, using and publishing useful databases....
Published by: IGI Global Scientific Publishing
The evolutionally-conserved function of group B1 Sox family members confers the unique role of Sox2 in mouse ES cells.
Hitoshi Niwa, Akira Nakamura, Makoto Urata, Maki Shirae-Kurabayashi, Shigehiro Kuraku, Steven Russell, Satoshi Ohtsuka
Sep 29, 2016
BACKGROUND: In mouse ES cells, the function of Sox2 is essential for the maintenance of pluripotency. Since the Sox-family of transcription factors are well conserved in the animal kingdom, addressing the evolutionary origin of...
Flexible Multifunctional Sensors for Wearable and Robotic Applications
Mengying Xie, Kyohei Hisano, Mingzhu Zhu, Takuya Toyoshi, Min Pan, Shima Okada, Osamu Tsutsumi, Sadao Kawamura, Christopher Bowen
Mar 01, 2019
This review provides an overview of the current state-of-the-art of the emerging field of flexible multifunctional sensors for wearable and robotic applications. In these application sectors, there is a demand for high...
Flexible Multifunctional Sensors for Wearable and Robotic Applications
Mengying Xie, Kyohei Hisano, Mingzhu Zhu, Takuya Toyoshi, Min Pan, Shima Okada, Osamu Tsutsumi, Sadao Kawamura, Christopher Bowen
Mar 01, 2019
This review provides an overview of the current state-of-the-art of the emerging field of flexible multifunctional sensors for wearable and robotic applications. In these application sectors, there is a demand for high...
Design, Synthesis, and Chemical and Biological Properties of Cyclic ADP-4-Thioribose as a Stable Equivalent of Cyclic ADP-Ribose
T. Tsuzuki, S. Takano, N. Sakaguchi, T Kudoh, Takashi Murayama, Takashi Sakurai, Haruhiro Higashida, K Weber, A H Guse, T. Kameda, T. Hirokawa, Y. Kumaki, M Arisawa, Barry Potter, Satoshi Shuto
Jun 01, 2015
Here we describe the successful synthesis of cyclic ADP-4-thioribose (cADPtR, 3), designed as a stable mimic of cyclic ADP-ribose (cADPR, 1), a Ca2+-mobilizing second messenger, in which the key N1-β-thioribosyladenosine...
Detailed structural analysis of amorphous Pd<sub>40</sub>Cu<sub>40</sub>P<sub>20</sub>
Shinya Hosokawa, Jean François Bérar, Nathalie Boudet, Wolf Christian Pilgrim, László Pusztai, Satoshi Hiroi, Shinji Kohara, Hidemi Kato, Henry E. Fischer, Anita Zeidler
Mar 01, 2021
To clarify the relationship between the glass-forming ability (GFA) and local atomic structure of Pd-based metallic glasses, the structures of an amorphous Pd40Cu40P20 (PCP) were investigated...
Generation of Vascular Endothelial Cells and Hematopoietic Cells by Blastocyst Complementation.
Sanae Hamanaka, Ayumi Umino, Hideyuki Sato, Tomonari Hayama, Ayaka Yanagida, Naoaki Mizuno, Toshihiro Kobayashi, Mariko Kasai, Fabian Patrik Suchy, Satoshi Yamazaki, Hideki Masaki, Tomoyuki Yamaguchi, Hiromitsu Nakauchi
Dec 13, 2018
In the case of organ transplantation accompanied by vascular anastomosis, major histocompatibility complex mismatched vascular endothelial cells become a target for graft rejection. Production of a rejection-free, transplantable...
blastocyst complementation hematopoietic cells Pluripotent Stem Cells tissue regeneration vascular endothelial cells aging Animals Blastocyst Chimera Endothelial Cells Hematopoietic Stem Cells Induced Pluripotent Stem Cells Mice Inbred C57BL Mice Knockout Neovascularization Physiologic Pericytes Phenotype Platelet Endothelial Cell Adhesion Molecule-1 Vascular Endothelial Growth Factor Receptor-2
Microfluidics-based super-resolution microscopy enables nanoscopic characterization of blood stem cell rolling.
Karmen AbuZineh, Luay I Joudeh, Bader Al Alwan, Samir M Hamdan, Jasmeen S Merzaban, Satoshi Habuchi
Sep 20, 2018
Hematopoietic stem/progenitor cell (HSPC) homing occurs via cell adhesion mediated by spatiotemporally organized ligand-receptor interactions. Although molecules and biological processes involved in this multistep cellular...
Engineered MATE multidrug transporters reveal two functionally distinct ion-coupling pathways in NorM from Vibrio cholerae.
Sagar Raturi, Asha V Nair, Keiko Shinoda, Himansha Singh, Boyan Bai, Satoshi Murakami, Hideaki Fujitani, Hendrik W van Veen
Jun 12, 2021
Multidrug and toxic compound extrusion (MATE) transport proteins confer multidrug resistance on pathogenic microorganisms and affect pharmacokinetics in mammals. Our understanding of how MATE transporters work, has mostly relied...
Published by: Communications biology
Partial structure investigation of the traditional bulk metallic glass Pd40Ni40 P20
Shinya Hosokawa, Jean François Bérar, Nathalie Boudet, Wolf Christian Pilgrim, László Pusztai, Satoshi Hiroi, Kenji Maruyama, Shinji Kohara, Hidemi Kato, Henry E. Fischer, Anita Zeidler
Aug 28, 2019
Local structures of Pd40Ni40P20 bulk metallic glass were investigated by combining anomalous x-ray scattering close to the Pd and Ni K absorption edges, x-ray diffraction, neutron diffraction, and reverse Monte Carlo...
Relationship between atomic structure and excellent glass forming ability in Pd42.5Ni7.5Cu30P20 metallic glass
Shinya Hosokawa, Jean François Bérar, Nathalie Boudet, Wolf-Christian Pilgrim, László Pusztai, Satoshi Hiroi, Shinji Kohara, Hidemi Kato, Henry E. Fischer, Anita Zeidler
Nov 15, 2022
To understand the relation of the glass-forming ability (GFA) to the local atomic configurations of a
Pd42.5Ni7.5Cu30P20 (PNCP) metallic glass having the best GFA at present, the local structures were investigated...
Pd42.5Ni7.5Cu30P20 (PNCP) metallic glass having the best GFA at present, the local structures were investigated...
Synthesis and Properties of a Lead-Free Hybrid Double Perov-skite
Fengxia Wei, Zeyu Deng, Shijing Sun, Fenghua Zhang, Donald Evans, Gregor Kieslich, Satoshi Tominaka, Michael Carpenter, Jie Zhang, PD Bristowe, Anthony Cheetham
Mar 02, 2018
The discovery of lead-free hybrid double perovskites provides a viable approach in the search for stable and environmentally benign photovoltaic materials as alternatives to the lead-containing systems such as MAPbX3 (X = Cl...
Relationship between atomic structure and excellent glass forming ability in Pd42.5Ni7.5Cu30P20 metallic glass
Shinya Hosokawa, Jean François Bérar, Nathalie Boudet, Wolf-Christian Pilgrim, László Pusztai, Satoshi Hiroi, Shinji Kohara, Hidemi Kato, Henry E. Fischer, Anita Zeidler
Nov 15, 2022
To understand the relation of the glass-forming ability (GFA) to the local atomic configurations of a
Pd42.5Ni7.5Cu30P20 (PNCP) metallic glass having the best GFA at present, the local structures were investigated...
Pd42.5Ni7.5Cu30P20 (PNCP) metallic glass having the best GFA at present, the local structures were investigated...
Diet-Induced Obese Mice and Leptin-Deficient Lepob/ob Mice Exhibit Increased Circulating GIP Levels Produced by Different Mechanisms.
Eunyoung Lee, Emily L Miedzybrodzka, Xilin Zhang, Ryo Hatano, Junki Miyamoto, Ikuo Kimura, Kosuke Fujimoto, Satoshi Uematsu, Sergio Rodriguez-Cuenca, Antonio Vidal-Puig, Fiona M Gribble, Frank Reimann, Takashi Miki
Dec 11, 2019
As glucose-dependent insulinotropic polypeptide (GIP) possesses pro-adipogenic action, the suppression of the GIP hypersecretion seen in obesity might represent a novel therapeutic approach to the treatment of obesity. However...
diet-induced obese (DIO) mice Glucose-dependent insulinotropic polypeptide (GIP) High-fat diet interleukin-1 receptor antagonist (IL-1Ra) Leptin Animals Diet High-Fat Gastric Inhibitory Polypeptide Gene Expression Interleukin 1 Receptor Antagonist Protein Leptin Male Mice Inbred C57BL Mice Obese obesity Receptors G-Protein-Coupled Receptors Gastrointestinal Hormone
Partial structure investigation of the traditional bulk metallic glass Pd40Ni40 P20
Shinya Hosokawa, Jean François Bérar, Nathalie Boudet, Wolf Christian Pilgrim, László Pusztai, Satoshi Hiroi, Kenji Maruyama, Shinji Kohara, Hidemi Kato, Henry E. Fischer, Anita Zeidler
Aug 28, 2019
Local structures of Pd40Ni40P20 bulk metallic glass were investigated by combining anomalous x-ray scattering close to the Pd and Ni K absorption edges, x-ray diffraction, neutron diffraction, and reverse Monte Carlo...
Primary functional brain connections associated with melancholic major depressive disorder and modulation by antidepressants.
Naho Ichikawa, Giuseppe Lisi, Noriaki Yahata, Go Okada, Masahiro Takamura, Ryu-Ichiro Hashimoto, Takashi Yamada, Makiko Yamada, Tetsuya Suhara, Sho Moriguchi, Masaru Mimura, Yujiro Yoshihara, Hidehiko Takahashi, Kiyoto Kasai, Nobumasa Kato, Shigeto Yamawaki, Ben Seymour, Mitsuo Kawato, Jun Morimoto, Yasumasa Okamoto
Mar 27, 2020
The limited efficacy of available antidepressant therapies may be due to how they affect the underlying brain network. The purpose of this study was to develop a melancholic MDD biomarker to identify critically important...
Detailed structural analysis of amorphous Pd<sub>40</sub>Cu<sub>40</sub>P<sub>20</sub>
Shinya Hosokawa, Jean François Bérar, Nathalie Boudet, Wolf Christian Pilgrim, László Pusztai, Satoshi Hiroi, Shinji Kohara, Hidemi Kato, Henry E. Fischer, Anita Zeidler
Mar 01, 2021
To clarify the relationship between the glass-forming ability (GFA) and local atomic structure of Pd-based metallic glasses, the structures of an amorphous Pd40Cu40P20 (PCP) were investigated...
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