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Results: 1662
The blood metabolome of incident kidney cancer
Florence Guida, Vanessa Y Tan, Laura J Corbin, Karl Smith-Byrne, Karine Alcala, Claudia Langenberg, Isobel D Stewart, Adam S Butterworth, Praveen Surendran, David Achaintre, Jerzy Adamski, Pilar Amiano Exezarreta, Manuela M Bergmann, Caroline J Bull, Christina C Dahm, Audrey Gicquiau, Graham G Giles, Marc J Gunter, Toomas Haller, Arnulf Langhammer, Tricia L Larose, Börje Ljungberg, Andres Metspalu, Roger L Milne, David C Muller, Therese H Nøst, Elin Pettersen Sørgjerd, Cornelia Prehn, Elio Riboli, Sabina Rinaldi, Joseph A Rothwell, Augustin Scalbert, Julie A Schmidt, Gianluca Severi, Sabina Sieri, Roel Vermeulen, Emma E Vincent, Melanie Waldenberger, Nicholas J Timpson, Mattias Johansson
Oct 18, 2021
BACKGROUND: Excess bodyweight and related metabolic perturbations have been implicated in kidney cancer aetiology, but the specific molecular mechanisms underlying these relationships are poorly understood. In this study, we...
The International Human Epigenome Consortium
The International Human Epigenome Consortium (IHEC) coordinates the generation of a catalog of high-resolution reference epigenomes of major primary human cell types. The studies now presented (see the Cell Press IHEC web portal...
Acute kidney injury
T Barrett, A Khwaja, C Carmona, Y Martinez, H Nicholas, G Rogers, AS Wierzbicki, AJP Lewington, NICE Chronic Kidney Disease Guideline Development group
Sep 01, 2020
The National Institute for Health and Care Excellence (NICE) has recently updated the guideline for Acute kidney injury: prevention, detection and management (NG148), providing new recommendations on preventing acute kidney...
The blood metabolome of incident kidney cancer
Florence Guida, Vanessa Y. Tan, Laura J. Corbin, Karl Smith-Byrne, Karine Alcala, Claudia Langenberg, Isobel D. Stewart, Adam S. Butterworth, Praveen Surendran, David Achaintre, Jerzy Adamski, Pilar Amiano, Manuela M. Bergmann, Caroline J. Bull, Christina C. Dahm, Audrey Gicquiau, Graham G. Giles, Marc J. Gunter, Toomas Haller, Arnulf Langhammer, Tricia L. Larose, Börje Ljungberg, Andres Metspalu, Roger L. Milne, David C. Muller, Therese H. Nøst, Elin Pettersen Sørgjerd, Cornelia Prehn, Elio Riboli, Sabina Rinaldi, Joseph A. Rothwell, Augustin Scalbert, Julie A. Schmidt, Gianluca Severi, Sabina Sieri, Roel Vermeulen, Emma E. Vincent, Melanie Waldenberger, Nicholas J. Timpson, Mattias Johansson
Oct 07, 2021
Background: Excess bodyweight and related metabolic perturbations have been implicated in kidney cancer aetiology, but the specific molecular mechanisms underlying these relationships are poorly understood. In this study, we...
The blood metabolome of incident kidney cancer
Florence Guida, Vanessa Y Tan, Laura J Corbin, Karl Smith-Byrne, Karine Alcala, Claudia Langenberg, Isobel D Stewart, Adam S Butterworth, Praveen Surendran, David Achaintre, Jerzy Adamski, Pilar Amiano, Manuela M Bergmann, Caroline J Bull, Christina C Dahm, Audrey Gicquiau, Graham G Giles, Marc J Gunter, Toomas Haller, Arnulf Langhammer, Tricia L Larose, Börje Ljungberg, Andres Metspalu, Roger L Milne, David C Muller, Therese H Nøst, Elin Pettersen Sørgjerd, Cornelia Prehn, Elio Riboli, Sabina Rinaldi, Joseph A Rothwell, Augustin Scalbert, Julie A Schmidt, Gianluca Severi, Sabina Sieri, Roel Vermeulen, Emma E Vincent, Melanie Waldenberger, Nicholas J Timpson, Mattias Johansson
Oct 21, 2021
Background
Excess bodyweight and related metabolic perturbations have been implicated in kidney cancer aetiology, but the specific molecular mechanisms underlying these relationships are poorly understood. In this study...
Published by: PLoS Medicine
Gene Ontology Consortium
Gene Ontology Consortium
May 06, 2020
The Gene Ontology (GO; http://www.geneontology.org) is a community-based bioinformatics resource that supplies information about gene product function using ontologies to represent biological knowledge. Here we describe...
ImmUniverse Consortium
Stefania Vetrano, Gerben Bouma, Robert J Benschop, Thomas Birngruber, Antonio Costanzo, GRAM D'Haens, Loredana Frasca, Rainer Hillenbrand, Lars Iversen, Claus Johansen, Arthur Kaser, Hans JPM Koenen, Christa Noehammer, Laurent Peyrin-Biroulet, Jeroen Raes, Leonardo Ricotti, Philip Rosenstiel, Venkata P Satagopam, Stefan Schreiber, Severine Vermeire, Andreas Wollenberg, Stephan Weidinger, Daniel Ziemek, Silvio Danese, ImmUniverse Consortium
Jan 04, 2023
Immune mediated inflammatory diseases (IMIDs) are a heterogeneous group of debilitating, multifactorial and unrelated conditions featured by a dysregulated immune response leading to destructive chronic inflammation. The immune...
How do primary care doctors in England and Wales code and manage people with chronic kidney disease? Results from the National Chronic Kidney Disease Audit.
Lois G Kim, Faye Cleary, David C Wheeler, Ben Caplin, Dorothea Nitsch, Sally A Hull, UK National Chronic Kidney Disease Audit
Dec 07, 2017
BACKGROUND: In the UK, primary care records are electronic and require doctors to ascribe disease codes to direct care plans and facilitate safe prescribing. We investigated factors associated with coding of chronic kidney...
Representing kidney development using the gene ontology.
Yasmin Alam-Faruque, David P Hill, Emily C Dimmer, Midori A Harris, Rebecca E Foulger, Susan Tweedie, Helen Attrill, Douglas G Howe, Stephen Randall Thomas, Duncan Davidson, Adrian S Woolf, Judith A Blake, Christopher J Mungall, Claire O'Donovan, Rolf Apweiler, Rachael P Huntley
May 06, 2020
Gene Ontology (GO) provides dynamic controlled vocabularies to aid in the description of the functional biological attributes and subcellular locations of gene products from all taxonomic groups (www.geneontology.org). Here we...
Urine Klotho Is Lower in Critically Ill Patients With Versus Without Acute Kidney Injury and Associates With Major Adverse Kidney Events.
Javier A Neyra, Xilong Li, Federica Mescia, Victor Ortiz-Soriano, Beverley Adams-Huet, Johanne Pastor, Ming-Chang Hu, Robert D Toto, Orson W Moe, Klotho and Acute Kidney Injury (KLAKI) Study Group
Nov 27, 2019
OBJECTIVE: Klotho and Fibroblast Growth Factor (FGF)-23 were recently postulated as candidate biomarkers and/or therapeutic targets in acute kidney injury (AKI). We examined whether urine Klotho and serum intact FGF23 levels...
The SPECTRUM Consortium
M Horton, PR Perman-Howe, C Angus, J Bishop, I Bogdanovica, A Brennan, J Britton, LS Brose, J Brown, J Collin, M Dockrell, N Fitzgerald, S Friel, D Gillespie, AB Gilmore, SE Hill, C Knai, T Langley, S Martin, A McNeill, G Moore, MR Munafò, RL Murray, M Opazo Breton, J Pearce, M Petticrew, G Reid, D Robson, H Rutter, L Shahab, N Shortt, K Smith, K Syrett, L Bauld
Dec 31, 2021
The main causes of non-communicable diseases (NCDs), health inequalities and health inequity include consumption of unhealthy commodities such as tobacco, alcohol and/or foods high in fat, salt and/or sugar. These exposures...
The SPECTRUM Consortium
M Horton, PR Perman-Howe, C Angus, J Bishop, I Bogdanovica, A Brennan, J Britton, LS Brose, J Brown, J Collin, M Dockrell, N Fitzgerald, S Friel, D Gillespie, AB Gilmore, SE Hill, C Knai, T Langley, S Martin, A McNeill, G Moore, MR Munafò, RL Murray, M Opazo Breton, J Pearce, M Petticrew, G Reid, D Robson, H Rutter, L Shahab, N Shortt, K Smith, K Syrett, L Bauld
Dec 31, 2021
The main causes of non-communicable diseases (NCDs), health inequalities and health inequity include consumption of unhealthy commodities such as tobacco, alcohol and/or foods high in fat, salt and/or sugar. These exposures...
Kidney stone/Renal calculus – A case study
Shagufta Parveen
Jan 05, 2018
The prevalence of stones has been a matter of concern and has been rising over the past 30 years in an aging population. Many factors may contribute to this rise including life style changes, improved diagnostic abilities...
Published by: IJHS Medical Association
Impact of the COVID-19 pandemic on the kidney community
Duvuru Geetha, Andreas Kronbichler, Megan Rutter, Divya Bajpai, Steven Menez, Annemarie Weissenbacher, Shuchi Anand, Eugene Lin, Nicholas Carlson, Stephen Sozio, Kevin Fowler, Ray Bignall, Kathryn Ducharlet, Elliot K Tannor, Eranga Wijewickrama, Muhammad IA Hafidz, Vladimir Tesar, Robert Hoover, Deidra Crews, Charles Varnell, Lara Danziger-Isakov, Vivekanand Jha, Sumit Mohan, Chirag Parikh, Valerie Luyckx
Sep 24, 2022
The coronavirus disease 2019 (COVID-19) pandemic has disproportionately affected patients with kidney disease, causing significant challenges in disease management, kidney research and trainee education. For patients, increased...
Stability Analysis of EPC Consortium Cooperation Based on Evolutionary Game
Consortium contracting is a contracting model that China encourages and advocates. Due to the interest drive, members within the consortium are very prone to negative cooperation and midway withdrawal, which hinders the healthy...
Published by: IGI Global Scientific Publishing
The Typhoid Vaccine Acceleration Consortium (TyVAC): Vaccine effectiveness study designs
Typhoid fever is estimated to cause between 11.9-26.9 million infections globally each year with 129,000-216,510 deaths. Access to improved water sources have reduced disease incidence in parts of the world but the use of...
Overview of the Evolution of the UK Kidney Allocation Schemes
Abstract: Purpose of Review: Allocation of deceased donor kidneys for transplantation has evolved since the first utilitarian approach in 1989. This review looks at how the schemes have evolved over the ensuing three decades....
Robot-assisted kidney transplantation
Harry VM Spiers, Videha Sharma, Alexander Woywodt, Rajesh Sivaprakasam, Titus Augustine
May 09, 2022
Renal transplantation has become the gold-standard treatment for the majority of patients with established renal failure. Recent decades have seen significant progress in immunosuppressive therapies and advances in...
Comprehensive molecular characterization of mitochondrial genomes in human cancers.
Yuan Yuan, Young Seok Ju, Youngwook Kim, Jun Li, Yumeng Wang, Christopher J Yoon, Yang Yang, Inigo Martincorena, Chad J Creighton, John N Weinstein, Yanxun Xu, Leng Han, Hyung-Lae Kim, Hidewaki Nakagawa, Keunchil Park, Peter J Campbell, Han Liang, PCAWG Consortium
Aug 02, 2021
Mitochondria are essential cellular organelles that play critical roles in cancer. Here, as part of the International Cancer Genome Consortium/The Cancer Genome Atlas Pan-Cancer Analysis of Whole Genomes Consortium, which...
Mendelian Randomisation study of the influence of eGFR on coronary heart disease.
Pimphen Charoen, Dorothea Nitsch, Jorgen Engmann, Tina Shah, Jonathan White, Delilah Zabaneh, Barbara Jefferis, Goya Wannamethee, Peter Whincup, Amy Mulick Cassidy, Tom Gaunt, Ian Day, Stela McLachlan, Jacqueline Price, Meena Kumari, Mika Kivimaki, Eric Brunner, Claudia Langenberg, Yoav Ben-Shlomo, Aroon Hingorani, John Whittaker, Juan Pablo Casas, Frank Dudbridge, UCLEB Consortium
Sep 09, 2016
Impaired kidney function, as measured by reduced estimated glomerular filtration rate (eGFR), has been associated with increased risk of coronary heart disease (CHD) in observational studies, but it is unclear whether this...
Patient preferences, knowledge and beliefs about kidney allocation
Andrea Gibbons, Marco Cinnirella, Janet Bayfield, Diana Wu, Heather Draper, Rachel J Johnson, Charles RV Tomson, John LR Forsythe, Wendy Metcalfe, Damian Fogarty, Paul Roderick, Rommel Ravanan, Gabriel C Oniscu, Christopher JE Watson, J Andrew Bradley, Clare Bradley
Nov 21, 2017
OBJECTIVE: To explore how patients who are wait-listed for or who have received a kidney transplant understand the current UK kidney allocation system, and their views on ways to allocate kidneys in the future. DESIGN...
Proposing a Library Consortium Model for National Development in Zimbabwe
Collence Chisita
Jul 01, 2021
Globally library cooperation and collaboration is transforming the scholarship landscape as academic libraries battle to survive amidst escalating costs of subscriptions. Zimbabwe is no exception to this phenomenon as evidenced...
Published by: IGI Global Scientific Publishing
Apelin is expressed throughout the human kidney, is elevated in chronic kidney disease & associates independently with decline in kidney function.
Duuamene Nyimanu, Fiona A Chapman, Peter J Gallacher, Rhoda E Kuc, Thomas L Williams, David E Newby, Janet J Maguire, Anthony P Davenport, Neeraj Dhaun
Jul 20, 2022
AIMS: Chronic kidney disease (CKD) is common and cardiovascular disease (CVD) is its commonest complication. The apelin system is a potential therapeutic target for CVD but data relating to apelin in CKD are limited. We examined...
Public attitudes towards screening for kidney cancer
Laragh LW Harvey-Kelly, Hannah Harrison, Sabrina H Rossi, Simon J Griffin, Grant D Stewart, Juliet A Usher-Smith
Sep 17, 2020
BACKGROUND: Kidney cancer is often asymptomatic, leading to proposals for a screening programme. The views of the public towards introducing a new screening programme for kidney cancer are unknown. The aim of this study was to...
Kidney stone/Renal calculus – A case study
Shagufta Parveen
Jan 05, 2018
The prevalence of stones has been a matter of concern and has been rising over the past 30 years in an aging population. Many factors may contribute to this rise including life style changes, improved diagnostic abilities...
Published by: IJHS Medical Association
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