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Addressing ethical gaps in ‘Technology for Good’
This paper identifies and addresses persistent gaps in the consideration of ethical practice in ‘technology for good’ development contexts. Its main contribution is to model an integrative approach using multiple...
Social and ecological dominance orientations
In this article, we examine the roles of social dominance orientation (SDO) and ecological dominance orientation (EDO) as predictors of climate change risk and threat perceptions and associated pro-environmental policy...
Re-purposing Universities
As the extent of damage to environmental systems from our business-as-usual activity becomes ever more alarming, Universities as core social institutions are under pressure to help society lead the transition to a...
Sparring dynamics and individual laterality in male South African giraffes
Abstract: Sparring by male giraffes has been commonly reported since its first description in 1958 and is believed to play a role in establishing male dominance hierarchies. However, despite being often documented, quantitative...
Evidence for mature bulges and an inside-out quenching phase 3 billion years after the Big Bang
S. Tacchella, C. M. Carollo, A. Renzini, N. M. Förster Schreiber, P. Lang, S. Wuyts, G. Cresci, A. Dekel, R. Genzel, S. J. Lilly, C. Mancini, S. Newman, M. Onodera, A. Shapley, L. Tacconi, J. Woo, G. Zamorani
Apr 17, 2015
Most present-day galaxies with stellar masses ≥1011 solar masses show no ongoing star formation and are dense spheroids. Ten billion years ago, similarly massive galaxies were typically forming stars at rates of hundreds solar...
Platelet function is modified by common sequence variation in megakaryocyte super enhancers
R Petersen, JJ Lambourne, BM Javierre, L Grassi, R Kreuzhuber, D Ruklisa, IM Rosa, AR Tomé, H Elding, JP van Geffen, T Jiang, S Farrow, J Cairns, AM Al-Subaie, S Ashford, A Attwood, J Batista, H Bouman, F Burden, FA Choudry, L Clarke, P Flicek, SF Garner, M Haimel, C Kempster, V Ladopoulos, A-S Lenaerts, PM Materek, H McKinney, S Meacham, D Mead, M Nagy, CJ Penkett, A Rendon, D Seyres, B Sun, S Tuna, M-E van der Weide, SW Wingett, JH Martens, O Stegle, S Richardson, L Vallier, DJ Roberts, K Freson, L Wernisch, HG Stunnenberg, J Danesh, P Fraser, N Soranzo, AS Butterworth, JW Heemskerk, E Turro, M Spivakov, WH Ouwehand, WJ Astle, K Downes, M Kostadima, M Frontini
Aug 17, 2017
Linking non-coding genetic variants associated with the risk of diseases or disease-relevant traits to target genes is a crucial step to realize GWAS potential in the introduction of precision medicine. Here we set out to...
Adaptive finite element methods for computing band gaps in photonic crystals
In this paper we propose and analyse adaptive finite element methods for computing the band structure of 2D periodic photonic crystals. The problem can be reduced to the computation of the discrete spectra of each member of a...
Self-assembled lipoplexes of short interfering RNA (siRNA) using spermine-based fatty acid amide guanidines
Four guanidine derivatives of N4,N9-diacylated spermine have been designed, synthesized, and characterized. These guanidine-containing cationic lipids bound siRNA and formed nanoparticles. Two cationic lipids with C18...
A comparison of time-motion analysis methods for field-based sports.
Purpose. To assess the validity of a digitising time-motion analysis method for field-based sports and compare this to a notational analysis method using rugby union match play. Method. Five calibrated video cameras were located...
A comparison of time-motion analysis methods for field-based sports.
Purpose. To assess the validity of a digitising time-motion analysis method for field-based sports and compare this to a notational analysis method using rugby union match play. Method. Five calibrated video cameras were located...
GAMs with integrated model selection using penalized regression splines and applications to environmental modelling
Generalized additive models (GAMs) have been popularized by the work of Hastie and Tibshirani (Generalized Additive Models (1990)) and the availability of user friendly gam software in Splus. However, whilst it is flexible and...
The geometry of generic sliding bifurcations
Using the singularity theory of scalar functions, we derive a classification of sliding bifurcations in piecewise-smooth flows. These are global bifurcations which occur when distinguished orbits become tangent to surfaces of...
The distinct surface of human blood dendritic cells as observed following an improved isolation method
Freudenthal, P.S., and Steinman, R.M. The distinct surface of human blood dendritic cells as observed following an improved isolation method. Proc. Natl. Acad. Sci. USA 87: 7698-7702, 1990
Antigen Presentation CD45R molecule colony-stimulating factor 1 receptor leukocyte integrins mixed leukocyte reaction
Published by: The National Academy of Sciences
Difficulties in Testing the Instrument Strength Independent of Direct Effect Assumption in Mendelian Randomization
Difficulties in testing the InSIDE assumption in Mendelian randomization
The ‘ownership’ of science
Dr Catherine Rhodes is a research fellow at the Institute for Science, Ethics and Innovation specialising in the international regulations relevant to control of biotechnology. Professor John Harris is director of the Institute...
An introduction to Assessing Austerity
From a crisis of the state in Greece to bankruptcy in the city of Detroit, the effects of austerity have had stunning policy implications in much of Europe and North America since the ‘great recession’ started in 2007-08. The...
Effect of possible rotor deformation on the probability of face contact for a liquid film bearing
The possibility of face contact is examined for a coaxial rotor-stator bearing in dynamic motion constrained by a highly rotating very thin liquid film. A modified Reynolds equation for pressurised flow is coupled to the...
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