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Ancestral chromosomal signatures of Paenungulata (Afroteria) reveal the karyotype of Amazonian manatee (Trichechus inunguis, Sirenia
Flávia Dos Santos Tavares, Willam Oliveira da Silva, Malcolm Andrew Ferguson-Smith, Alex Garcia Cavalleiro de Macedo Klautau, Jairo Moura Oliveira, Angélica Lúcia Figueiredo Rodrigues, Gabriel Melo-Santos, Julio Cesar Pieczarka, Cleusa Yoshiko Nagamachi, Renata Coelho Rodrigues Noronha
Jan 24, 2023
BACKGROUND: Chromosomal painting in manatees has clarified questions about the rapid evolution of sirenians within the Paenungulata clade. Further cytogenetic studies in Afrotherian species may provide information about their...
Antikörpergerichtete Therapien
In its various forms, cancer remains a leading cause of mortality and morbidity worldwide. Thus, it is widely accepted that finding innovative, life-changing drugs and therapeutic regimens is key for successful future cancer...
Ecological and demographic correlates of cooperation from individual to budding dispersal
Identifying the ecological and demographic factors that promote the evolution of cooperation is a major challenge for evolutionary biologists. Explanations for the adaptive evolution of cooperation seek to determine which...
Integrating Digital Technologies in Accounting Preservice Teacher Education
Ana Rodrigues
Jan 01, 2022
The importance of developing technological skills at the undergraduate level to form better professionals is no longer questionable, assuming a particular role in subjects as accounting education. However, it appears that...
Published by: IGI Global Scientific Publishing
Machine learning for target discovery in drug development.
Chemical probes Chemical proteomics Drug Discovery Machine Learning target identification Antineoplastic Agents Computer Simulation Drug Evaluation Preclinical Humans lipoxygenase Machine Learning Molecular Targeted Therapy Naphthoquinones Pentacyclic Triterpenes Proteomics Receptors Cannabinoid Sesquiterpenes Sesquiterpenes Guaiane Transient Receptor Potential Channels
The bank of swimming organisms at the micron scale (BOSO-Micro)
Unicellular microscopic organisms living in aqueous environments outnumber all other creatures on Earth. A large proportion of them are able to self-propel in fluids with a vast diversity of swimming gaits and motility patterns....
Ecological and demographic correlates of cooperation from individual to budding dispersal
Identifying the ecological and demographic factors that promote the evolution of cooperation is a major challenge for evolutionary biologists. Explanations for the adaptive evolution of cooperation seek to determine which...
The social evolution of dispersal with public goods cooperation
Selection can favour the evolution of individually costly dispersal if this alleviates competition between relatives. However, conditions that favour altruistic dispersal also mediate selection for other social behaviours, such...
Circulating Tumor Cells
Circulating tumor cells (CTC) are the source of metastases, but only an infinitesimal fraction of them eventually succeed in colonizing a distant organ. New results show that CD44-dependent aggregation in the circulation...
Development of Antibody-Directed Therapies
Less is more: The efficacy of antibody-drug conjugates (ADCs) for cancer therapy is traditionally associated with cleavable linkers for payload release. Evidence now suggests that simpler constructs without cleavable moieties...
DynaMut
Proteins are highly dynamic molecules, whose function is intrinsically linked to their molecular motions. Despite the pivotal role of protein dynamics, their computational simulation cost has led to most structure-based...
Activation of CO 2 assimilation during photosynthetic induction is slower in C 4 than in C 3 photosynthesis in three phylogenetically controlled experiments
Lucía Arce Cubas, Richard L. Vath, Emmanuel L. Bernardo, Cristina Rodrigues Gabriel Sales, Angela C. Burnett, Johannes Kromdijk
Apr 11, 2023
Plant Science C4 photosynthesis C3 photosynthesis photosynthetic induction CO2 assimilation photorespiration non-steady state Light response
Published by: Frontiers Media S.A.
The social evolution of dispersal with public goods cooperation
Selection can favour the evolution of individually costly dispersal if this alleviates competition between relatives. However, conditions that favour altruistic dispersal also mediate selection for other social behaviours, such...
Impact of Brand Trust and Technology Readiness on the Willingness to Use Autonomous Cars in Brazil
This study sought to analyse whether brand trust and technology readiness influence the willingness to use (WTU) autonomous vehicles (AVs) in Brazil. A survey was applied with potential consumers, and the results, based on 213...
Published by: IGI Global Scientific Publishing
The bank of swimming organisms at the micron scale (BOSO-Micro).
Unicellular microscopic organisms living in aqueous environments outnumber all other creatures on Earth. A large proportion of them are able to self-propel in fluids with a vast diversity of swimming gaits and motility patterns....
Published by: PLOS ONE
Genomic control of metastasis
Abstract: Metastasis remains the leading cause of cancer-associated mortality, and a detailed understanding of the metastatic process could suggest new therapeutic avenues. However, how metastatic phenotypes arise at the genomic...
mCSM-PPI2
Benchmarking Binding Sites Crystallography X-Ray Datasets as Topic Humans Internet Machine Learning Mutation Missense Protein Binding Protein Conformation alpha-Helical Protein Conformation beta-Strand Protein Interaction Domains and Motifs Protein Interaction Mapping Proteins Software Thermodynamics
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