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Results: 9737
Using a multi-stakeholder experience-based design process to co-develop the Creating Active Schools Framework.
Andy Daly-Smith, Thomas Quarmby, Victoria SJ Archbold, Nicola Corrigan, Dan Wilson, Geir K Resaland, John B Bartholomew, Amika Singh, Hege E Tjomsland, Lauren B Sherar, Anna Chalkley, Ash C Routen, Darren Shickle, Daniel D Bingham, Sally E Barber, Esther van Sluijs, Stuart J Fairclough, Jim McKenna
Feb 07, 2020
Imaging tau burden in dementia with Lewy bodies using [18F]-AV1451 positron emission tomography.
Elijah Mak, Nicolas Nicastro, Maura Malpetti, George Savulich, Ajenthan Surendranathan, Negin Holland, Luca Passamonti, P Simon Jones, Stephen F Carter, Li Su, Young T Hong, Tim D Fryer, Guy B Williams, Franklin Aigbirhio, James B Rowe, John T O'Brien
Nov 17, 2020
Alzheimer's disease (AD) pathology is frequently observed as a comorbidity in people with dementia with Lewy bodies (DLB). Here, we evaluated the in vivo distribution of tau burden and its influence on the clinical phenotype of...
Amyloid Dementia Lewy Bodies Neuroinflammation Tau Aged Aged 80 and over Carbolines Female Fluorine Radioisotopes Humans Inflammation Lewy Body Disease Male Microglia Middle Aged Phenotype Positron-Emission Tomography Radioisotopes Radiopharmaceuticals Severity of Illness Index Temporal Lobe tau Proteins
Risk factors and the natural history of accelerated knee osteoarthritis
Jeffrey B Driban, Matthew S Harkey, Mary F Barbe, Robert J Ward, James W Mackay, Julie E Davis, Bing Lu, Lori Lyn Price, Charles B Eaton, Grace H Lo, Timothy E McAlindon
May 29, 2021
BACKGROUND: Osteoarthritis is generally a slowly progressive disorder. However, at least 1 in 7 people with incident knee osteoarthritis develop an abrupt progression to advanced-stage radiographic disease, many within...
Frequent long-range epigenetic silencing of Protocadherin gene clusters on chromosome 5q31 in Wilms' Tumor
A R Dallosso, A L Hancock, M Szemes, Kim Moorwood, L Chilukamarri, H H Tsai, A Sarkar, J Barasch, R Vuononvirta, C Jones, K Pritchard-Jones, B Royer-Pokora, S B Lee, C Owen, S Malik, Y Feng, M Frank, Andrew Ward, K W Brown, K Malik
Nov 26, 2009
Wilms' tumour (WT) is a pediatric tumor of the kidney that arises via failure of the fetal developmental program. The absence of identifiable mutations in the majority of WTs suggests the frequent involvement of epigenetic...
Baseline and longitudinal grey matter changes in newly diagnosed Parkinson's disease
Elijah Mak, Li Su, Guy B Williams, Michael J Firbank, Rachael A Lawson, Alison J Yarnall, Gordon W Duncan, Adrian M Owen, Tien K Khoo, David J Brooks, James B Rowe, Roger A Barker, David J Burn, John T O'Brien
Nov 09, 2015
Parkinson’s disease Dementia neurodegeneration Neuroimaging Adult Aged Aged 80 and over Brain Mapping Cognition Disorders Female Gray Matter Humans Longitudinal Studies Magnetic Resonance Imaging Male Middle Aged Neuropsychological Tests Parkinson Disease Retrospective Studies Severity of Illness Index statistics Nonparametric
Fine-mapping the HOXB region detects common variants tagging a rare coding allele
Edward J Saunders, Tokhir Dadaev, Daniel A Leongamornlert, Sarah Jugurnauth-Little, Malgorzata Tymrakiewicz, Fredrik Wiklund, Ali Amin Al Olama, Sara Benlloch, David E Neal, Freddie C Hamdy, Jenny L Donovan, Graham G Giles, Gianluca Severi, Henrik Gronberg, Markus Aly, Christopher A Haiman, Fredrick Schumacher, Brian E Henderson, Sara Lindstrom, Peter Kraft, David J Hunter, Susan Gapstur, Stephen Chanock, Sonja I Berndt, Demetrius Albanes, Gerald Andriole, Johanna Schleutker, Maren Weischer, Børge G Nordestgaard, Federico Canzian, Daniele Campa, Elio Riboli, Tim J Key, Ruth C Travis, Sue A Ingles, Esther M John, Richard B Hayes, Paul Pharoah, Kay-Tee Khaw, Janet L Stanford, Elaine A Ostrander, Lisa B Signorello, Stephen N Thibodeau, Daniel Schaid, Christiane Maier, Adam S Kibel, Cezary Cybulski, Lisa Cannon-Albright, Hermann Brenner, Jong Y Park, Radka Kaneva, Jyotsna Batra, Judith A Clements, Manuel R Teixeira, Jianfeng Xu, Christos Mikropoulos, Chee Goh, Koveela Govindasami, Michelle Guy, Rosemary A Wilkinson, Emma J Sawyer, Angela Morgan, COGS-CRUK GWAS-ELLIPSE (Part of GAME-ON) Initiative, UK Genetic Prostate Cancer Study Collaborators, UK ProtecT Study Collaborators, PRACTICAL Consortium, Douglas F Easton, Ken Muir, Rosalind A Eeles, Zsofia Kote-Jarai
Sep 10, 2018
The HOXB13 gene has been implicated in prostate cancer (PrCa) susceptibility. We performed a high resolution fine-mapping analysis to comprehensively evaluate the association between common genetic variation across the HOXB...
Belimumab in kidney transplantation
Gemma D Banham, Shaun M Flint, Nicholas Torpey, Paul A Lyons, Don N Shanahan, Adele Gibson, Christopher JE Watson, Ann-Marie O'Sullivan, Joseph A Chadwick, Katie E Foster, Rachel B Jones, Luke R Devey, Anna Richards, Lars-Peter Erwig, Caroline O Savage, Kenneth GC Smith, Robert B Henderson, Menna R Clatworthy
Sep 05, 2018
The lack of star formation gradients in galaxy groups up to z tilde 1.6
F. Ziparo, P. Popesso, A. Biviano, A. Finoguenov, S. Wuyts, D. Wilman, M. Salvato, M. Tanaka, O. Ilbert, K. Nandra, D. Lutz, D. Elbaz, M. Dickinson, B. Altieri, H. Aussel, S. Berta, A. Cimatti, D. Fadda, R. Genzel, E. Le Flo'ch, B. Magnelli, R. Nordon, A. Poglitsch, F. Pozzi, M. S. Portal, L. Tacconi, F. E. Bauer, W. N. Brandt, N. Cappelluti, M. C. Cooper, J. S. Mulchaey
Oct 01, 2013
In the local Universe, galaxy properties show a strong dependence on environment. In cluster cores, early-type galaxies dominate, whereas star-forming galaxies are more and more common in the outskirts. At higher redshifts and...
The evolution of star formation activity in galaxy groups
G. Erfanianfar, P. Popesso, A. Finoguenov, S. Wuyts, D. Wilman, A. Biviano, F. Ziparo, M. Salvato, K. Nandra, D. Lutz, D. Elbaz, M. Dickinson, M. Tanaka, M. Mirkazemi, M. L. Balogh, M. B. Altieri, H. Aussel, F. Bauer, S. Berta, R. M. Bielby, N. Brandt, N. Cappelluti, A. Cimatti, M. Cooper, D. Fadda, O. Ilbert, E. Le Floch, B. Magnelli, J. S. Mulchaey, R. Nordon, J. A. Newman, A. Poglitsch, F. Pozzi
Dec 01, 2014
We study the evolution of the total star formation (SF) activity, total stellar mass (ΣM*) and halo occupation distribution (HOD) in massive haloes by using one of the largest X-ray selected sample of galaxy groups with secure...
Children's moderate-to-vigorous physical activity on weekdays versus weekend days
Keith Brazendale, Michael W Beets, Bridget Armstrong, R Glenn Weaver, Ethan T Hunt, Russell R Pate, Timothy A Brusseau, Amy M Bohnert, Timothy Olds, Rafael M Tassitano, Maria Cecilia M Tenorio, Jeanette Garcia, Lars B Andersen, Rachel Davey, Pedro C Hallal, Russell Jago, Elin Kolle, Susi Kriemler, Peter L Kristensen, Soyang Kwon, Jardena J Puder, Jo Salmon, Luis B Sardinha, Esther Mf van Sluijs, International Children’s Accelerometry Database (ICAD) Collaborators
Feb 08, 2021
PURPOSE: The Structured Days Hypothesis (SDH) posits that children's behaviors associated with obesity - such as physical activity - are more favorable on days that contain more 'structure' (i.e., a pre-planned, segmented, and...
The Broad-band Counterpart of the Short GRB 200522A at $z=0.5536$
W. Fong, T. Laskar, J. Rastinejad, A. Rouco Escorial, G. Schroeder, J. Barnes, C. D. Kilpatrick, K. Paterson, E. Berger, B. D. Metzger, Y. Dong, A. E. Nugent, R. Strausbaugh, P. K. Blanchard, A. Goyal, A. Cucchiara, G. Terreran, K. D. Alexander, T. Eftekhari, C. Fryer, B. Margalit, R. Margutti, M. Nicholl
Jan 10, 2021
We present the discovery of the radio afterglow and near-infrared (NIR) counterpart of the Swift short GRB 200522A, located at a small projected offset of $\approx 1$ kpc from the center of a young, star-forming host galaxy at...
The Broad-band Counterpart of the Short GRB 200522A at $z=0.5536$
W. Fong, T. Laskar, J. Rastinejad, A. Rouco Escorial, G. Schroeder, J. Barnes, C. D. Kilpatrick, K. Paterson, E. Berger, B. D. Metzger, Y. Dong, A. E. Nugent, R. Strausbaugh, P. K. Blanchard, A. Goyal, A. Cucchiara, G. Terreran, K. D. Alexander, T. Eftekhari, C. Fryer, B. Margalit, R. Margutti, M. Nicholl
Jan 10, 2021
We present the discovery of the radio afterglow and near-infrared (NIR) counterpart of the Swift short GRB 200522A, located at a small projected offset of $\approx 1$ kpc from the center of a young, star-forming host galaxy at...
Additive Manufacturing of Multi-Scale Porous Soft Tissue Implants That Encourage Vascularization and Tissue Ingrowth.
Fergal B Coulter, Ruth E Levey, Scott T Robinson, Eimear B Dolan, Stefano Deotti, Michael Monaghan, Peter Dockery, Brian S Coulter, Liam P Burke, Aoife J Lowery, Rachel Beatty, Ryan Paetzold, James J Prendergast, Gabriella Bellavia, Stefania Straino, Francesca Cianfarani, Monica Salamone, Carmelo M Bruno, Kevin M Moerman, Giulio Ghersi, Garry P Duffy, Eoin D O'Cearbhaill
Jun 24, 2021
Medical devices, such as silicone-based prostheses designed for soft tissue implantation, often induce a suboptimal foreign-body response which results in a hardened avascular fibrotic capsule around the device, often leading to...
3D-HST+CANDELS
A. van der Wel, M. Franx, P. G. van Dokkum, R. E. Skelton, I. G. Momcheva, K. E. Whitaker, G. B. Brammer, E. F. Bell, H.-W. Rix, S. Wuyts, H. C. Ferguson, B. P. Holden, G. Barro, A. M. Koekemoer, Y.-Y. Chang, E. J. McGrath, B. Häussler, A. Dekel, P. Behroozi, M. Fumagalli, J. Leja, B. F. Lundgren, M. V. Maseda, E. J. Nelson, D. A. Wake, S. G. Patel, I. Labbé, S. M. Faber, N. A. Grogin, D. D. Kocevski
Jun 10, 2014
Spectroscopic+photometric redshifts, stellar mass estimates, and rest-frame colors from the 3D-HST survey are combined with structural parameter measurements from CANDELS imaging to determine the galaxy size-mass distribution...
DDX3X loss is an adverse prognostic marker in diffuse large B-cell lymphoma and is associated with chemoresistance in aggressive non-Hodgkin lymphoma subtypes.
Atish Kizhakeyil, Nurmahirah Binte Mohammed Zaini, Zhi Sheng Poh, Brandon Han Siang Wong, Xinpeng Loh, Aik Seng Ng, Zun Siong Low, Praseetha Prasannan, Chun Gong, Michelle Guet Khim Tan, Chandramouli Nagarajan, Dachuan Huang, Pang Wan Lu, Jing Quan Lim, Sharon Barrans, Choon Kiat Ong, Soon Thye Lim, Wee Joo Chng, George Follows, Daniel J Hodson, Ming Qing Du, Yeow Tee Goh, Suat Hoon Tan, Nicholas Francis Grigoropoulos, Navin Kumar Verma
Oct 22, 2021
DDX3X mutation Drug Resistance Hematolymphoid malignancy Prognosis Tumour metastasis Antineoplastic Agents Biomarkers Tumor Cell Line Tumor Cyclin D1 DEAD-box RNA Helicases Disease Progression Drug Resistance Neoplasm Humans Lymphoma Large B-Cell Diffuse Lymphoma Non-Hodgkin Mitogen-Activated Protein Kinases Mutation Prognosis STAT3 Transcription Factor Exome Sequencing
Modes of activation of organometallic iridium complexes for catalytic water and C–H oxidation
Andrew J. Ingram, Arron B. Wolk, Cornelia Flender, Jialing Zhang, Christopher J. Johnson, Ulrich Hintermair, Robert H. Crabtree, Mark A. Johnson, Richard N. Zare
Jan 06, 2014
Sodium periodate (NaIO4) is added to Cp*IrIII (Cp* = C5Me5–) or (cod)IrI (cod = cyclooctadiene) complexes, which are water and C–H oxidation catalyst precursors, and the resulting aqueous reaction is investigated from...
Structure and triclustering in Ba-Al-O glass
Glass-forming ability in the (BaO) x(Al 2O 3) 1-x system (0≤x≤1) was investigated by using the containerless aerodynamic levitation and laser-heating method. The main glass-forming region was found to occur for 0.40(2) ≤x≤...
A study of L-band scintillations and total electron content at an equatorial station, Lagos, Nigeria
A O Adewale, E O Oyeyemi, A B Adeloye, Cathryn N Mitchell, Julian A R Rose, P J Cilliers
Apr 07, 2012
In this paper we present the first results from measurements of scintillation and total electron content (TEC) from an equatorial station, Lagos (Latitude 6.5 N, Longitude 3.4 E, magnetic latitude 3.03 S), Nigeria, using a...
Mechanistic insights into the detection of free fatty and bile acids by ileal glucagon-like peptide-1 secreting cells.
Deborah A Goldspink, Van B Lu, Lawrence J Billing, Pierre Larraufie, Gwen Tolhurst, Fiona M Gribble, Frank Reimann
Jan 31, 2018
OBJECTIVES: The aim of this study was to investigate the electrical properties of ileal Glucagon-like peptide 1 (GLP-1) secreting L-cells using murine organoid cultures and the electrophysiological and intracellular signaling...
Molecularly rigid microporous polyamine captures and stabilizes conducting platinum nanoparticle networks
Daping He, Dong Sheng He, Jinlong Yang, Ze Xian Low, Richard Malpass-Evans, Mariolino Carta, Neil B. Mckeown, Frank Marken
Aug 31, 2016
A molecularly rigid polyamine based on a polymer of intrinsic microporosity (PIM-EA-TB) is shown to capture and stabilize platinum nanoparticles during colloid synthesis in the rigid framework. Stabilization here refers to...
Oscillatory underpinnings of mismatch negativity and their relationship with cognitive function in patients with schizophrenia.
Muzaffer Kaser, Fruzsina Soltesz, Phil Lawrence, Sam Miller, Chris Dodds, Rodney Croft, Robert B Dudas, Rashid Zaman, Emilio Fernandez-Egea, Ulrich Müller, Anna Dean, Edward T Bullmore, Pradeep J Nathan
Aug 21, 2017
BACKGROUND: Impairments in mismatch negativity (MMN) generation have been consistently reported in patients with schizophrenia. However, underlying oscillatory activity of MMN deficits in schizophrenia and the relationship with...
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