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Cover Image for Elevated free interleukin-18 associated with severity and mortality in prospective cohort study of 206 hospitalised COVID-19 patients.

Elevated free interleukin-18 associated with severity and mortality in prospective cohort study of 206 hospitalised COVID-19 patients.

Syed M T Nasser, Anas A Rana, Rainer Doffinger, Andreas Kafizas, Tauseef A Khan, Shuaib Nasser

Mar 26, 2023

Cytokines viral Autoimmunity Pneumonia coronavirus Inflammasomes

Published by: Intensive care medicine experimental

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Endothelial cell regulation of systemic haemodynamics and metabolism acts through the HIF transcription factors.

Simon Lambden, Andrew S Cowburn, David Macias, Tessa A C Garrud, Bernardo J Krause, Dino A Giussani, Charlotte Summers, Randall S Johnson

Jul 28, 2021

Background

The vascular endothelium has important endocrine and paracrine roles, particularly in the regulation of vascular tone and immune function, and it has been implicated in the pathophysiology of a range of...

metabolism blood pressure vascular endothelium HIF-1α Haemodynamics HIF-2α

Published by: Intensive care medicine experimental