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Molecular Characterization and Immuno-Reactivity Patterns of a Novel Plasmodium falciparum Armadillo-Type Repeat Protein, PfATRP.
Emmanuel Amlabu, Philip Ilani, Grace Opoku, Prince B Nyarko, Evelyn Quansah, Laty G Thiam, Manfred Anim, Reuben Ayivor-Djanie, Ojo-ajogu Akuh, Henrietta Mensah-Brown, Julian C Rayner, Gordon A Awandare
May 09, 2020
Nearly half of the genes in the Plasmodium falciparum genome have not yet been functionally investigated. We used homology-based structural modeling to identify multiple copies of Armadillo repeats within one uncharacterized...
Published by: Frontiers in cellular and infection microbiology
Characterisation of Bacteriophage-Encoded Depolymerases Selective for Key <i>Klebsiella pneumoniae</i> Capsular Exopolysaccharides.
George Blundell-Hunter, Mark C Enright, David Negus, Matthew J Dorman, Gemma E Beecham, Derek J Pickard, Phitchayapak Wintachai, Supayang P Voravuthikunchai, Nicholas R Thomson, Peter W Taylor
Aug 11, 2021
Capsular polysaccharides enable clinically important clones of Klebsiella pneumoniae to cause severe systemic infections in susceptible hosts. Phage-encoded capsule depolymerases have the potential to provide an...
Klebsiella pneumoniae bacteriophage capsular polysaccharide capsule depolymerase whole-genome sequencing (WGS) alternative antibacterial therapy jumbo phage Humans Bacteriophages Klebsiella Infections Bacterial Capsules Genome Viral Thailand Host Specificity
Published by: Frontiers in cellular and infection microbiology