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Results: 6265
Understanding the influences on successful quality improvement in emergency general surgery
Timothy J Stephens, Jonathan R Bamber, Ian J Beckingham, Ellie Duncan, Nial F Quiney, John F Abercrombie, Graham Martin, Chole-QuIC collaborator group
May 13, 2019
BACKGROUND: Acute gallstone disease is the highest volume Emergency General Surgical presentation in the UK. Recent data indicate wide variations in the quality of care provided across the country, with national guidance for...
Breakthrough collaborative evaluation Gallstone disease Normalisation process theory Quality Improvement service improvement Acute Disease Attitude of Health Personnel Case-Control Studies Cholecystectomy Cooperative Behavior Emergency Service hospital Gallstones Humans leadership Patient Care Team Prospective Studies Quality Improvement Time-to-Treatment United Kingdom
Understanding the influences on successful quality improvement in emergency general surgery
Timothy J. Stephens, Jonathan R. Bamber, Ian J. Beckingham, Ellie Duncan, Nial F. Quiney, John F. Abercrombie, Graham Martin, Jenny Abraham, Jawad Ahmad, Ibrahim Ahmed, Melanie Andrews, Barry Appleton, Mohammad Asif, Russell Bolton, Christopher Briggs, Uchihara Bumagat, Simon Burchfield, Gemma Cochrane, Ffion Dewi, George Dovell, Sarah Dyer, Jemma Edge, Rachel Edwards, Ismay Fabre, Elizabeth Gemmill, Ewen Griffiths, Deepak Hariharan, Emma Harrington-Patel, Ahmed Hassn, Michael Hepworth, James Hewes, Sarah Hine, Marianne Hollyman, Kelly Ide, Deborah Jenner, Richard Johnson, Simon Jordan, Stavros Karamanakos, Joshua Kovoor, Neil Kukreja, Gabriele Marangoni, Nicola Metcalfe, Paul Morcous, Paul Needham, Niv Patel, Nabeel Qureshi, Niroshini Rajaretnam, Ilayaraja Rajendran, Yousuf Sabah, David L. Sanders, Andrew Sandison, Jennifer Sansom, Rashmi Seth, Vinutha Shetty, Tomas Sollei, Sean Strong, Laura Sullivan, Robert P. Sutcliffe, Lee Talbot, Gillian Taylor, Viju Varadarajan, Edward Villatoro, Judith Wardale, Simon Weaver, Tom Wiggins, Alexander Wood
Aug 24, 2020
Abstract: Background: Acute gallstone disease is the highest volume Emergency General Surgical presentation in the UK. Recent data indicate wide variations in the quality of care provided across the country, with national...
Effectiveness of a quality improvement collaborative in reducing time to surgery for patients requiring emergency cholecystectomy.
J R Bamber, T J Stephens, D A Cromwell, E Duncan, G P Martin, N F Quiney, J F Abercrombie, I J Beckingham
Jan 12, 2020
Background:Acute gallstone disease is a high-volume emergency general surgery presentation with wide variations in the quality of care provided across the UK. This controlled cohort evaluation assessed whether participation in a...
Effectiveness of a quality improvement collaborative in reducing time to surgery for patients requiring emergency cholecystectomy.
JR Bamber, TJ Stephens, DA Cromwell, E Duncan, GP Martin, NF Quiney, JF Abercrombie, IJ Beckingham, Cholecystectomy Quality Improvement Collaborative
Oct 11, 2019
BACKGROUND: Acute gallstone disease is a high-volume emergency general surgery presentation with wide variations in the quality of care provided across the UK. This controlled cohort evaluation assessed whether participation in...
Global, regional, and national burden of neurological disorders during 1990-2015
GBD 2015 Neurological Disorders Collaborator Group
Jan 31, 2019
BACKGROUND: Comparable data on the global and country-specific burden of neurological disorders and their trends are crucial for health-care planning and resource allocation. The Global Burden of Diseases, Injuries, and Risk...
The Max-Min Group Contest
We investigate a group all-pay auction in which each group's effort is represented by the minimum among the effort levels exerted by the group members and the prize is a group-specific public good. We fully characterize the...
The Max-Min Group Contest
We investigate a group all-pay auction in which each group's effort is represented by the minimum among the effort levels exerted by the group members and the prize is a group-specific public good. We fully characterize the...
Cross-phenotype analysis of Immunochip data identifies KDM4C as a relevant locus for the development of systemic vasculitis.
Lourdes Ortiz-Fernández, Francisco David Carmona, Raquel López-Mejías, Maria Francisca González-Escribano, Paul A Lyons, Ann W Morgan, Amr H Sawalha, Peter A Merkel, Kenneth GC Smith, Miguel A González-Gay, Javier Martín, UK GCA Consortium, Turkish Takayasu Study Group, Vasculitis Clinical Research Consortium, IgAV Study Group, AAV Study group Spanish GCA Study Group
Apr 18, 2018
OBJETIVE: Systemic vasculitides represent a heterogeneous group of rare complex diseases of the blood vessels with a poorly understood aetiology. To investigate the shared genetic component underlying their predisposition, we...
Autoantibodies outcomes research systemic sclerosis Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis Case-Control Studies Epigenesis Genetic Female Genetic Loci Genetic Predisposition to Disease Giant Cell Arteritis HLA-DQ Antigens HLA-DQ beta-Chains Humans Jumonji Domain-Containing Histone Demethylases Linkage Disequilibrium Male Phenotype Polymorphism Single Nucleotide Protein Array Analysis Systemic Vasculitis Takayasu arteritis
Surveillance recommendations for DICER1 pathogenic variant carriers
Jette J Bakhuizen, Helen Hanson, Karin van der Tuin, Fiona Lalloo, Marc Tischkowitz, Karin Wadt, Marjolijn CJ Jongmans, SIOPE Host Genome Working Group, CanGene-CanVar Clinical Guideline Working Group, Expert Network Members
Oct 01, 2021
DICER1 syndrome is a rare genetic disorder that predisposes to a wide spectrum of tumors. Developing surveillance protocols for this syndrome is challenging because uncertainty exists about the clinical efficacy of surveillance...
The social network structure of a dynamic group of dairy cows
Natasha K. Boyland, David T. Mlynski, Richard James, Lauren J. N. Brent, Darren P. Croft
Jan 01, 2016
Social relationships have been shown to significantly impact individual and group success in wild animal populations, but are largely ignored in farm animal management. There are substantial gaps in our knowledge of how farm...
The Neurology and Neurosurgery Interest Group (NANSIG)-ten years of cultivating interest in clinical neurosciences.
Jay J Park, Setthasorn Zhi Yang Ooi, Conor S Gillespie, Soham Bandyopadhyay, Yasir A Chowdhury, Georgios Solomou, Melissa Gough, Ulrick Sidney Kanmounye, Alvaro Yanez Touzet, Michael TC Poon, Andreas K Demetriades, Michael D Jenkinson, Alistair Jenkins, Neurology and Neurosurgery Interest Group (NANSIG)
Feb 18, 2022
Collaboration and successful teamworking are important components of clinical practise, and these skills should be cultivated early in medical school. The breadth of current medical school curricula means that students often...
The social network structure of a dynamic group of dairy cows
Natasha K. Boyland, David T. Mlynski, Richard James, Lauren J. N. Brent, Darren P. Croft
Jan 01, 2016
Social relationships have been shown to significantly impact individual and group success in wild animal populations, but are largely ignored in farm animal management. There are substantial gaps in our knowledge of how farm...
Consensus for genes to be included on cancer panel tests offered by UK genetics services
Amy Taylor, Angela F Brady, Ian M Frayling, Helen Hanson, Marc Tischkowitz, Clare Turnbull, Lucy Side, UK Cancer Genetics Group (UK-CGG)
May 18, 2018
Genetic testing for hereditary cancer predisposition has evolved rapidly in recent years with the discovery of new genes, but there is much debate over the clinical utility of testing genes for which there are currently limited...
The Neurology and Neurosurgery Interest Group (NANSIG)-ten years of cultivating interest in clinical neurosciences.
Jay J Park, Setthasorn Zhi Yang Ooi, Conor S Gillespie, Soham Bandyopadhyay, Yasir A Chowdhury, Georgios Solomou, Melissa Gough, Ulrick Sidney Kanmounye, Alvaro Yanez Touzet, Michael TC Poon, Andreas K Demetriades, Michael D Jenkinson, Alistair Jenkins, Neurology and Neurosurgery Interest Group (NANSIG)
Mar 31, 2022
Collaboration and successful teamworking are important components of clinical practise, and these skills should be cultivated early in medical school. The breadth of current medical school curricula means that students often...
A single ultrasensitive assay for detection and discrimination of tau aggregates of Alzheimer and Pick diseases
Michael A. Metrick, Natália do Carmo Ferreira, Eri Saijo, Allison Kraus, Kathy Newell, Gianluigi Zanusso, Michele Vendruscolo, Bernardino Ghetti, Byron Caughey
Jun 06, 2020
Abstract: Multiple neurodegenerative diseases are characterized by aggregation of tau molecules. Adult humans express six isoforms of tau that contain either 3 or 4 microtubule binding repeats (3R or 4R tau). Different diseases...
Investigation and Management of Apparently Sporadic Central Nervous System Haemangioblastoma for Evidence of Von Hippel–Lindau Disease
Hugh Furness, Louay Salfity, Johanna Devereux, Dorothy Halliday, Helen Hanson, Deborah M. Ruddy, UK VHL Study Group UK VHL Study Group, Neha Shah, George Sultana, Emma R. Woodward, Richard N. Sandford, Katie M. Snape, Eamonn R. Maher
Sep 17, 2021
Haemangioblastomas are rare, highly vascularised tumours that typically occur in the cerebellum, brain stem and spinal cord. Up to a third of individuals with a haemangioblastoma will have von Hippel–Lindau (VHL) disease....
A single ultrasensitive assay for detection and discrimination of tau aggregates of Alzheimer and Pick diseases.
Michael A Metrick, Natália do Carmo Ferreira, Eri Saijo, Allison Kraus, Kathy Newell, Gianluigi Zanusso, Michele Vendruscolo, Bernardino Ghetti, Byron Caughey
Mar 26, 2020
Multiple neurodegenerative diseases are characterized by aggregation of tau molecules. Adult humans express six isoforms of tau that contain either 3 or 4 microtubule binding repeats (3R or 4R tau). Different diseases involve...
Seed Alzheimer Disease Tau neurodegeneration protein misfolding RT-QuIC Chronic Traumatic Encephalopathy Primary age-related tauopathy Pick disease
Published by: Acta neuropathologica communications
A single ultrasensitive assay for detection and discrimination of tau aggregates of Alzheimer and Pick diseases
Michael A., II Metrick, Natália do Carmo Ferreira, Eri Saijo, Allison Kraus, Kathy Newell, Gianluigi Zanusso, Michele Vendruscolo, Bernardino Ghetti, Byron Caughey
Feb 21, 2021
Abstract: Multiple neurodegenerative diseases are characterized by aggregation of tau molecules. Adult humans express six isoforms of tau that contain either 3 or 4 microtubule binding repeats (3R or 4R tau). Different diseases...
A single ultrasensitive assay for detection and discrimination of tau aggregates of Alzheimer and Pick diseases.
Michael A Metrick, Natália do Carmo Ferreira, Eri Saijo, Allison Kraus, Kathy Newell, Gianluigi Zanusso, Michele Vendruscolo, Bernardino Ghetti, Byron Caughey
Mar 09, 2020
Multiple neurodegenerative diseases are characterized by aggregation of tau molecules. Adult humans express six isoforms of tau that contain either 3 or 4 microtubule binding repeats (3R or 4R tau). Different diseases involve...
Alzheimer Disease Chronic Traumatic Encephalopathy neurodegeneration Pick disease Primary age-related tauopathy protein misfolding RT-QuIC Seed Tau Adult Aged Aged 80 and over Alzheimer Disease Biological Assay Biomarkers Brain Female Humans Male Middle Aged Pick Disease of the Brain protein aggregation Pathological tau Proteins
The GRAPPA-OMERACT Working Group
Ying Ying Leung, William Tillett, Ana-Maria Orbai, Alexis Ogdie, Lihi Eder, Laura C Coates, Richard Holland, Anna Antony, Niti Goel, Philip J Mease
Jun 30, 2020
The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA)-Outcome Measures in Rheumatology (OMERACT) Psoriatic Arthritis (PsA) working group provided updates at the 2019 GRAPPA annual meeting on its...
Group status, minorities and trust
We present the results of an experiment measuring the impact of low group status and relative group size on trust, trustworthiness and discrimination. Subjects interact with insiders and outsiders in trust games and periodically...
Correction to: Dexamethasone for adult patients with a symptomatic chronic subdural haematoma (Dex-CSDH) trial
Angelos G Kolias, Ellie Edlmann, Eric P Thelin, Diederik Bulters, Patrick Holton, Nigel Suttner, Kevin Owusu-Agyemang, Yahia Z Al-Tamimi, Daniel Gatt, Simon Thomson, Ian A Anderson, Oliver Richards, Peter Whitfield, Monica Gherle, Karen Caldwell, Carol Davis-Wilkie, Silvia Tarantino, Garry Barton, Hani J Marcus, Aswin Chari, Paul Brennan, Antonio Belli, Simon Bond, Carole Turner, Lynne Whitehead, Ian Wilkinson, Peter J Hutchinson, British Neurosurgical Trainee Research Collaborative (BNTRC) and Dex-CSDH Trial Collaborators
Jun 20, 2019
After publication of the original article [1], the authors notified that that one of the BNTRC institutional collaborator names was misspelled.
The GRAPPA-OMERACT Working Group
Ying Ying Leung, William Tillett, Ana-Maria Orbai, Alexis Ogdie, Lihi Eder, Laura C Coates, Richard Holland, Anna Antony, Niti Goel, Philip J Mease
Jun 30, 2020
The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA)-Outcome Measures in Rheumatology (OMERACT) Psoriatic Arthritis (PsA) working group provided updates at the 2019 GRAPPA annual meeting on its...
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