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Mapping the human genetic architecture of COVID-19.
COVID-19 Host Genetics Initiative
Jan 05, 2022
The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors have a role in the chance of exposure to SARS-CoV-2 and the severity of...
Autoimmunity Body Mass Index covid-19 Critical Illness Female Genetic Loci Genetic Predisposition to Disease Genome-Wide Association Study Geographic Mapping Hospitalization Host-Pathogen Interactions Humans Inflammation Information Dissemination Male Multifactorial Inheritance Racial Groups SARS-CoV-2 Smoking
Written Reminiscences of Dorothea Jansen
These written responses were completed by Dorothea Jansen as part of Project 2020: A Collaborative Oral History. These recollections provide insight into the COVID-19 pandemic and critical year 2020, notably from the perspective...
Published by: Winthrop University
Reminiscences of Biology 213-214
This collection of written reminiscences includes seven written accounts relating to the COVID-19 pandemic and 2020 experience, notably from the student perspective. Seven college students from a Winthrop Biology course...
Published by: Winthrop University
COVID-19 trajectories among 57 million adults in England
Johan H Thygesen, Christopher Tomlinson, Sam Hollings, Mehrdad A Mizani, Alex Handy, Ashley Akbari, Amitava Banerjee, Jennifer Cooper, Alvina G Lai, Kezhi Li, Bilal A Mateen, Naveed Sattar, Reecha Sofat, Ana Torralbo, Honghan Wu, Angela Wood, Jonathan AC Sterne, Christina Pagel, William N Whiteley, Cathie Sudlow, Harry Hemingway, Spiros Denaxas, Longitudinal Health and Wellbeing COVID-19 National Core Study and the CVD-COVID-UK/COVID-IMPACT Consortium
Jul 14, 2022
BACKGROUND: Updatable estimates of COVID-19 onset, progression, and trajectories underpin pandemic mitigation efforts. To identify and characterise disease trajectories, we aimed to define and validate ten COVID-19 phenotypes...
Pneumomediastinum in COVID-19
James Melhorn, Andrew Achaiah, Francesca M Conway, Elizabeth MF Thompson, Erik W Skyllberg, Joseph Durrant, Neda A Hasan, Yasser Madani, Prasheena Naran, Bavithra Vijayakumar, Matthew J Tate, Gareth E Trevelyan, Irfan Zaki, Catherine A Doig, Geraldine Lynch, Gill Warwick, Avinash Aujayeb, Karl A Jackson, Hina Iftikhar, Jonathan H Noble, Anthony YKC Ng, Mark Nugent, Philip J Evans, Robert A Hastings, Harry R Bellenberg, Hannah Lawrence, Rachel L Saville, Nikolas T Johl, Adam N Grey, Huw C Ellis, Cheng Chen, Thomas L Jones, Nadeem Maddekar, Shahul Leyakathali Khan, Ambreen Iqbal Muhammad, Hakim Ghani, Yadee Maung Maung Myint, Cecillia Rafique, Benjamin J Pippard, Benjamin RH Irving, Fawad Ali, Viola H Asimba, Aqeem Azam, Eleanor C Barton, Malvika Bhatnagar, Matthew P Blackburn, Kate J Millington, Nicholas J Budhram, Katherine L Bunclark, Toshit P Sapkal, Giles Dixon, Andrew JE Harries, Mohammad Ijaz, Vijayalakshmi Karunanithi, Samir Naik, Malik Aamaz Khan, Karishma Savlani, Vimal Kumar, Beatriz Lara Gallego, Noor A Mahdi, Caitlin Morgan, Neena Patel, Elen W Rowlands, Matthew S Steward, Richard S Thorley, Rebecca L Wollerton, Sana Ullah, David M Smith, Wojciech Lason, Anthony J Rostron, Najib M Rahman, Rob J Hallifax
Mar 14, 2022
BACKGROUND: There is an emerging understanding that coronavirus disease 2019 (COVID-19) is associated with increased incidence of pneumomediastinum. We aimed to determine its incidence among patients hospitalised with COVID-19...
The effect of human mobility and control measures on the COVID-19 epidemic in China.
Moritz UG Kraemer, Chia-Hung Yang, Bernardo Gutierrez, Chieh-Hsi Wu, Brennan Klein, David M Pigott, Open COVID-19 Data Working Group, Louis du Plessis, Nuno R Faria, Ruoran Li, William P Hanage, John S Brownstein, Maylis Layan, Alessandro Vespignani, Huaiyu Tian, Christopher Dye, Oliver G Pybus, Samuel V Scarpino
May 26, 2020
The ongoing coronavirus disease 2019 (COVID-19) outbreak expanded rapidly throughout China. Major behavioral, clinical, and state interventions were undertaken to mitigate the epidemic and prevent the persistence of the virus in...
Binary Classification of COVID-19 CT Images Using CNN
COVID-19 pandemic has hit the world with such a force that the world's leading economies are finding it challenging to come out of it. Countries with the best medical facilities are even cannot handle the increasing number of...
Published by: IGI Global Scientific Publishing
Importance of patient bed pathways and length of stay differences in predicting COVID-19 hospital bed occupancy in England.
Quentin J Leclerc, Naomi M Fuller, Ruth H Keogh, Karla Diaz-Ordaz, Richard Sekula, Malcolm G Semple, ISARIC4C investigators, CMMID COVID-19 working group, Katherine E Atkins, Simon R Procter, Gwenan M Knight
Aug 02, 2021
BACKGROUND: Predicting bed occupancy for hospitalised patients with COVID-19 requires understanding of length of stay (LoS) in particular bed types. LoS can vary depending on the patient's "bed pathway" - the sequence of...
The COVID-19 Data Portal
Peter W Harrison, Rodrigo Lopez, Nadim Rahman, Stefan Gutnick Allen, Raheela Aslam, Nicola Buso, Carla Cummins, Yasmin Fathy, Eloy Felix, Mihai Glont, Suran Jayathilaka, Sandeep Kadam, Manish Kumar, Katharina B Lauer, Geetika Malhotra, Abayomi Mosaku, Ossama Edbali, Young Mi Park, Andrew Parton, Matt Pearce, Jose Francisco Estrada Pena, Joseph Rossetto, Craig Russell, Sandeep Selvakumar, Xènia Pérez Sitjà, Alexey Sokolov, Ross Thorne, Marianna Ventouratou, Peter Walter, Galabina Yordanova, Amonida Zadissa, Guy Cochrane, Niklas Blomberg, Rolf Apweiler
Jul 29, 2021
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic will be remembered as one of the defining events of the 21st century. The rapid global outbreak has had significant impacts on human society and is...
Interview with Deitre Owens Helvy
This interview was conducted by Winthrop student Michaela Bessinger with Deitre Owens Helvy as part of Project 2020: A Collaborative Oral History. Helvy details her experiences as a Black female educator in Greenville County...
Covid-19 pandemic 2020 Education Virtual learning Greenville County School District social justice race
Published by: Winthrop University
An integrated national scale SARS-CoV-2 genomic surveillance network.
The Coronavirus Disease 2019 (COVID-19) Genomics UK Consortium (COG-UK) was launched in March, 2020, with £20 million support from UK Research and Innovation, the UK Department of Health and Social Care, and Wellcome Trust. The...
How Do People View COVID-19 Vaccines
The COVID-19 pandemic has been the most devastating public health crisis in the recent decade and vaccination is anticipated as the means to terminate the pandemic. People's views and feelings over COVID-19 vaccines determine...
Published by: IGI Global Scientific Publishing
Decreasing hospital burden of COVID-19 during the first wave in Regione Lombardia
Francesca Maria Grosso, Anne Margaret Presanis, Kevin Kunzmann, Chris Jackson, Alice Corbella, Giacomo Grasselli, Aida Andreassi, Annalisa Bodina, Maria Gramegna, Silvana Castaldi, Danilo Cereda, Daniela De Angelis, Covid-19 Lombardy Working Group
Jan 04, 2022
BACKGROUND: The aim of this study is to quantify the hospital burden of COVID-19 during the first wave and how it changed over calendar time; to interpret the results in light of the emergency measures introduced to manage the...
Coping with COVID-19
The COVID-19 pandemic might lead to more mental health problems. However, few studies have examined sleep problems, depression, and posttraumatic symptoms among the general adult population during the COVID-19 outbreak, and...
covid-19 Post-Traumatic Stress Symptoms (PTSS) Depression Insomnia Mental Health Adaptation Psychological Adolescent Adult Asian People Betacoronavirus covid-19 China Coronavirus Infections Depression Disease Outbreaks Female Humans Likelihood Functions Male Mental Health Middle Aged Pandemics Pneumonia Viral SARS-CoV-2 Sleep Wake Disorders Stress Disorders Post-Traumatic Surveys and Questionnaires Young Adult
Impact of COVID-19 pandemic on surgical neuro-oncology multi-disciplinary team decision making
Stephen John Price, Alexis Joannides, Puneet Plaha, Fardad Taghizadeh Afshari, Erminia Albanese, Neil U Barua, Huan Wee Chan, Giles Critchley, Thomas Flannery, Daniel M Fountain, Ryan K Mathew, Rory J Piper, Michael TC Poon, Chittoor Rajaraman, Ola Rominiyi, Stuart Smith, Georgios Solomou, Anna Solth, Surash Surash, Victoria Wykes, Colin Watts, Helen Bulbeck, Peter Hutchinson, Michael D Jenkinson, COVID-CNSMDT study group
Aug 17, 2020
OBJECTIVES: Pressures on healthcare systems due to COVID-19 has impacted patients without COVID-19 with surgery disproportionally affected. This study aims to understand the impact on the initial management of patients with...
Decreasing hospital burden of COVID-19 during the first wave in Regione Lombardia
Francesca Maria Grosso, Anne Presanis, Kevin Kunzmann, Chris Jackson, Alice Corbella, Giacomo Grasselli, Aida Andreassi, Annalisa Bodina, Maria Gramegna, Silvana Castaldi, Danilo Cereda, Daniela De Angelis, Covid-19 Lombardy Working Group
Sep 20, 2021
BACKGROUND: The aim of this study is to quantify the hospital burden of COVID-19 during the first wave and how it changed over calendar time; to interpret the results in light of the emergency measures introduced to manage the...
Task-Technology Fit and ICT Use in Remote Work Practice During the COVID-19 Pandemic
This study examines the use of information and communications technology (ICT) in remote work practice during the COVID-19 pandemic by integrating task-technology fit theory and the post-acceptance model of IS continuance into a...
Published by: IGI Global Scientific Publishing
Awareness and preparedness of healthcare workers against the first wave of the COVID-19 pandemic
Nguyen Tien Huy, R Matthew Chico, Vuong Thanh Huan, Hosam Waleed Shaikhkhalil, Vuong Ngoc Thao Uyen, Ahmad Taysir Atieh Qarawi, Shamael Thabit Mohammed Alhady, Nguyen Lam Vuong, Le Van Truong, Mai Ngoc Luu, Shyam Prakash Dumre, Atsuko Imoto, Peter N Lee, Dao Ngoc Hien Tam, Sze Jia Ng, Mohammad Rashidul Hashan, Mitsuaki Matsui, Nguyen Tran Minh Duc, Sedighe Karimzadeh, Nut Koonrungsesomboon, Chris Smith, Sharon Cox, Kazuhiko Moji, Kenji Hirayama, Le Khac Linh, Kirellos Said Abbas, Tran Nu Thuy Dung, Tareq Mohammed Ali Al-Ahdal, Emmanuel Oluwadare Balogun, Nguyen The Duy, Mennatullah Mohamed Eltaras, Trang Huynh, Nguyen Thi Linh Hue, Bui Diem Khue, Abdelrahman Gad, Gehad Mohamed Tawfik, Kazumi Kubota, Hoang-Minh Nguyen, Dmytro Pavlenko, Vu Thi Thu Trang, Le Thuong Vu, Tran Hai Yen, Nguyen Thi Yen-Xuan, Luong Thi Trang, Vinh Dong, Akash Sharma, Vu Quoc Dat, Mohammed Soliman, Jeza Abdul Aziz, Jaffer Shah, Pham Dinh Long Hung, Yap Siang Jee, Dang Thuy Ha Phuong, Tran Thuy Huong Quynh, Hoang Thi Nam Giang, Vy Thi Nhat Huynh, Nguyen Anh Thi, Nacir Dhouibi, Truc Phan, Vincent Duru, Nguyen Hai Nam, Sherief Ghozy, contributors of the TMGH-Global COVID-19 Collaborative, TMGH-Global COVID-19 Collaborative
Jan 28, 2022
BACKGROUND: Since the COVID-19 pandemic began, there have been concerns related to the preparedness of healthcare workers (HCWs). This study aimed to describe the level of awareness and preparedness of hospital HCWs at the time...
Clinical and organizational factors associated with mortality during the peak of first COVID-19 wave
Massimiliano Greco, Thomas De Corte, Ari Ercole, Massimo Antonelli, Elie Azoulay, Giuseppe Citerio, Andy Conway Morris, Gennaro De Pascale, Frantisek Duska, Paul Elbers, Sharon Einav, Lui Forni, Laura Galarza, Armand RJ Girbes, Giacomo Grasselli, Vitaly Gusarov, Alasdair Jubb, Jozef Kesecioglu, Andrea Lavinio, Maria Cruz Martin Delgado, Johannes Mellinghoff, Sheila Nainan Myatra, Marlies Ostermann, Mariangela Pellegrini, Pedro Povoa, Stefan J Schaller, Jean-Louis Teboul, Adrian Wong, Jan J De Waele, Maurizio Cecconi, ESICM UNITE-COVID investigators
Jul 07, 2022
PURPOSE: To accommodate the unprecedented number of critically ill patients with pneumonia caused by coronavirus disease 2019 (COVID-19) expansion of the capacity of intensive care unit (ICU) to clinical areas not previously...
Clinical and organizational factors associated with mortality during the peak of first COVID-19 wave
Massimiliano Greco, Thomas De Corte, Ari Ercole, Massimo Antonelli, Elie Azoulay, Giuseppe Citerio, Andy Conway Morris, Gennaro De Pascale, Frantisek Duska, Paul Elbers, Sharon Einav, Lui Forni, Laura Galarza, Armand RJ Girbes, Giacomo Grasselli, Vitaly Gusarov, Alasdair Jubb, Jozef Kesecioglu, Andrea Lavinio, Maria Cruz Martin Delgado, Johannes Mellinghoff, Sheila Nainan Myatra, Marlies Ostermann, Mariangela Pellegrini, Pedro Povoa, Stefan J Schaller, Jean-Louis Teboul, Adrian Wong, Jan J De Waele, Maurizio Cecconi, ESICM UNITE-COVID investigators
Jun 17, 2022
PURPOSE: To accommodate the unprecedented number of critically ill patients with pneumonia caused by coronavirus disease 2019 (COVID-19) expansion of the capacity of intensive care unit (ICU) to clinical areas not previously...
Exome-wide association study to identify rare variants influencing COVID-19 outcomes
Guillaume Butler-Laporte, Gundula Povysil, Jack A Kosmicki, Elizabeth T Cirulli, Theodore Drivas, Simone Furini, Chadi Saad, Axel Schmidt, Pawel Olszewski, Urszula Korotko, Mathieu Quinodoz, Elifnaz Çelik, Kousik Kundu, Klaudia Walter, Junghyun Jung, Amy D Stockwell, Laura G Sloofman, Daniel M Jordan, Ryan C Thompson, Diane Del Valle, Nicole Simons, Esther Cheng, Robert Sebra, Eric E Schadt, Seunghee Kim-schulze, Sacha Gnjatic, Miriam Merad, Joseph D Buxbaum, Noam D Beckmann, Alexander W Charney, Bartlomiej Przychodzen, Timothy Chang, Tess D Pottinger, Ning Shang, Fabian Brand, Francesca Fava, Francesca Mari, Karolina Chwialkowska, Magdalena Niemira, Szymon Pula, J Kenneth Baillie, Alex Stuckey, Antonio Salas, Xabier Bello, Jacobo Pardo-Seco, Alberto Gómez-Carballa, Irene Rivero-Calle, Federico Martinón-Torres, Andrea Ganna, Konrad J Karczewski, Kumar Veerapen, Mathieu Bourgey, Guillaume Bourque, Robert Jm Eveleigh, Vincenzo Forgetta, David Morrison, David Langlais, Mark Lathrop, Vincent Mooser, Tomoko Nakanishi, Robert Frithiof, Michael Hultström, Miklos Lipcsey, Yanara Marincevic-Zuniga, Jessica Nordlund, Kelly M Schiabor Barrett, William Lee, Alexandre Bolze, Simon White, Stephen Riffle, Francisco Tanudjaja, Efren Sandoval, Iva Neveux, Shaun Dabe, Nicolas Casadei, Susanne Motameny, Manal Alaamery, Salam Massadeh, Nora Aljawini, Mansour S Almutairi, Yaseen M Arabi, Saleh A Alqahtani, Fawz S Al Harthi, Amal Almutairi, Fatima Alqubaishi, Sarah Alotaibi, Albandari Binowayn, Ebtehal A Alsolm, Hadeel El Bardisy, Mohammad Fawzy, Fang Cai, Nicole Soranzo, Adam Butterworth, COVID-19 Host Genetics Initiative, DeCOI Host Genetics Group, GEN-COVID Multicenter Study (Italy), Mount Sinai Clinical Intelligence Center, GEN-COVID consortium (Spain), GenOMICC Consortium, Japan COVID-19 Task Force, Regeneron Genetics Center, Daniel H Geschwind, Stephanie Arteaga, Alexis Stephens, Manish J Butte, Paul C Boutros, Takafumi N Yamaguchi, Shu Tao, Stefan Eng, Timothy Sanders, Paul J Tung, Michael E Broudy, Yu Pan, Alfredo Gonzalez, Nikhil Chavan, Ruth Johnson, Bogdan Pasaniuc, Brian Yaspan, Sandra Smieszek, Carlo Rivolta, Stephanie Bibert, Pierre-Yves Bochud, Maciej Dabrowski, Pawel Zawadzki, Mateusz Sypniewski, Elżbieta Kaja, Pajaree Chariyavilaskul, Voraphoj Nilaratanakul, Nattiya Hirankarn, Vorasuk Shotelersuk, Monnat Pongpanich, Chureerat Phokaew, Wanna Chetruengchai, Katsushi Tokunaga, Masaya Sugiyama, Yosuke Kawai, Takanori Hasegawa, Tatsuhiko Naito, Ho Namkoong, Ryuya Edahiro, Akinori Kimura, Seishi Ogawa, Takanori Kanai, Koichi Fukunaga, Yukinori Okada, Seiya Imoto, Satoru Miyano, Serghei Mangul, Malak S Abedalthagafi, Hugo Zeberg, Joseph J Grzymski, Nicole L Washington, Stephan Ossowski, Kerstin U Ludwig, Eva C Schulte, Olaf Riess, Marcin Moniuszko, Miroslaw Kwasniewski, Hamdi Mbarek, Said I Ismail, Anurag Verma, David B Goldstein, Krzysztof Kiryluk, Alessandra Renieri, Manuel AR Ferreira, J Brent Richards
Dec 08, 2022
Host genetics is a key determinant of COVID-19 outcomes. Previously, the COVID-19 Host Genetics Initiative genome-wide association study used common variants to identify multiple loci associated with COVID-19 outcomes. However...
Dynamic interventions to control COVID-19 pandemic
Rajiv Chowdhury, Kevin Heng, Md Shajedur Rahman Shawon, Gabriel Goh, Daisy Okonofua, Carolina Ochoa-Rosales, Valentina Gonzalez-Jaramillo, Abbas Bhuiya, Daniel Reidpath, Shamini Prathapan, Sara Shahzad, Christian L Althaus, Nathalia Gonzalez-Jaramillo, Oscar H Franco, Global Dynamic Interventions Strategies for COVID-19 Collaborative Group
Aug 07, 2020
To date, non-pharmacological interventions (NPI) have been the mainstay for controlling the coronavirus disease-2019 (COVID-19) pandemic. While NPIs are effective in preventing health systems overload, these long-term measures...
Impact of COVID-19-related disruptions to measles, meningococcal A, and yellow fever vaccination in 10 countries.
Katy AM Gaythorpe, Kaja Abbas, John Huber, Andromachi Karachaliou, Niket Thakkar, Kim Woodruff, Xiang Li, Susy Echeverria-Londono, VIMC Working Group on COVID-19 Impact on Vaccine Preventable Disease, Matthew Ferrari, Michael L Jackson, Kevin McCarthy, T Alex Perkins, Caroline Trotter, Mark Jit
Sep 13, 2021
BACKGROUND: Childhood immunisation services have been disrupted by the COVID-19 pandemic. WHO recommends considering outbreak risk using epidemiological criteria when deciding whether to conduct preventive vaccination campaigns...
covid-19 EPIDEMIOLOGY Global Health human Mathematical modelling Measles Medicine Meningococcal disease Vaccination Yellow Fever Adolescent Adult Africa Bangladesh covid-19 Child Child Preschool Disease Outbreaks Humans Immunization Programs Infant Measles Measles Vaccine Meningococcal Infections Meningococcal Vaccines Pandemics Risk Assessment SARS-CoV-2 Vaccination Yellow Fever Yellow Fever Vaccine Young Adult
Impact of dexamethasone on SARS-CoV-2 concentration kinetics and antibody response in hospitalized COVID-19 patients
Barbara Mühlemann, Charlotte Thibeault, David Hillus, Elisa T Helbig, Lena J Lippert, Pinkus Tober-Lau, Tatjana Schwarz, Marcel A Müller, Pa-COVID-19 collaborative study group, Martin Witzenrath, Norbert Suttorp, Leif E Sander, Christian Drosten, Terry C Jones, Victor M Corman, Florian Kurth
Jul 28, 2021
OBJECTIVES: Dexamethasone has become the standard of care for severe coronavirus disease 2019 (COVID-19), but its virological impact is poorly understood. The objectives of this work were to characterize the kinetics of severe...
Antibody COVID-19 Nucleic Acid Testing Coronavirus disease 2019 (COVID-19) Dexamethasone Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Viral concentration Anti-Inflammatory Agents Antibodies Viral covid-19 Dexamethasone Hospitalization Humans Immunoglobulin A Immunoglobulin G Kinetics Prospective Studies RNA Viral Respiratory System SARS-CoV-2 Seroconversion Viral Load COVID-19 Drug Treatment
Quantification and reduction of cross-vendor variation in multicenter DWI MR imaging
Oliver Lukas Sedlaczek, Jens Kleesiek, Ferdia A Gallagher, Jacob Murray, Sebastian Prinz, Raquel Perez-Lopez, Evia Sala, Caroline Caramella, Sebastian Diffetock, Nathalie Lassau, Andrew N Priest, Chikako Suzuki, Roberto Vargas, Tommaso Giandini, Marta Vaiani, Antonella Messina, Lennart K Blomqvist, Regina GH Beets-Tan, Petra Oberrauch, Heinz-Peter Schlemmer, Michael Bach, CCE – Imaging Task Force
Nov 29, 2022
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