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Results: 308
Risks of breast or ovarian cancer in BRCA1 or BRCA2 predictive test negatives
Fabio Girardi, Daniel R Barnes, Daniel Barrowdale, Debra Frost, Angela F Brady, Claire Miller, Alex Henderson, Alan Donaldson, Alex Murray, Carole Brewer, Caroline Pottinger, D Gareth Evans, Diana Eccles, EMBRACE, Fiona Lalloo, Helen Gregory, Jackie Cook, Jacqueline Eason, Julian Adlard, Julian Barwell, Kai Ren Ong, Lisa Walker, Louise Izatt, Lucy E Side, M John Kennedy, Marc Tischkowitz, Mark T Rogers, Mary E Porteous, Patrick J Morrison, Ros Eeles, Rosemarie Davidson, Katie Snape, Douglas F Easton, Antonis C Antoniou
Mar 16, 2018
PURPOSE: BRCA1/BRCA2 predictive test negatives are proven noncarriers of a BRCA1/BRCA2 mutation that is carried by their relatives. The risk of developing breast cancer (BC) or epithelial ovarian cancer (EOC) in these women is...
Embrace Uncertainty
Consumers' worse-than-expected disconfirmation in ecommerce settings leads to several negative consequences, such as product returns and sales reductions. In contrast to common remedy strategies, a novel, proactive strategy...
Published by: IGI Global Scientific Publishing
The androgen receptor CAG repeat polymorphism and modification of breast cancer risk in BRCA1 and BRCA2 mutation carriers.
Amanda B Spurdle, Antonis C Antoniou, David L Duffy, Nirmala Pandeya, Livia Kelemen, Xiaoqing Chen, Susan Peock, Margaret R Cook, Paula L Smith, David M Purdie, Beth Newman, Gillian S Dite, Carmel Apicella, Melissa C Southey, Graham G Giles, John L Hopper, Georgia Chenevix-Trench, Douglas F Easton, EMBRACE Study Collaborators
Jun 17, 2011
INTRODUCTION: The androgen receptor (AR) gene exon 1 CAG repeat polymorphism encodes a string of 9-32 glutamines. Women with germline BRCA1 mutations who carry at least one AR allele with 28 or more repeats have been reported to...
Self‐Lowering as Power and Trap
Rupert Stasch
Jun 24, 2021
ABSTRACT: Building on Ferguson's account of ‘declarations of dependence’ and prior Melanesianist work on ‘humiliation’, I examine how enthusiasm for state‐formation among Korowai of Papua has been shaped by their understandings...
Use of multidimensional item response theory methods for dementia prevalence prediction
GBD 2019 Dementia Collaborators
Oct 11, 2021
BACKGROUND: Data sparsity is a major limitation to estimating national and global dementia burden. Surveys with full diagnostic evaluations of dementia prevalence are prohibitively resource-intensive in many settings. However...
How Do CIOs Become CEOs?
The role of information systems and technologies in any modern organization has become increasingly important. Concepts such as digital transformation and disruptive technologies have become the strategic directions for new and...
Published by: IGI Global Scientific Publishing
Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970-2016
GBD 2016 Mortality Collaborators
Oct 03, 2018
BACKGROUND: Detailed assessments of mortality patterns, particularly age-specific mortality, represent a crucial input that enables health systems to target interventions to specific populations. Understanding how all-cause...
Adolescent Adult Age Distribution Aged Aged 80 and over Birth Rate Cause of Death Child Child Preschool Educational Status Female Global Burden of Disease Global Health HIV Infections Humans Infant Infant Newborn Life Expectancy Male Middle Aged Socioeconomic Factors Stillbirth Survival Rate Young Adult
Global, regional, and national burden of Alzheimer's disease and other dementias, 1990-2016
GBD 2016 Dementia Collaborators
Feb 08, 2019
BACKGROUND: The number of individuals living with dementia is increasing, negatively affecting families, communities, and health-care systems around the world. A successful response to these challenges requires an accurate...
Making a Musical: The Art of Adapting a Film or a Book for the Stage
David Wohl
Jan 01, 0001
Over the past 100 years, stage musicals have been made from original works as varied as straight plays, novels, magazine articles, movies, short stories, poems, and biographies. This article explores two original works (a film...
Theatre Musical Adaptation film novel Arts and Humanities Playwriting Theatre and Performance Studies
Published by: Winthrop University
Measuring the health-related Sustainable Development Goals in 188 countries
GBD 2015 SDG Collaborators
Nov 21, 2017
BACKGROUND: In September, 2015, the UN General Assembly established the Sustainable Development Goals (SDGs). The SDGs specify 17 universal goals, 169 targets, and 230 indicators leading up to 2030. We provide an analysis of 33...
Global, regional, national, and selected subnational levels of stillbirths, neonatal, infant, and under-5 mortality, 1980-2015
GBD 2015 Child Mortality Collaborators
Nov 30, 2017
BACKGROUND: Established in 2000, Millennium Development Goal 4 (MDG4) catalysed extraordinary political, financial, and social commitments to reduce under-5 mortality by two-thirds between 1990 and 2015. At the country level...
Global, regional, and national burden of neurological disorders, 1990-2016
GBD 2016 Neurology Collaborators
Sep 18, 2019
BACKGROUND: Neurological disorders are increasingly recognised as major causes of death and disability worldwide. The aim of this analysis from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 is to...
Global, regional, and national levels of maternal mortality, 1990-2015
GBD 2015 Maternal Mortality Collaborators
Nov 30, 2017
BACKGROUND: In transitioning from the Millennium Development Goal to the Sustainable Development Goal era, it is imperative to comprehensively assess progress toward reducing maternal mortality to identify areas of success...
Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990-2017
GBD 2017 Risk Factor Collaborators
Sep 18, 2019
BACKGROUND: The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 comparative risk assessment (CRA) is a comprehensive approach to risk factor quantification that offers a useful tool for synthesising...
Adolescent Adult Age Distribution Aged Aged 80 and over Child Child Preschool Disabled Persons Environmental Exposure Female Global Burden of Disease Global Health Health Risk Behaviors Humans Infant Infant Newborn Life Expectancy Male Metabolic Diseases Middle Aged Occupational Diseases occupational exposure Quality-Adjusted Life Years Risk Assessment Sex Distribution Socioeconomic Factors Young Adult
Viewing the Ediacaran biota as a failed experiment is unhelpful.
Macroscopic organisms from the late Ediacaran period have often been described as failed experiments in the history of life. We argue that the field of Ediacaran palaeobiology should dispense with unhelpful historical...
The Grizzly, November 6, 2014
Rachel Brown, Deana Harley, Phoebe French, Dysean Alexander, Brian Thomas, Maxwell Bicking, Aliki Torrence, Christopher Santoro, Jaime Bocanumenth, Rayleen Rivera-Harbach, Gerard Brown, Drae Lewis, Olivia Frymark
Jan 01, 0001
Dr. Peter Small Appointed as Interim Dean Berman Receives Large Grant Graduates Granted Campus Housing Campus Safety Handles Thefts Senate Changes Organization Learning to Embrace American Foods Watson Fellowship Nominees...
Ursinus College Collegeville Pennsylvania newspaper Peter Small Berman Art Museum campus safety student housing student government Wismer dining hall Thomas J. Watson Foundation Myrin Library Jennifer Fleeger Swimming wrestling field hockey cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
The Grizzly, August 28, 2008
Kristin O'Brassill, Gabrielle Poretta, Kristi Blust, Barbara von Schlegell, Roger Lee, Christopher Schaeffer, Zach Shamberg, Katie Callahan, Stephanie Weir
Jan 01, 0001
Ursinus Welcomes Class of 2012: Largest in History Students Embrace Unique Summer Research Opportunity Academic Insight into the Lighter Side of Ramadan That Dream Internship Just Might be Within Your Reach Berman...
Ursinus College Collegeville Pennsylvania newspaper enrollment summer fellows career planning Berman Art Museum Wismer dining hall theater dance cross country cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2017
GBD 2017 DALYs and HALE Collaborators
Feb 08, 2019
BACKGROUND: How long one lives, how many years of life are spent in good and poor health, and how the population's state of health and leading causes of disability change over time all have implications for policy, planning, and...
What Factors Determine Treatment Outcome in Aneurysmal Subarachnoid Hemorrhage in the Modern Era? A Post Hoc STASH Analysis.
BACKGROUND: The management of aneurysmal subarachnoid hemorrhage (aSAH) has changed dramatically in the last few decades with the publication of a few major studies, including ISAT (International Subarachnoid Aneurysm Trial, the...
Endovascular coiling Neurosurgical clipping Post hoc analysis Propensity matched analysis aSAH Adolescent Adult Age Factors Aged Angiography Digital Subtraction Anticholesteremic Agents Endovascular Procedures Female Humans International Cooperation Intracranial Aneurysm Male Middle Aged Outcome Assessment Health Care Regression Analysis Risk Factors Simvastatin Subarachnoid Hemorrhage Tomography Scanners X-Ray Computed Treatment Outcome Young Adult
The global burden of typhoid and paratyphoid fevers
GBD 2017 Typhoid and Paratyphoid Collaborators
Apr 18, 2019
BACKGROUND: Efforts to quantify the global burden of enteric fever are valuable for understanding the health lost and the large-scale spatial distribution of the disease. We present the estimates of typhoid and paratyphoid fever...
Adolescent Adult Aged Aged 80 and over Cause of Death Child Child Preschool Disabled Persons Female Global Burden of Disease Humans Incidence Infant Life Expectancy Male Mass Vaccination Middle Aged Paratyphoid Fever Quality-Adjusted Life Years Risk Factors Salmonella enterica Sanitation Typhoid Fever Typhoid-Paratyphoid Vaccines Young Adult
Multicentre evaluation of renal impairment in thoracic surgery (MERITS)
Vinci Naruka, Mikel Alexander McKie, Navid Ahmadi, EA Claudia Pama, Aman S Coonar, Merits Collaborators
Oct 29, 2022
OBJECTIVES: To measure the unit-level variation in Acute Kidney Injury (AKI) incidence post-thoracic surgery over a contemporary 1-year period. Secondary aims include examining the associations with sex, age group, operation...
Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories
GBD 2017 SDG Collaborators
Sep 18, 2019
BACKGROUND: Efforts to establish the 2015 baseline and monitor early implementation of the UN Sustainable Development Goals (SDGs) highlight both great potential for and threats to improving health by 2030. To fully deliver on...
Essential Emergency and Critical Care
Carl Otto Schell, Karima Khalid, Alexandra Wharton-Smith, Jacquie Oliwa, Hendry R Sawe, Nobhojit Roy, Alex Sanga, John C Marshall, Jamie Rylance, Claudia Hanson, Raphael K Kayambankadzanja, Lee A Wallis, Maria Jirwe, Tim Baker, EECC Collaborators, EECC Collaborators*
Oct 19, 2021
BACKGROUND: Globally, critical illness results in millions of deaths every year. Although many of these deaths are potentially preventable, the basic, life-saving care of critically ill patients are often overlooked in health...
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