Search
Results: 28396
Patient centered guidelines for the laboratory diagnosis of Gaucher disease type 1.
A Dardis, H Michelakakis, P Rozenfeld, K Fumic, J Wagner, E Pavan, M Fuller, S Revel-Vilk, D Hughes, T Cox, J Aerts, International Working Group of Gaucher Disease (IWGGD)
Jan 22, 2023
Gaucher disease (GD) is an autosomal recessive lysosomal storage disorder due to the deficient activity of the acid beta-glucosidase (GCase) enzyme, resulting in the progressive lysosomal accumulation of glucosylceramide...
Using different Facebook advertisements to recruit men for an online mental health study
Isabella Choi, David N Milne, Nicholas Glozier, Dorian Peters, Samuel B Harvey, Rafael A Calvo
Feb 17, 2020
A growing number of researchers are using Facebook to recruit for a range of online health, medical, and psychosocial studies. There is limited research on the representativeness of participants recruited from Facebook, and the...
Protocol for a feasibility study and randomised pilot trial of a low intensity psychological intervention for depression in adults with autism
Ailsa Russell, Katherine Cooper, Stephen Barton, Ian Ensum, Daisy Gaunt, Jeremy Horwood, Barry Ingham, David Kessler, Chris Metcalfe, Dheeraj Rai, Jeremy Parr, Nicola Wiles
Dec 03, 2017
IntroductionHigh rates of co-occurring depression are reported in Autism Spectrum Disorder (ASD), a neurodevelopmental condition characterised by social communication impairments and repetitive behaviours. Cognitive behavioural...
Gray matter covariations and core symptoms of autism
Ting Mei, Alberto Llera, Dorothea L Floris, Natalie J Forde, Julian Tillmann, Sarah Durston, Carolin Moessnang, Tobias Banaschewski, Rosemary J Holt, Simon Baron-Cohen, Annika Rausch, Eva Loth, Flavio Dell'Acqua, Tony Charman, Declan GM Murphy, Christine Ecker, Christian F Beckmann, Jan K Buitelaar, EU-AIMS LEAP group
Dec 07, 2020
BACKGROUND: Voxel-based morphometry (VBM) studies in autism spectrum disorder (autism) have yielded diverging results. This might partly be attributed to structural alterations being associating with the combined influence of...
AiDAPT: automated insulin delivery amongst pregnant women with type 1 diabetes
Tara TM Lee, Corinne Collett, Mei-See Man, Matt Hammond, Lee Shepstone, Sara Hartnell, Eleanor Gurnell, Caroline Byrne, Eleanor M Scott, Robert S Lindsay, Damian Morris, Anna Brackenridge, Anna R Dover, Rebecca M Reynolds, Katharine F Hunt, David R McCance, Katharine Barnard-Kelly, David Rankin, Julia Lawton, Laura E Bocchino, Judy Sibayan, Craig Kollman, Malgorzata E Wilinska, Roman Hovorka, Helen R Murphy, AiDAPT Collaborative Group
Apr 06, 2022
BACKGROUND: Pregnant women with type 1 diabetes strive for tight glucose targets (3.5-7.8 mmol/L) to minimise the risks of obstetric and neonatal complications. Despite using diabetes technologies including continuous glucose...
Twice-Daily Theta Burst Stimulation of the Dorsolateral Prefrontal Cortex Reduces Methamphetamine Craving
Objectives: Transcranial magnetic stimulation (TMS) holds potential promise as a therapeutic modality for disorders of addiction. Our previous findings indicate that high-frequency repetitive transcranial magnetic stimulation...
Predictors of change in objectively measured and self-reported health behaviours among individuals with recently diagnosed type 2 diabetes
Laura Kuznetsov, Rebecca K Simmons, Stephen Sutton, Ann-Louise Kinmonth, Simon J Griffin, Wendy Hardeman, ADDITION-Plus study team
Jun 13, 2018
BACKGROUND: There is limited evidence about predictors of health behaviour change in people with type 2 diabetes. The aim of this study was to assess change in health behaviours over one year and to identify predictors of...
Changing mothers' perception of infant emotion
Rebecca Carnegie, C. Shepherd, R. M. Pearson, K. S. Button, M. R. Munafò, J. Evans, I. S. Penton-Voak
Feb 01, 2016
Cognitive bias modification (CBM) techniques, which experimentally retrain abnormal processing of affective stimuli, are becoming established for various psychiatric disorders. Such techniques have not yet been applied to...
Affective and cognitive orientations in group perception
Three studies examined the role of Need for Affect (NFA) and Need for Cognition (NFC) in intergroup perception. We hypothesized that NFA predicts a preference for stereotypically warm groups over stereotypically cold groups...
Rapid Assay for Sick Children with Acute Lung infection Study (RASCALS)
John Alexander Clark, Iain Robert Louis Kean, Martin D Curran, Fahad Khokhar, Deborah White, Esther Daubney, Andrew Conway Morris, Vilas Navapurkar, Josefin Bartholdson Scott, Mailis Maes, Rachel Bousfield, Theodore Gouliouris, Shruti Agrawal, David Inwald, Zhenguang Zhang, M Estée Török, Stephen Baker, Nazima Pathan
Jan 10, 2022
INTRODUCTION: Lower respiratory tract infection (LRTI) is the most commonly treated infection in critically ill children. Pathogens are infrequently identified on routine respiratory culture, and this is a time-consuming...
Measuring the Effects of Pressure on Consumer Impulse Buying Intention in Online Group Buying
Group buying organizations (GBO) have recently stepped up their well-established practice of employing super-low prices combined with limited product and service supply in a short transaction time span as a means of exerting...
Published by: IGI Global Scientific Publishing
Age at symptom onset and death and disease duration in genetic frontotemporal dementia
Katrina M Moore, Jennifer Nicholas, Murray Grossman, Corey T McMillan, David J Irwin, Lauren Massimo, Vivianna M Van Deerlin, Jason D Warren, Nick C Fox, Martin N Rossor, Simon Mead, Martina Bocchetta, Bradley F Boeve, David S Knopman, Neill R Graff-Radford, Leah K Forsberg, Rosa Rademakers, Zbigniew K Wszolek, John C van Swieten, Lize C Jiskoot, Lieke H Meeter, Elise GP Dopper, Janne M Papma, Julie S Snowden, Jennifer Saxon, Matthew Jones, Stuart Pickering-Brown, Isabelle Le Ber, Agnès Camuzat, Alexis Brice, Paola Caroppo, Roberta Ghidoni, Michela Pievani, Luisa Benussi, Giuliano Binetti, Bradford C Dickerson, Diane Lucente, Samantha Krivensky, Caroline Graff, Linn Öijerstedt, Marie Fallström, Håkan Thonberg, Nupur Ghoshal, John C Morris, Barbara Borroni, Alberto Benussi, Alessandro Padovani, Daniela Galimberti, Elio Scarpini, Giorgio G Fumagalli, Ian R Mackenzie, Ging-Yuek R Hsiung, Pheth Sengdy, Adam L Boxer, Howie Rosen, Joanne B Taylor, Matthis Synofzik, Carlo Wilke, Patricia Sulzer, John R Hodges, Glenda Halliday, John Kwok, Raquel Sanchez-Valle, Albert Lladó, Sergi Borrego-Ecija, Isabel Santana, Maria Rosário Almeida, Miguel Tábuas-Pereira, Fermin Moreno, Myriam Barandiaran, Begoña Indakoetxea, Johannes Levin, Adrian Danek, James B Rowe, Thomas E Cope, Markus Otto, Sarah Anderl-Straub, Alexandre de Mendonça, Carolina Maruta, Mario Masellis, Sandra E Black, Philippe Couratier, Geraldine Lautrette, Edward D Huey, Sandro Sorbi, Benedetta Nacmias, Robert Laforce, Marie-Pier L Tremblay, Rik Vandenberghe, Philip Van Damme, Emily J Rogalski, Sandra Weintraub, Alexander Gerhard, Chiadi U Onyike, Simon Ducharme, Sokratis G Papageorgiou, Adeline Su Lyn Ng, Amy Brodtmann, Elizabeth Finger, Rita Guerreiro, Jose Bras, Jonathan D Rohrer, FTD Prevention Initiative
Jan 27, 2020
BACKGROUND: Frontotemporal dementia is a heterogenous neurodegenerative disorder, with about a third of cases being genetic. Most of this genetic component is accounted for by mutations in GRN, MAPT, and C9orf72. In this study...
Coherent supercontinuum generation in photonic crystal fiber with all-normal group velocity dispersion
Lucy E Hooper, Peter James Mosley, Alistair C Muir, William J Wadsworth, Jonathan C Knight
Mar 14, 2011
We demonstrate supercontinuum generation in a photonic crystal fiber with all-normal group velocity dispersion. Pumping a short section of this fiber with compressed pulses from a compact amplified fiber laser generates a 200 nm...
E 8 and the average size of the 3‐Selmer group of the Jacobian of a pointed genus‐2 curve
Abstract: We prove that the average size of the 3‐Selmer group of a genus‐2 curve with a marked Weierstrass point is 4. We accomplish this by studying rational and integral orbits in the representation associated to a stably Z /...
Published by: Proceedings of the London Mathematical Society
Deconstructing depression and negative symptoms of schizophrenia; differential and longitudinal immune correlates, and response to minocycline treatment.
Carl R Krynicki, Paola Dazzan, Carmine M Pariante, Nicholas M Barnes, Rachel C Vincent, Alex Roberts, Annalisa Giordano, Andrew Watson, John Suckling, Thomas RE Barnes, Nusrat Husain, Peter B Jones, Eileen Joyce, Stephen M Lawrie, Shôn Lewis, Bill Deakin, Rachel Upthegrove, BeneMin Study team
Nov 20, 2020
BACKGROUND: Immune dysfunction has been implicated in negative symptoms of schizophrenia and also in depression. These disorders are frequently co-morbid, with some symptoms such as anhedonia and apathy common to both. The...
Escherichia Coli as a New Platform for the Study of Phosphoinositides
Sergio Botero
Jan 01, 0001
Phosphoinositides are membrane phospholipids involved in a wide variety of processes across the tree of life. In eukaryotic cells they function though their role as integral membrane components, anchors for proteins, membrane...
Published by: Rockefeller University
Evaluating the effectiveness and reliability of the Vibrant Soundbridge and Bonebridge auditory implants in clinical practice
Deborah Vickers, Angela Canas, Aneeka Degun, John Briggs, Mina Bingham, Joseph Toner, Huw Cooper, Sarah Rogers, Stacey Cooper, Richard Irving, Patrick Spielman, Samantha Batty, Stephen Jones, Abi Asher, Mark Chung, Neil Donnelly, Anna Skibinska, Robert Gardner, Chris Raine, Rachel Andrew, Kevin Green, Hashmat Ghulam, Terry Nunn, Dan Jiang, Severin Fürhapter, Michael Urban, Kate Hanvey, Sarah Flynn, David Lovegrove, Shakeel Saeed
Jul 02, 2020
BACKGROUND: The Vibrant Soundbridge middle ear implant and the Bonebridge bone conducting hearing device are hearing implants that use radio frequency transmission to send information from the sound processor to the internal...
A Novel Trust Model for Secure Group Communication in Distributed Computing
Distributed networks are networks in which each node can act as a server or client and hence any node can provide service to any other node. In such a scenario, establishing a trust model between the service providing user and...
Published by: IGI Global Scientific Publishing
Dexamethasone in Hospitalized Patients with Covid-19.
RECOVERY Collaborative Group, Peter Horby, Wei Shen Lim, Jonathan R Emberson, Marion Mafham, Jennifer L Bell, Louise Linsell, Natalie Staplin, Christopher Brightling, Andrew Ustianowski, Einas Elmahi, Benjamin Prudon, Christopher Green, Timothy Felton, David Chadwick, Kanchan Rege, Christopher Fegan, Lucy C Chappell, Saul N Faust, Thomas Jaki, Katie Jeffery, Alan Montgomery, Kathryn Rowan, Edmund Juszczak, J Kenneth Baillie, Richard Haynes, Martin J Landray
Sep 03, 2020
BACKGROUND: Coronavirus disease 2019 (Covid-19) is associated with diffuse lung damage. Glucocorticoids may modulate inflammation-mediated lung injury and thereby reduce progression to respiratory failure and death. METHODS: In...
Administration Oral Aged Aged 80 and over Anti-Infective Agents covid-19 Dexamethasone Drug Therapy Combination Female Glucocorticoids Hospitalization Humans Injections Intravenous Kaplan-Meier Estimate Length of Stay Male Odds Ratio Oxygen Inhalation Therapy Respiration Artificial United Kingdom COVID-19 Drug Treatment
Effect of Hydroxychloroquine in Hospitalized Patients with Covid-19.
RECOVERY Collaborative Group, Peter Horby, Marion Mafham, Louise Linsell, Jennifer L Bell, Natalie Staplin, Jonathan R Emberson, Martin Wiselka, Andrew Ustianowski, Einas Elmahi, Benjamin Prudon, Tony Whitehouse, Timothy Felton, John Williams, Jakki Faccenda, Jonathan Underwood, J Kenneth Baillie, Lucy C Chappell, Saul N Faust, Thomas Jaki, Katie Jeffery, Wei Shen Lim, Alan Montgomery, Kathryn Rowan, Joel Tarning, James A Watson, Nicholas J White, Edmund Juszczak, Richard Haynes, Martin J Landray
Dec 17, 2020
BACKGROUND: Hydroxychloroquine and chloroquine have been proposed as treatments for coronavirus disease 2019 (Covid-19) on the basis of in vitro activity and data from uncontrolled studies and small, randomized trials. METHODS...
A modified Delphi study to identify the features of high quality measurement plans for healthcare improvement projects.
Thomas Woodcock, Yewande Adeleke, Christine Goeschel, Peter Pronovost, Mary Dixon-Woods
Feb 15, 2020
BACKGROUND:The design and execution of measurement in quality improvement (QI) initiatives is often poor. Better guidance on "what good looks like" might help to mitigate some of the problems. We report a consensus-building...
Published by: BMC medical research methodology
|
23 |